Methadone Dose Conversion Unscrambled

WARNING: Methadone should only be prescribed for pain by experienced clinicians!

Indubitably, the most difficult opioid conversion challenge to prescribers and pharmacists is methadone.

Methadone to Morphine (or equivalent)   ≠   Morphine (or equivalent) to Methadone

Methadone conversion calculations cannot be bidirectional because the half-life of methadone is long, approximately 15-60 hours. Methadone therefore stays in the body for several days after discontinuation.  In essence, after calculating a conversion to morphine (or equivalent), one cannot simply stop the methadone and substitute with the equivalent dose because both drugs will remain in the body.  Careful slow titration and transition to or from methadone is vital.

Furthermore, significant pharmacokinetic intrapatient variability exists as a result of polymorphism, hence the huge half-life variation (15-60, and up to 150 hours).  And, if that’s not enough to challenge you, methadone undergoes Cytochrome P450 metabolism, 3A4, 2B6, 2C8, 2C9,2C19, and 2D6 mediated N-demethylation to 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidene (EDDP).  This of course precipitates yet another issue, significant risk for drug interactions!

It Takes a Team (L to R): Psychologist, Dr. Steve Passik; Nurse, Ms. Cindy Lord; Pharmacist, Dr. Jeffrey Fudin; Physician, Dr. Howard Smith

If the clinician can get past all these barriers, we are often left with the daunting task of converting other opioids to an equivalent dose of methadone.  Online opioid conversion calculators have been shown to vary in methadone calculation by up to 242% (Presented by Dr. Kathryn C. Shaw, Eastern States Residency Conference, Hershey PA; May 2012), which could easily be fatal.  In fact, methadone accounts for 2% of all opioids prescribed in the U.S., yet 33% of all opioid-related deaths from overdose involve methadone.  When a healthcare practitioner transitions a patient to methadone, a potential disparity in calculated dose conversions is in large part due to varying methadone conversion schematics that have heretofore by some, been considered acceptable standards.  These were suggested by Ripamonti(1998)Ayonrinde(2000), and Mercadente(2001).  Fourteen years have passed since Ripamonti’s original proposed schematic, yet until now, nobody has graphed the three strategies against one another to show the irrationality in terms of peaks and troughs over several hundred milligrams.

Graphing these schematics spurred my initiative to develop a formula that would smooth out the methadone conversion curve.  Hence, the Fudin Factor, a methadone conversion equation (Copyright, 2011) was derived.

Methadone Schematics Graphed Against Fudin Factor


A feature article appears in the September 2012 issue of Practical Pain Management that details the equation.  Click on “Mathematical Model for Methadone Conversion Examined” to read about the history of methadone, view a comparison of previously accepted schematics outlined herein, and learn about the derivation of the FUDIN FACTOR, inherent limitations, and how it compares to Ripamonti, Ayonrinde, and Mercadente.


633 thoughts on “Methadone Dose Conversion Unscrambled

  1. Hi my name is Todd. I was injured in the Army and had two surgeries. I became addicted to opiates due to my surgeries. And I ended up at the methadone clinic, I’ve been there since 2013, and I’m way past ready to be off this stuff. I’m on 40 milligrams and I’m trying to work down to 1 or 2 milligrams then stay at that milligram for a little while before I come off. If I could stop now while I’m on 40 I would. I’m so tired of taking this or anything,I want to be free so bad. If you or anyone has any advice to help me I would greatly appreciate it. I’m trying to work ,take care of a family and all that while battling coming off. I know it’s not going to be without a fight when I stop working through withdrawals, I just want to at least soften the blow before I come off. So I’m able to work and everything. Thanks for your time

  2. Doc, I have question- I am currently on 120mg and have been on the clinic for 5 year. If I came down say to 90mg in a week or two would I feel withdrawal or would a dose as high as 90 continue to hold me?

      1. Id assume this person means methadone and I can tell her right now, her clinic will never allow her to reduce her dose by that much. Her clinic also is supposed to make her talk to the clinic Dr before doing any dose changes so I dont know why she isnt just talking to her clinic Dr. I can also say from experience that most likely she would feel significant withdraw but some people can stand much greater reductions than others or much longer time periods without the drug than others while some, like myself, cant even go one day on a slightly lower dose or they will have extreme emotional changes and mood swings due to other mental health issues but no physical withdraw symptoms. My 1 friend can go 4 days without her 30mg dose and feel totally fine while I cant make it 30 hrs without my 50mg dose b4 experiencing very uncomfortable physical withdraw (ive always been prone to RLS anyway so ofcourse that symptom is always severe 4 me when I do have any withdraw) plus the mental and emotional symptoms I already mentioned. Everyone is different and your personal response to this medication and dose changes can be vastly different than someone else’s. But as I said before, her clinic wont allow her to reduce that fast anyway. In NJ, clinics will not allow someone to reduce their dose more than 5mg per week (unless they stopped paying or are getting kicked off the program etc) so I cant imagine another state allowing a client to reduce their dose by FIFTY mg at any time no matter how high their dose is. But she should be thinking more in percentages anyway. I find that to be easier and more accurate unless youre at maybe 4mg cuz reducing by just 1 mg when youre at 4 means youre reducing by 25% which normally is a lot but going from 4 mg to 3 mg isnt quite as severe as reducing your dose by 25% if youre at a dose around 70mg of methadone. But dont get me wrong, going from 4 mg to 3 mg is still a large drop and even if you wait a month between reductions, people say they have a lot of trouble reducing their dose once they get down below 15mg. I appreciate you as a Dr actually caring about this stuff and the patients like us who have to deal with no one understanding, not even Doctors who are supposed to know about this, how SENSITIVE our bodies are to small changes! As an example, my mother’s dr put her on tramadol and told her it wasnt even an opiate, WHICH IT IS, I even used to take it as a back up when I was 1st addicted to low grade opiates and the Dr didnt have her wean off, he just said she could stop taking it after a month without problems and ofcourse, she went through withdrawl!! Its like half these Drs have no idea how easily these meds can torture you and make you sick and suicidal even!! One mg or a few hrs can make all the difference sometimes between feeling ok and wanting to die from pain and/or withdraw! I think any dr that deals with any opioids should have to experience “moderate” withdraw just ONCE from some low grade thing like Vicodin and then maybe they would take it more seriously and understand how terrifying and horrific even mild to moderate withdraw can be. This whole “withdraw is like a bad flu” has been used incorrectly for way too long cuz its nothing like that. It feels like that maybe if you add a 3 day long heart attack/anxiety attack and the worst RLS ever ( restless leg syndrome is a condition/symptom I wouldnt wish on my worst enemy) PLUS suicidal depression and then maybe youre a bit closer to what actual withdraw feels like.

    1. You would be just fine. Of course there is a large mental part to how you might react. But if you are strong minded you won’t hardly notice or not notice at all. I know from many years of use and have came off methadone 5 times in my life and 4 of them were cold turkey in county jail. One time l went from 285 milligrams to nothing in one day. I didn’t feel well for about 3 weeks but it wasn’t hell like most would say.

      1. You people are crazy I was on 100 mg a day and I started coming down every 3 days 10 mg and within 3 weeks I’m down to 15 mg and all I feel is tired a little bit of insomnia and some cold chills every now and then

  3. Hello I’m sorry im just wondering what I can do…. I was on high doses of pain meds and because they weren’t working for me as well as before and because I was testing positive for food based alcohol my Dr discharged me as a patient and recommended I get liquid methadone the day after I had major rotator cuff surgery .. so I did. The methadone doesn’t even scratch the surface of my pain and I’m having MAJOR side effects .. losing my hair and drinking to kill my pain. I just need to get back on my meds and off of this and I’m wondering if I can stop the methadone and start taking meds to thwart the withdrawals. I am on 130 MG a day

    1. Valerie, I can’t speak to all the reasons your doctor adjusted you medications and/or dose. If your doctor detected alcohol via a test, it certainly would have been a whole lot more than from food. In fact, when cooking with alcohol, it dissipates and there is generally no or very little alcohol left. Now that you are drinking alcohol to kill the pain, it is equally as problematic. I’m not saying you don’t require opioids for your pain, but you are at high risk if you use alcohol. The best solution for you is to try and find a clinical psychologist that is willing to work with you and you current doctor so that whatever the outcome, it is safe.

      1. I’ve been on methadone for over 3 years now, after several years of heroin use. Over the last few months I’ve managed to get down to 2 mg from the 80mg I had spent the majority of the time on. The last few drops in methadone have been harder than the rest. I have take homes which makes the process so much easier. My question is whether or not I can add water to my methadone and just take some of it, will the other part of the dose be compromised by the water if it sits too long?

        1. Your methadone taper should be overseen by a professional at the methadone clinic. Methadone is compatible with water and should remain stable for the expiration date listed on the bottle.

          1. Hi I’m 64 hrs off methadone and transitioning to Suboxone then off it but I want to say I come off 100 mg for 16 years and I’m not going back bc a 16 year old got into my methadone and overdosed so I’m leaving that devil and then leaving this one I know I can I do it

        2. Idk what your question really consists of, I mean don’t they tell you at your program drink water? Bc im on methadone the water is right in front of you so…what is the question you seem to have the answers to your questions

        3. Wow , congrats!!!
          Lowering from 80 – 2 is awesome.
          I just wanted to say I read somewhere if you keep liquid methadone mixed with water , to use a dark bottle to help keep fresh.
          Hope u are still doing good.

          1. I was on 90 for a yr I dropped it down to 85 but what I’m doing is on my take homes I take out 1.25ml of each one so technically I’m way lower than 85

        4. Hi Kari, I am curious to know how often did you drop your dosage and at what ml? Did you have any withdrawal symptoms since you’ve done the taper from 80ml to 2ml within months?

      2. I just wanted to comment that it’s a common misconception that most alcohol is cooked out of food, and EtG testing for alcohol is extremely sensitive, to the point that a dose of cough syrup is taking a risk. Not saying that’s the case here, but it IS possible.

      3. I’m on 65mg of meterdone can I switch to 12.mgrams of fentnlyl pat h safely to matfifen with out o er dodsing

    2. Definitely do not mix alcohol with opiates…I’ve learned the hard way with gabapentin. i’ve been tapering on methadone from 130mg down to the 10mg im on now, daily. and I don’t seem to be leveling out. A lot depends on the gabapentin now, the anxiety is much worse this time than in the past. Too much actually, This last 10mg of methadone, feels like a whole different hurdle. 130-100mg was easy. 10mg-0 feels …impossible. That security blanket does not want to leave. I’ve tried kratom. Be careful, more than a few days using it can cause a backlash. Use sparingly, Gabapentin helps a ton with withdrawal, but also, potential for abuse is there.

      Coffee, mindless television? you need lazy distractions and medical attn. I’ve tried going to detoxes here in NYC but if you’re connected to a Methadone clinic, it’s not happening. 5 day detoxes can’t really handle a methadone detox anyways…Last time I kicked methadone when I was 25 years old(32 now), I feel those 7 years by the way..Last time I kicked I didn’t get REM sleep for 2 weeks. That’s being modest. I had persisting symptoms for 6 months.
      Take comfort in knowing you’re not alone during this covid business and dealing with opiate w/d.

      1. Hello Kito, We are both in similar situations. I have tapered from 90 mg down to 20 in the past week! And I also have been dealing with extreme bouts of Anxiety and panic attacks. So bad actually that I can sometimes notice my entire head shaking, it’s horrible compared to shaky hands and legs. Email me if interested in comparing notes and sides at

      2. Hey my is Cindy and I’m 32 and I have been going to the clinic for 5 years and I quit cold turkey and it’s been 14 days and it’s hard to catch my breath and when I do back of my neck tightens and my head feels nubb an lips an feet I had the COVID-19 back like 4 months ago it feels just like that when I had the COVID-19 so I don’t know really what a going on with me can any one help please

      3. Kito, you can do this. It seems like a mountain to climb but that’s in your head. I got off 80mg in about 18 months. Key is sloooow taper. 2mg every 2 weeks. ..When I got to about 8mg I did 1mg every 2 weeks.. I was at 1mg and I’d take it every other day.. one day I said I’m done..boom from there on be strong daily, stay busy…it’s done

        1. The key to a successful methadone taper is to go very slow. The higher your dose, the quicker you can go, at least initially. However, once you get down to about 50mg, in my opinion, then take the taper slowly Take this advice however you like but if you’re on 80mgs, it should take you about 2 years to get off completely with minimal withdrawals, if any.

          1. Once he reached 8mg he tapered down 1 mg biweekly until he was able to get down to 1mg of methadone. Once he was at the 1mg dose he took his dose every other day until he decided not to take it at all. He doesn’t say how many weeks or months he stayed on 1 mg before he finished the taper.

        2. Hi, congrats! I am down to 20 mg but are feeling bad withdrawal symptoms. The pain in my legs and sweating are the worst because it keeps me from sleeping. This has also caused me to have high blood pressures during the night and until noon. How can I bear to go off last 20 mgs? Afraid of the pain…any advice?

      4. What do you mean u learned the hard way with gabapentin? Gab isnt an opiate. Also no ur not suppossed to drink while on methadone and it’s more dangerous the higher your dose and the more you drink but I do know people who drink while on methadone all the time. ive barely drank since getting on methadone like 3.5 yrs ago but I did just drink about 4 drinks at my sisters wedding over the course of 7 hrs and I was fine (I’m also on like 4 other meds ur not suppossed 2 drink on but, o well) and yea everyone says the last 15 mg are the hardest. This 1 lady said she had to reduce by 1 mg per month 4 the last 10 and she was ok. I was also planning on using gabapentin (my mom and my dog are prescribed it lol) plus kratom to help me once im down to 15 mg cuz I’m SUPER sensitive and when I taper down I can manage to not have any physical withdraw but still have crazy emotional withdraw to the point of becoming suicidal b4 I’ve even lowered it enough to START on any physical withdraw but what do u mean by “backlash”?? I’ve read tons of people talk about how kratom helped them get off methadone or other opiates and they talked about their kratom dosing schedule and how much they used etc. I know u can get addicted 2 kratom but I figure its way easier to taper off that than off methadone. Ive tapered myself off suboxone b4 down to .15 mg and then I just needed 1 nights worth of RLS medication (requip is one) and I was done, but since with methadone you CANT reduce at any amt u want, you can ONLY reduce it by 1mg per week or more at a time (unless you try 2 do it at home by measuring out half a mg or something from ur bottles daily, which sounds really hard, then I guess u could take ur full dose every month or twice a month, depending on how often u go to the clinic, cuz theres no way to measure a half mg out of the cup they give u and not drink that amount lol) I knew id need kratom 2 help me but now I’m worried cuz of what u said. I just kno I cant get off methadone without pharma help. Theres just no way. Even a 2 wk detox, which is the longest detox available, isnt gonna cut it! Methadone withdraw lasts months,as u know. Man I should’ve chosen suboxone instead of methadone but I was worried about money and bein able to pay 4 it since Medicaid doesnt cover suboxone treatment/sub Drs. If you figure it all out reply back

      5. Man, I felt exactly the same. I started goin to the methadone clinic when I was 20. I am now 42. Older people use to often say, “you’re awfully young to be starting the methadone.” I just looked at em say, ” The $500/day OC habit compared to $100/wk ($77/wk at the time I started) foe methadone maintenance says otherwise. Talk to me when youre moving 5 lbs of weed and ounce of soft/wk just to support my habit, and thats not counting the OC I was helping everyone else’s addiction out with. Methadone was a Gof send!!!!! I can truthfo say I have never in my life done an OC or Roxy, orally. I started snorting them, then progressed to banging them. After shoot OC for a month, I finally realized I was out of control, and had to do something. When I was younger, my dose was 140/mg day and I still felt like i needed aroung 200mg/day cuz I woke up at 3am every morning sweaty, anxious and irritable as hell cuz the clinic wouldnt open for 2 hrs. Now that Im older 120/mg a day is perfect. 20ore would be better, but it’s a bitch trying to go above 120mg/day in TN now. In 22 years Ive gotten off of it around 5 times. 4 of those was TN’s finest boys in blue that thought it was time to get off the done. Only 3 of those lasted longer than 3 days; and just like OP said I didn’t get any good REM sleep for 2 weeks and it took me a whole 6 long months to feel like a human again. This last time I kicked it on my own and after staying clean for 6 months, I started using again. After this last time, I realized it’ll be methadone maintenance and not methadone detox for the rest of my life. I dont mind it a bit though. The only con I can think of is one often has to plan future events around your methadone pickup day, and it’s worse if you daily, cuz then you gotta take a vaca that has a clinic somewhat near by, so you can guest dose.
        TLDR; I agree with OP it took 2 weeks before you start getting good restful REM sleep and 6 months to feel normal. But methadone is a God send for me. Ill use methadone for maintenance for the rest of my life, cuz Ill end up overdosing on heroin or fentanyl now that OCs are gone.

    3. I was on a very high prescribed dose of oxymoron due to an accident that involve my back getting broken in a couple areas that I amazingly made it without being partly paralyze now MY DOCTOR SEEN WHERE MY PSYCHIATRY DOCTOR PERSCRIBED ALPROAZOLAM FOR SEVERE ANIETY WITH SEVERE PANIC ATTACKS AND SOCIAL ANXIETY THAT LIMITS ME FROM EVEN DRIVING AND BE ABLE TO HOLD DOWN A JOB THEY CUT MY PAIN MEDS OFF WITHOUT TAPERING OR ASKING I DID NOTHING WRONG BUT NOW IM ON A MEDICATION THRU THE PSYCHIATRIC DOCTORS HAS ME ON AND I CANNOT JUST UP AND STOP TAKING IT BECUSE I COULD GO THRU WITHDRAWALS THAT COULD THROW ME INTO SEVERE Grandma SEZIEURES.if I stop taking the Alprazolam 2 mg 4 times a day and I’m prescribed methadone 135mg daily and it spent scratch the deep pain I differently daily but I get no one to listen I feel like a research animal in there clinics I just need some real help thru people that care and not use me as trial and error

      1. But are you getting someone like Insurance military Insurance to help pay? I have been on Methadone since September 11 9/11. My husband said he is stop paying in January. I will die . My Dr. knows and I have asked him to put me on some pain medication to ween me off.

    4. Why so high a dose man ?
      I weigh 260 lbs
      But I’m mostly muscle ive been on 70 MG for years I also take 6 MG klonopin a day been pretty unlucky in life w accidents want off this shit so bad .the thing is I’ll take death over withdrawal its not only physical and mental I have crazy 85 I was in a head on at 75 mph on two. Lane hwy no seatbelt thank God I wasn’t killed
      But my motor was In my
      Drivers seat.the list goes on and on.good luck all. All I remember from the accident was the sound then floating. If you would have seen my car you would never imagine the driver Jesus name amen

      1. 260 pounds of “mostly muscle” after “years” of Methadone use. Come on, we’re all friends here dude. Either you’re that one in a million or you are on one hell of an aggressive TRT regiment. Either way, just be honest.

      2. I understand perfectly taking death over withdrawals. The withdrawals got worse and worse and worse and worse as I got older. I know it sounds crazy but that sounds more welcoming than withdrawals

      3. Dose doesn’t depend on body weight.
        It’s your tolerance.
        My ex-gf gave birth on 340mg methadone and 2300mg kadian(time release morphine).
        She was 5’2″ and 90lbs before she got pregnant. She was stabilized in hospital over 47 days.
        The baby had no withdrawal and was extremely happy and healthy.
        The nurses all kept saying how lucky we were because the baby was so happy and cheerful.

    5. I’m on 170 and they say f
      If I cut off 50 mg In a week I probably would not feel shit but idk wd is tricky this being my first time in my life doing it I’ve never came down yet I just got stable off the fetty.. and I agree with the doctor, the alcohol has to stop and my methadone clinic will kick u if u test positive for alky all the time , opiates and cocaine they don’t usually kick u but the alky is a different thing for some reason idk it must have a different affect.. but u also may not be on high enough methodone I’m on 170 and it’s barely enough I have had total hip replacement shattered pelvis methodone is not a good analgesic for pain statistics say also so hopefully with new CDC softening guidelines more people can go back to pain management but regardless the alcohol will stop u from getting anything

    6. You can do anything you want to do. But l will tell you that l have a fused spine, l2-l3, fibromyalgia, tendonitis, and a few other ailments and have used many pain killers in my life and methadone is the best and most powerful pain killer l have ever used.

  4. Excellent work Dr Fudin. My question is regarding side effects of a single dose of methadone versus the morphine equivalent. Is there evidence, or in your educated opinion, does the respiratory depressant effect follow the same curve as the equianalgesic effect? Or would a single dose of say, 500mg morphine sulfate produce more pronounced RD than the equivalent dose of methadone in an opioid tolerant individual? Or vice-verse? Would 200mg methadone cause 10x the amount of RD as 20mg, or is there also an exponential curve there? I have stage 4 COPD with multiple comorbidities, but prior to my diagnosis I was in pain management for several years, 2+ on methadone, and had no issues with respiratory depression. I stopped all opioids to eliminate my tolerance in the hope that low dose morphine would alleviate my constant air hunger, but now no pain doctor will accept me as a patient and I’m told there is no such thing as a palliative COPD patient since we tend to die suddenly and can not obtain a “6 months to live “ prognosis. I have a family doctor and 5 specialists and none of them will refer me to palliative care, only pain management. A Hospice nurse blatantly lied, stating that by law only cancer patients can be prescribed opioids in palliative care. I find it ironic that I’m slowly dying in misery and endless suffering but they’re afraid to treat me because I might die a little sooner (or become addicted). I just want a little bit of truth please. Thank you!

    1. William, The answers to your questions are too variable and complex to answer comprehensively in a forum like this. An entire daily dose of immediate release morphine should NEVER be taken once daily instead of divided doses, and YES, most definitely the risk of respiratory depression and death are high with morphine immediate release if used that way. It’s not indicated in that fashion and very dangerous. The one exception is Kadian which is a 24 hour release capsule, and it needs to be carefully titrated in opioid experienced patients by an experienced pain clinician. No other morphine product is appropriate for once daily dosing. Single dose methadone if slowly titrated by an experienced healthcare physician is very different because of the way methadone is distributed throughout the body tissues – but even then, it must be done slowly over several weeks/years, in patients who are very opioid tolerant and have used opioids regularly with no break in therapy.

      1. I have a question, however I don’t see a link to post a new question, so I hope this works. I have been on Methadone for 9 years at 90 mg. I am also Bipolar. There is a mood stabilizer called Tegretol, it says one of the side effects is euphoria. My question is, will the Methadone block the euphoria like it does with regular pain meds. I worry b/c I used to take pain pills for the euphoria.. Thank you.

        1. Tegretol will lower the blood levels of methadone after 3 weeks. Then, if you abruptly stop Tegretol, it can dangerously elevate you methadone blood levels. If your doctor wants to use something similar to Tegretol, I’d suggest Trileptal, because it does not effect the metabolizing liver enzymes the same way.

          1. Gah be careful with trileptal and methadone! I was on a really high dose of methadone when I 1st started taking trileptal so the methadone covered up the fact that the trileptal could make me super sad and depressed but once i lowered my methadone dose, all those effects from the trileptal finally came out but I had no idea cuz they werent there b4 cuz the methadone was making me happy sort of and covering it up. then during the time I lowered the methadone I was going thru horrible things like my dog dying and covid and losing my apartment & my roommates trying 2 ruin my life so I didnt realize for almost TWO YEARS that part of the reason I was crying and sad all the time was from the stupid trileptal!! I just recently stopped taking it and 95% of my sadness & negative thinking is gone!! I feel like a new person!! Now it makes sense why it seemed like the antidepressants and all these meds ive been on since I was 14 had suddenly stopped working and that nothing my dr tried was helping! I was on lots of diff meds for like 20 yrs and I never had a problem finding something that worked til after the methadone and trileptal. My dr and I already knew the trileptal made me crazy depressed at higher doses cuz the difference was so drastic and it was always 4 days after hed try 2 increase it, but we didnt realize it was the cause of my meds not working even at much lower doses and the reason I was still crying like 3 times a day yrs after the day my dog died and other bad stuff had happened (which is around when things really got bad and I cried daily starting when my dog died oct 2020 and didnt stop until 2 wks ago)so we just didnt connect it. It was after wks of ketamine infusions for my ptsd, anxiety and depression hadnt gotten me the results id expected where I decided to just try whatever long shot idea I could think of so I cut my dose in half 1 day to see what would happen and it was like a switch went off! I immediatly told my psych dr and we tapered me off the trileptal right away. I just took my last 1 yesterday. I read on web md that it has done this to other people too and I wouldnt want ANYONE to go thru what I just did 4 over a yr when it easily couldve been avoided. It even says on the bottle it can cause depression, sadness and fear but when you’ve had serious depression your whole life and are having the worst few yrs of your life plus covering up the pain with a high dose of methadone (approved by my clinic)wen u 1st start taking a new medication and add in like 4 other new medications then it can be really hard to tell if things are just fluctuating normally, staying the same amount of horrible, or if some med is actually sneakily making things worse. Its impossible 2 keep track of all these variables and pinpoint the causes of your mental health symptoms esp when you’re really sick and not doing well. No wonder getting away from my traumatic situation and being 2 yrs out from my dogs death didnt have any positive impact on my mood! It made sense that I was crying all the time and severely sad and depressed 2 yrs ago or even a year ago but it made no sense that I got worse when my situation improved and was still crying about my dog everyday (among many other things) a year after she passed.

  5. Hi Dr. Fudin,

    Very informative site, and seeing you work to revise dosing guidelines to ease patient transition is really cool. A lot of doctors dont seem particularly concerned with variability, and instead seem to want to tell the patient what “should” be working, or whats all in our heads.

    I was onoxycodone when i was 17, and then at 18 became a heroin addict for 13 years. A year and a half ago i was able to stop using with the help of a methadone program. Ive tapered from 180 to 6mg at 2mg/ 2 weeks, I was advised by the doctor that this wasnt recommended, but i want this whole experience over with.

    My question is- several months ago i started having sharp pains in my back, hip, and down my right leg after stretchinh. Eventual xray showed mild to moderate arthritis along several levels of the spine, spondylolystheis and some other stuff, It struck me as strange that this intense pain would start all of a sudden. I know withdrawal can cause hyperalgesia, but i cant seem to find anything on google about sciatica and specific. nerve pain brought on by withdrawals. I dont feel like im in intense traditional opioid withdrawal- at least not enough to cause something like this. Ive been incredibly depressed imagining that this is just how my life is going to be now, and im only 31.

    Is this something youve experienced in your practice? If so, how long does it typically take to subside after the dose is levelled off or discontinued? Ive been prescribed 3x 300mg neurontin and 2400mg ibuprofen a day, and they help, but not enough. 6’7”, 330lb male.

    Thanks for any suggestions.

    1. Trevor, It’s very possible the pain from the back pathology was masked by the methadone. And, since methadone hangs around in the tissue for several weeks, you may be getting to the point that you’re experiencing pain that you might otherwise have had if you were never on methadone (or any other opioid). In short, it probably has nothing to do with the methadone.

      1. Hi I just had a question I’ve been on methadone for 13 yrs and I hate it . This week I tried to quit cold turkey and I’m on my 5th day and the withdraws are unbearable. I’m on 180 mil a day tomorrow I’m going to dose but should I take the whole 180 or would I feel better with less thsnks

        1. Holy crap my friend, ,you should never..,go… of..f methode…,,without replacing it with suboxon,..switch been on methode for 15 years for pain,hate the drug the whole process going in,pee to make sure your taking the med, well now 3weeks off with the help of suboxon.You can get realy sickand the withdrawel without suboxon you wont be able to do it like that, You dont deserve That. ,Let me know if you were able to do it ,lm still in trasition.replacing it ,lm in so much pain,but lm a worrier, talk soon Kimmie ottawa on.

          1. At that dose, 180mg Suboxone may cause massive precipitated withdrawals, possibly even after 5 days. Steve needs to see his MMT counselor and speak with the doctor at his clinic.

          2. Hello. i know this is an older post but I’v been on methadone for 4 years. It’s been hell. I want my life back. I’m going cold Turkey off 70mg. I’ve got gabapentin to help with withdrawal. How long do i have to go cold Turkey before I can start suboxone. Please help.

        2. And yea Suboxone, haha unless u want to puke yellow bile for hours u don’t just go taking Suboxone with full agonist opiate in your system until u know you have no detectable methodone is when u might maybe take a piece of Suboxone

      2. yes I agree I said the same thing our bodies have been sedated for so.long its feeling like pain is absent actually its becoming a normal pain that needs Tylenol at least you can feel again. Thats a fr8t thing not the pain the part of having a normal pain level without opioid medication.

      1. Kratom is garbage. The only thing that helps opiate withdrawals is opiates!!! I have been going to the Methadone clinic for over a year now and my dose still isn’t working. I’m at 80mg ang by the time I wake up the next morning I am withdrawing. So therefore I use heroin and the clinic decides to drop me down to 70mg for a punishment for using! Is it safe for the doctor to play with our mg dose. Take our Methadone down if we use!!!

        1. Stop using and creating a double habit. Go up ten mgs, and let your body even out.

          Jesus why even go there if your going to continue to use?

          I’ve done the dance and if your not serious and willing to stop using when you start there, don’t make the people utilizing the program for the correct reasons look like assholes.

          It’s idiots like you that have no will or courage to deal with the small amount of sweats and possible restlessness for a day or two to even your dose and do what you should be doing, that give methadone maintenance treatment a bad name!! The people who are there for the right reasons suffer stigma because you can’t seem to get a grip.

          1. This level of intolerance doesn’t help anyone. I’m also in the clinic for my second time and this go around i have had a very hard time completely quitting. I’m also only at 80 but thankfully dont get dropped for dirty urine they just go by 5 mg. However I find im still trying to get over the hump, isuppose its behavior that needs to change and im aware of that. But my question is, are there other ways to activate these feel good chemicals we as addicts are Constantly after? Healthier ways or means?
            Smarter can feel free not to respond.

          2. I totally agree. People want the clinics closed down because of the ones who don’t take it seriously enough. If something ever happens to my clinic I don’t know what I would do.

        2. Don’t use. I’ve been in MMT for 3 years and I’m now at 126 MG. My highest was 190 MG. I have take home privileges. Only go every 21 days. Soon I’ll be applying for the last take home phase level which is 27 days take home med per month. I’m program compliant and yes it took me about a year to find my sweet spot of no withdrawals. Then I was too drowsy so I dropped it down. I don’t feel the titration as long as I only go down 3 to 5 mgs a month.

          Whatever you do, don’t use. If you go to sleep or wake up sick, your dose isn’t high enough. If you are getting drowsy, your dose is too high. Whatever you do, don’t pick up. That’s what the methadone is for, to get clean and get out of that shitty lifestyle. Don’t tell me you like it either. If you do, just wait, the day will come where you are sick and tired of it. It’s called rock bottom.

          Thoughts and prayers are with you. Find a meeting. Find someone you trust to confide in. There are NA and AA meetings world wide on Zoom since the pandemic started. Try Google for searching for a meeting near you. You don’t have to put your name or turn the camera on. Try it though. It’s kept me sober for 28 months now.

        3. Ur asking if it’s safe for the dr to drop u ? Are u really worried about safety if ur still using something that was purchased on the street ? Do u ask the dealer that ?

        4. Dude when I 1st started that would happen to me also. It means you have a really fast metabolism, that’s all. When you FIRST went in for your induction this shouldve been all taken care of. Like you shouldve gotten up to a dose that had you feeling ok with almost no cravings and feeling the way they say you should feel, not so high youre sleeping 18 hrs a day like I was lol but regardless I got up to 80 mg eventho I was only doin like 2 bags a day at that point and I still did bags for the 1st few days until I knew I could go until the next morning without withdraw. Ofcourse I still would get a runny nose by the next morning and have trouble sleeping once it was like 7 am, id have to get up and go 2 the clinic cuz I get really bad restless leg syndrome which is NOT the same thing as restlessness, by the way, people. RLS is a MONSTER and the most unbearable thing ever!! Had it so bad once I punched myself silly and put holes in my walls trying to kick and flail around trying 2 get relief. But anyway yea I too would get withdraw symptoms by the next morning even at my higher than needed dose and I just made sure not 2 do any of the things that can eat up your dose like no caffeine, no adderall, which I’m prescribed, no alcohol, no hard labor and sweating out in the sun cuz u can sweat it out like that and id go 2 bed early so I could at least get some sleep in b4 it started 2 wear off. Then I just worked at getting my take home bottles and it only took like a yr to get where I only had to come in twice a wk cuz once you have take home bottles you can just take however much of your dose you want 4 the day time and save the rest to take at night so you won’t withdraw by morning. Now I go into the clinic twice a month only so I can just space out my dose however I like. You might be able to plead with them to split your dose in half or something cuz of your issue with having withdraw by the next morning. I assume ur clinic is also only open till noon or watever so if they like you they might let you take half a dose home to take later or try to figure out some other solution. Or if you’re drinking tons of caffeine or doing any of the other dose eating activities I mentioned then try not doing those and see if it helps. But u def need to stop using if at all possible. I also think the clinics dropping peoples doses as punishment is the stupidest thing in the world! That just makes everything worse and makes people more likely to go use which is what u got in trouble for! So stupid! But if you follow all the rules thats how you get take home bottles and then u wont even have 2 worry about the issue. You think like 9 months to get a few bottles is a long time but it goes by fast. Ive been going to my clinic for 3.5 yrs and it flew by. If youre over 30 yrs old, u can count on time flying by. U know wat else? U can buy extra methadone from someone maybe and just take a few mg in the early morning if u really have to until you earn your take home bottles. There are people with actual medically proven overly fast metabolisms and if u can get something from your dr to ahow that u metabolize medicines too fast then they kinda have to work with you. Talk to ur regular dr and see if they have any ideas and act really sad and cry if u can. Ive found it takes a lot of effort sometimes to not get blown off and 2 be taken seriously.

        5. I don’t think it’s your dose, I think if you were to try 40mg am and 40mg pm you would find great relief.
          Methadone clinics don’t offer this type of dosing though.
          It’s nice when one gets take homes, splitting the dose CAN make a big difference to some.

      2. Be careful with Kratom. Many cases of salmonella have been reported. Please be more responsible when randomly throwing out there that Kratom is a “good medicine” when you know nothing of you speak, nor are you a professional. Kratom is dangerous and is not a better alternative to other opiates. Please be more responsible when giving your opinion, when ppl are desperate they can latch onto any advice a random person on the internet can give them, regardless of their lack of any professional training. Please remember just because you think it’s good it doesn’t make it a safe alternative for anyone.

    2. Are you done with Methadone now and if so how low did you have to get too before you experienced a normal sex life with normal erections … oh and at what dose level and how bad did you feel when coming off of the methadone .. I’m on 55mg and want to come off of it so bad and want to regain my sex life back to normal again …

      1. Find a good GP and get away from the clinic setting tell him you’re interested in sublocade and microdosing suboxone to get off methadone. Thanks me later

    3. I suffer from anklelosing spondylitis and it effects me the same way you described . I too am a recovering opioid addict and take methadone and am in the process of dosing down. My suggestion for you would be to ask your doctor about Humira or Embril they work miracles for the pain your describing and help prevent it from getting worse and unfortunately with diseases like arthritis and spondylitis they tend to only progress with time but fortunately there are things that can make living with them so much better. Best of luck!

    4. Coming from someone that has been through a lot of the same issues. So I do want to get off methadone mad respect for doing it that quickly. Are you off it yet or slowly doing the last 6mg? I’m not sure how active you are that could agitate your back issues. What is working for me is a Chiropractictor using a combo of things to help get things in place. Some of it can be from going down so fast from the methadone also. Good Luck!! We need more doctors to help us through this!!!!!

  6. Hi I have severe leg and foot pain I’ve been on methadone for years after about 10 years I had trouble with my heart and ended up with a pacemaker is there any way that methadone played in any part of this ?

    1. Denise, While on methadone, it can cause an irregular heartbeat, the potential risk of which can be monitored by EKG (qTc is elevated which increases risk of irregular heartbeat). Stopping methadone should prevent this if it is caught on time. I am not aware of any long term effects of methadone causing this problem.

      1. My doctor wants to switch me from 30mg of methadone daily to short acting oxycodone to help with pain. I have been on the methadone for 5 years. He cut my dose from 30mg methadone daily to 10mg daily and added 90 mg of oxycodone a day.

        I have been reading horror stories online about mixing the two and feel like I got hit by a bus for the first half of every day. Would you be available for me to hire as a consultant for a second opinion?

          1. My name is Denise. I am 57. Been on 120mg of methadone 10-12 years. Have had 4 back surgeries, 1 anterior fusion. I have Degenerative Disc Disease. I was down to 70mg methadone. Went to Suboxone. I took my last dose of methadone 70mg. last Tues, went to Suboxone clinic on Thurs. They told me to go ahead and start Suboxone that day. So I took 4mg about 3:00am and went into severe withdrawals. I’m scared to take the Suboxone now. Shat should I do. I have little faith in the Suboxone clinics knowledge now.

          2. Your doctor should know that your methadone needs to be tapered down significantly before Suboxone can be started, otherwise exactly what happened to you is expected.

        1. I wish I had a Dr. to prescribe for me like that. Iam paying 400 a month for Methadone and Iam on 90 mlg and don’t know how I’m going to pay. I just need something to help me with the withdrawal. I have been on it since 9/11

      2. Hey Dr. I have been on 220 mg methadone for years. Due to coronavirus, i lost my job. Cant afford methadone, but I can get suboxone for free. I dropped the dose from 220-160-100-60 then nothing.
        I tried to take 4 mg suboxone at 72. hours after last dose, instant withdrawal. How much longer will i be in limbo before I can take suboxone? It’s been 120 hours. Please help

        1. Stephen,

          You should work with your medical provider- generally we wait until there is moderate withdrawal. then “treat” with buprenorphine plus other medications to prevent agitation, withdrawal, nausea and vomiting. In this way, buprenorphine is used as a “rescue” instead of causing withdrawal. Again, YOU NEED TO WORK WITH A QUALIFIED PROVIDER, so that this is done properly.

        2. HOLY SHIT< YOUR DR should be monaturing you, every few days so you have enough subox to equil amount of subox ,lm at 105mg methdone, and my dr, ordered Two 8mg suboxon and every 4 houres a day you take 2mg more every 4 hours…But that was not helping with all the extremes withdrawel symptons, So 0n the 4 day we connected again the dr and myself by phone always., cause of the coronavirus..THE max was put up 32mg of SUBOXON is what you should be on or more for high your dose ,GET a new dr .who is an experts in pain AND all MEDICATIONS thoughly,ok stephen RESERCH on goggle ok bud all the best ,Kimmie G.

    2. Was prescribed methadone 21 years ago worked well, but this was the golden. Age of pain reducing medications and it wasn’t long before I found myself being prescribed nine 80mg tabs a day along with oxydose and opanna for breakthrough. While these doses worked extremely well , and for 18 years it suppressed the aftermath of a horrible motorcycle crash involving 16 broken bones, headtrauma ,collapsed lung and spinal trauma and coma,along with crushed trachea. Fast forward to 2018 , the great opioid swindle.. Doses dropped to CDC max for Opiate naive patients at 90 mme , I was tapered slowly over the 2 years but suffer from intense pain daily. I would have benefited from a dosage of three to four hundred mme,this would have been a therapeutic dosage. The dosage i am on now has me seeking a methadone treatment program but none will accept me ..WOW

      1. Finally i found a clinic to take me, starting at 30mg with gradual increases available. I already feel more pain relief than the cdc opiate naive pt level i was tapered too. I am however feeling a bit of withdrawal ,sweating ,stomach cramps,and the skin crawl thing. My question is will this go away gradually with an increase in dosage or will it persist until my body adjust to medication?

        1. You should feel better with the increase of methadone until its enough. Once you start getting drowsy about a half hour to an hour after your dose, it’s probably too high. Hopefully you have figured that out by now though, as it was about a year ago now that you posted this comment?

        2. I have chronic pain. Sent through oxycongin fentanyl, morphine nightmare. A psychiatrist asked me to try Methadone. It was a Godsend. But I ended up in a methadone clinic for 10-12 years. It works once you get to a level that is good for you. I hate to quit it, but tired of the clinic running my life. So, now I’m trying to do the Suboxone thing, which do far has been hell.

        3. I’m not a doctor but if your asking will you feel better the higher you raise your dose. That is the goal make sure when the nurse doses you let them know how your feeling.

    3. My mom is on a high dose of methadone at 300 mg a day!! About 5 years ago she had a heart attack and now has a pacemaker, she has Long QT syndrome which I’m certain is because of the methadone, a quick Google search will show you the relations to irregular heartbeats and Methadone.

      1. Anyone on 300mg a day (an insane dose), isn’t serious about anything except getting high in my opinion.
        Any doctor or clinic that would allow a patient to go this high….. I’ll keep this comment to myself.
        This is NOT how methadone works, ie; “the higher the dose the better I’ll feel”, it’s just the addictive thinking all over again (more = better).
        Ppl that are serious about getting better find the lower doses help them feel more alive and less knocked out. It just helps them to function and live life on life’s terms.
        I would highly suspect any clinic that allows that high of a dose to be very suspect, and the dosing physician really doesn’t understand the mechanics of methadone or addiction at, and aren’t serious about their patients or educated in this field enough to do more harm than good. My ex-husband, a physician, still believes that a person can’t get addicted to pain meds if their pain is real. They could only get addicted if they were recreationally using opiates. ‍♀️ I actually remember the drug reps telling this (totally wrong info) in the 1980’s. It’s part of the reason we have a lot of the issues we have today with prescribed opiates (irresponsible prescribing).
        So yes, some doctors are still ignorant to methadone dosing, the chemical makeup etc, and how the addicted brain works at all,

  7. Its Christmas Eve. My father suffered a heart attack last night and I was in the ER all night. I didnt remember that the clinic had holiday dosing hours scheduled. I have missed my dose for today as well as the take home dose for tomorrow! I am at 75mg and I have been on methadone for 2 months now., What can I do about any withdrawal. I am so scared

    1. get to an ER and ask them for clonidine or Lofexidine to blunt withdrawal symptoms until you can get back to the clinic for ore methadone. You will need to be evaluated by a doctor to prescribe these drugs at the correct dose.

    2. You should be fine. I’ve been on 60 my for a little over a year and I’ve missed mine before. It lasts so long. But if you are going to stay on it, be sure to get the next dose soon as possible. I have went 2 days without it

    3. one answer is to go to the emergency room and let them know that you are on methadone and you missed your dose what they would do is call your program and verify your dosage and dose you at the hospital.

    4. Same thing happened to me!!! I went to the ER thinking if they wont dose me at least maybe theyll give me clonidine which is a drug they use at detoxes that kinda knocks you out and helps you sleep thru opiate withdraw which is a total blessing but b4 I even got called 2 go back, my friend who I’d left a message 4 earlier, got back to me and said he had some Percocet so I bought some and didnt count it as a relapse cuz I had no choice!!! It def did NOT get me high either, it was barely enuff 2 get me thru the wkend and I struggled 2 sleep Sunday night cuz I’m NOT 1 of those people who can like go 24 hrs or more past their dose and just feel fine. My withdraw comes on very very fast and causes me to become suicidal, among other symptoms, due to my many other mental health issues and I lived alone and had dogs to take care of and there was no freaking way I was putting myself thru withdraw cuz of the clinics stupid schedule change and me being 5 minutes late. Ever since then I keep my own back up dose or two 4 emergencies. I remember when I 1st started there I even asked my counselor like what happens if I dont make it 1 day cuz I get in a car crash or something, like a fender bender and I just cant get there on time or some other thing happens and I dont get there but its not my fault and he had no answer! I thought that was insane! The WHOLE reason I started going there in the 1st place was 2 avoid withdraw! 4 me, even “mild” w/d is terrifying and unbearable and as I said, I get suicidal and I already have chronic tachycardia which means I naturally always have a faster heart rate than other people so when i go thru w/d my heart rate will go up to like 200 bpm & it feels like its gonna explode! My normal resting heart rate is about 95- 100 bpm and 4 someone like me it should be closer to 80. During your induction when they measure ur heart rate everyday, they will tend to increase your dose if they see ur resting bpm is higher than 90-95 cuz that tends to indicate ur having withdraw since it makes ur heart rate jump higher than is considered the average safe resting rate. When I have wd it makes me feel like I’m having a heart attack & an anxiety attack at the same time even during a milder episode so it’s extra scary 4 me and that’s why I’m SO GLAD I decided to take it upon myself after that day to make sure I had back up doses. You can buy methadone from someone but I wouldn’t do it unless you trust the person or at least know them. I didnt know anyone at my clinic at 1st so I just took tiny bits out of my bottles once a wk for months til I had enough 4 a cpl back up doses. I did end up having 2 use them 4 emergencies a few times esp during covid when they forced us outside the building to wait in line for 3 hrs sometimes in 25 degree weather!!! I sent the governor a letter saying this was a human rights violation cuz my feet had gone completely numb once despite being dressed properly and I thought maybe next time id end up loaing toes or a foot if I was forced to wait outside again in those temps 4 that long. It was seriously inhumane. I only had to go in twice a wk at that point so luckily I used my back up dose the next time and then there were only a few more times it was cold and a 2 hr wait and we still had 2 be outside cuz of covid rules so lucky 4 me I was ok and didnt lose a foot but 4 the people who had 2 go in daily…that wasnt right. They never shouldve been forced 2 do that! No 1 ever got back 2 me either, not the gov or anyone else I contacted multiple times. They didnt even put heaters outside which they easily couldve done!! Or give people blankets! So many clients lost their jobs cuz of these wait times but thats another issue. Just try 2 be good, follow the rules and remind ur counselor about phasing up as much as u can so u can get those take home bottles otherwise they will drag their asses about it. They also have to think your home life is stable and think youre ready b4 phasing up, its not JUST following rules & waiting the requisite time period. I know ur comment was in 2021 at some pt but everyone should know this

  8. Been on 120 mg Norco daily for 7 yrs, Dr switched me to 100 mg Hysingla w/ 1 Norco for breakout for about 7 months, I did horrible on it, constant deep heavy pain (bilateral knees and lumbar back). Now my next prescription to pick up will be 5 mg Methadone w/ 3 Norco kickers. I am very nervous about this change. Does this change sound like it is equal?
    I was in a serious industrial accident where my apprentice drove “accidentally” tried to drive a semi truck up my back while I was sitting on a bucket with a laptop. Almost splattered me on the walls. This last semester at college was very rough on Hysingla, 1 semester to go for my B.S. degree, and now trying Methadone? Yes I am scared to death this will not work, I cant do another semester like this one.

    1. I take 270 a month, 9, 5mg methadone a day.. My VA is trying to say I’m not disabled. I’ve got a lower back injury, from my tailbone & all of my lumbar. They are trying to take my only source of income. What can I do.

      1. I am sorry to hear that man and I can’t believe you are being done that way. I know it’s been a few years so I am hoping you are a 100% now but my 1 question is are you service connected? That will help you and I’m sure you have depression issues too that will help as well. Good luck man. So get into mental health.

  9. Hello,

    I’m really glad I came across this blog. This is the most information I’ve found on Methadone in one place. Thank You for all this info!

    I have been on Methadone for the past two years. I had a ugly oxy habit that morphed into heroine. I had to stop. Thank God I found Methadone. It’s saved my life. Now I’m clean and dosing down so I can live a drug free, happy life. I went up to 110 mg once a day. I’ve been going down by 5mg every week and now I’m at 45 mg. I dose down on Fridays so if I do suffer any withdraw symptoms it’ll be thru the weekend (or so I hope anyway) so it won’t affect my job.

    I don’t know if this is normal but I swear I haven’t had a single bad feeling this entire time. They keep scaring me at the clinic because they keep telling me it’s going to hit me super hard and I better brace for the coming pain. IDK why they keep doing that, seems they would be encouraging me to keep up the good work instead of scaring me to death. Here’s the thing tho, like I said, I had a ugly habit and I know my way around withdraws! If I do experience anything from coming off the methadone then so be it. I don’t want to go thru that, but if I have to then oh well.

    My question is, Do you think I’ll continue to be okay or do you think it’s going to hit me hard like they are saying?

    At this rate I’ll be methadone free the second week in August. I don’t want to slow down. I will if it becomes really bad and I can’t handle it. I hope that won’t happen tho.

    What do you think?

    1. Jennifer, It’s hard to know for sure, but since your reduction has been so gradual, you should be fine. if you do experience withdrawal symptoms, they can be treated with clonidine or Lucymera.

      1. Do clinics tend to prescribe patients clonidine or Lucymera? Or would I need to go to a regular dr for that, if I do end up needing help?

    2. Hey i have been in your situatioin. Its going to hit you hard but only when you completely stop. Its going to be tolerable but deffinitly not fun. Grt gabapentin if you can and clonadine. You will most likely have to take a week off work

    3. Lucky you. I’ve been on 90mg/day for 14 years. Started opiates after severe back injury. A few years ago I decided to taper down. At 87mg I was in unbearable withdrawals. Went back up to 90. I can’t miss a dose or even be 4 hours late before my stomach is in knots & withdrawals start. Methadone saved my life. I hate being on the borderline of disaster though. My last full blown withdrawals 14 years ago had me in the ER with kidney, urinary tract & bladder infection from dehydration. My liver test was very bad. Next it would have hit my heart. I have cardiomyopathy & certainly would have died. I haven’t touched an opiate in 14 years but the methadone has a drug addict stigma on it.
      Good luck to you Jennifer. Sounds like your on the road to being free.

      1. I have been on methadone for 14yrs this time, I’ve been messing with methadone since 1981! I’m on 170 and stuck, I have walked off on 100 twice yes it was hell.but it can be done!! Go to jail!! But I have found it really isn’t the dose it’s the length of time on. 80 mgs for 2yrs is harder than 160 for 4 months. The best thing l found was DARVON!! THEY QUIT making it of course.there is NO EASY WAY OUT, dope friends are week people, I admit it!! Good Luck. Peter

      2. I personally think it’s impossible to go into “unbearable withdrawals” going from 90mgs to 87mgs. I could almost guarantee you that if the clinic gave you 80mg one day and didn’t tell you you would not have even noticed. Most ppl go down by 5 mg at a time and almost all don’t even notice a difference. Could this be bc if your fear of going without your regular dose that’s it’s your fear putting you into this “withdrawal”. I’m in the medical research field and run clinical trials with placebo controlled drugs. It’s amazing the amount of pt’s that have side effects with a placebo as than can with an active drug. In other words, the mind is an amazing mechanism for sabotaging what may be the best thing for us because of fear.

    4. I’ve taken Methadone for 10+ years. It has helped better for my pain. Well after my doctor went out of the country( let’s clarify that she didn’t give me warning 3 months prior at my appointment) Iwent to my scheduled appointment to find out she was gone and I would need to find another doctor or go to pain manegment. We I’ve taken 40 mg for ever! Now I’m have to take myself off of it BC doctors around here don’t want ti prescribe it. I’m down to day 7 and I’m in awful pain. I’m lethargic and just feel awful. I don’t see how your not feeling any withdrawal symptoms?
      The longest I was off of it was 14 days. I’m trying to just stop but many people don’t understand the withdraw process.

      1. Why do ppl have to make comments like this? Plant in a posters desperate thread that something will “hit them hard” is the surest way for it to become a reality for them.
        I don’t understand why ppl get off on telling someone what their experience will be based on their own experience. Let’s try encouragement instead of increasing someones fear and anxiety!

    5. Hey, I couldn’t help but comment on this list as I was once in your shoes. I was on methadone for 4 years at 80mg. I decided I wanted to taper down and did so slowly; approximately 2mg a week. It took a while but I didn’t experience any withdrawal and had a positive outlook. Even when completely tapered down, I was great.
      What I did not expect was the post acute withdrawal that came about a month later. Depression came over me fast and hard. This wasn’t just me feeling a little down but rather me checking myself into behavioral health at a hospital because it was more than I thought I could bear. Extreme insomnia accompanied by restless legs, irritability and anxiety were likely to send me over a ledge if I didn’t seek help.
      I was told that this does sometimes happen and considering I had a history of depression and had been on methadone for so long that someone really should have taken the time to prepare me for coping with it which may have been as simple on going back on antidepressants before my taper with a plan in place to tackle other common symptoms such as the insomnia and restless legs.
      I stayed off of it for 4 years but admittedly was taking sleep meds such as ambien and doxepin, vyvanse for ADD and xanax for anxiety which, in my opinion for someone like me with a history of depression and abuse, wasn’t a great idea.
      I have been back on methadone for 4 years now with no plans to taper any time soon. Obviously, my first go round wasn’t great but honestly, I feel as though had I been prepared for it, I might have coped much better.
      My advice would be to keep going, keep a positive attitude but also prepare yourself for potential post acute withdrawal symptoms. Being prepared means different things for different people but do some research about this ‘delayed’ reaction and take whatever steps you feel you may need should any of these issues arise.
      Best of luck to you!

    6. I’m ezacally where u are but I thought I could cold turkey at 110 n 6 days it got really ugly so I went back at 53 mil I stopped again it’s been 11 days still n withdraws systems the best thing is to miss 4 to 5 days they cut u back 20 percent that way just go as long as u can but no more than 7 days me myself is going to fight it to the end no relapse

      1. Hi Sherri Ashley, so I’m on 240mg of methadone been on methadone since August but I want to switch to vivitrol , I was thinking if I skip a couple days I’ll feel crappy then go dose at only 100mg would it make me feel better and then I could go down from that? Or would 100mg not make me feel better ?

        1. Omg dude that’s not how methadone works…at all! Did no one teach you about methadones half life!!?? Its not a regular fast acting opiate!! For many people, they can go a day or 2 w/o feeling much withdraw, A fair # of people can go 3 to 5 days b4 they even start to feel it, a smallish amt of clients like me will start to witdrw within 10 hrs of missing their dose (beyond just feeling “off”)but it’s considered mild to very mild 4 most of us. Once its been like 5 days THEN thats when u really start to withdraw and it gets worse from there and lasts like 6 wks then u go on 2 the post acute w/d phase. You can NOT jump from 240 to 100 after 2 days and think those 2 days wouldve been a big part of ur withdraw.. Those 2 days u still have the methadone in ur system at a high dose so the w/d would barely even start by then even if u feel it kinda strongly, thats nothing compared to how bad it will get. At 240 tho u can taper down by like 15 mg per wk probably and feel ok till u get 2 like 90 mg maybe, then u will prob wanna slow it down but seriousky everyone is SO SO different, you really cant compare urself to others. I’m doing the best I can here. People have wildly different time frames, reactions and withdraw feelings and it all can happen at wildly different times 4 different pple but I do kno that methadone withdraw lasts like at least 6 wks and when u reduce ur dose u wont feel that probably 4 at least a few days, if not longer. At my clinic they don’t even allow people to taper faster than 5 mg per wk, im almost positive. When I was at 85mg they told me I wasnt allowed to go faster than 5 mg per wk but I was like “no problem there! I’m going super slow!” The reason is cuz they kno pple like to rush and think they can do it faster but doin it that way is way less effective than goin slowly & people either relapse or get sick and wanna give up the program or something else bad happens. People need to be patient and understand that goin slow & steady is the best, safest & physically healthiest way 2 do it. You dont wanna put ur body thru unnecessary stress when ur tryin to keep ur life stable. And if u have mental health issues like I do, u better be EXTRA careful when u taper cuz I can go so slow with any kind of opiate to where I wont have ANY physical w/d but I’ll still become suicidal & an emotional wreck & cry uncontrollably 4 days as long as I’m tapering. It happened when I tapered down from 6 bags of heroin per day (NOT HEROINE, heroines are female heroes-learn 2 spell ur drug of choice) to 1.5 bags over the course of 2 wks in preparation 2 get clean. I was able 2 do that w/o any physical withdraw but it messed so bad with my depression. I went from 85mg to 51mg and at 85 I could go down 3mg per wk & be fine but if I did that now, id feel it 2 much. I prefer doing 1 mg per wk now. Unfortunately ive had 2 stop my taper 4 the last 2 yrs cuz of serious mental health probs and ptsd from crap that happened 2 me during covid but I plan 2 start again asap. My friend was on 30mg 4 a while & could go 5 days w/o it and feel fine. I WISH I had that ability. At 85 mg id wake up at like 7 am with a runny nose and slight restless leg (which I get all over my body, mostly in my arms) but now that I get mostly bottles I save some to take at like 1 am so i can sleep till 11 am without any RLS or runny nose. It also seems that at a lower dose, these issues lessened even when I have 2 go in and they make me take my dose all at once, in the morning. Like, now that im at 51 I noticed even if I do that, im still ok the next morning and I don’t get the runny nose but im not sure at what dose I finally was at b4 those symptoms went away. Prob when I had tapered down to around 65 mg after about a yr at the clinic. Anyway people need to go slower! Methadone gives acute withdraw 4 over 6 wks! Thats why u cant just go 2 a detox 2 get off methadone! Cuz youde have 2 be in detox 4 like 4 wks bare minimum and the longest detox I ever heard of is only 2 wks. I dont get why people r so quick 2 wanna suffer when u could just be on a healthy dose 4 like 9 mnths then start going down like 2 mg per wk then take a break and see how u feel at a diff dose 4 a while-do that til youve been at a theraputic dose 4 the reccomended 18 to 36 months, which is any dose over 55mg & is enough 2 mostly stop ur cravings. so if u want u can actually be tapering down that whole time really slow as long as ur at a dose that is still working 4 u. So by the time the 18 mnths is done (btw its 18-36 mnths cuz that’s the time it takes 4 your brain scans 2 now look like the brain scans of a non addict aka a healthy brain- thats what the Dr at the clinic told me), youlle already be ahead of schedule and you wont have 2 hurry up and try 2 decrease so fast. I started reducing my dose like 6 mnths in cuz I knew I could easily go down 2 like 60mg and still have that b a very workable dose so I just went like 2 mg a wk over a long time so id be ahead when I finally wanted 2 really start comin down. I dunno, this was just my own strategy cuz my goal is 2 not ever feel any w/d. I cant cuz if I do then that means im already feeling suicidal and probably am at the point where I need 2 be hospitalized 4 mental health reasons. When I get down 2 like 15 mg I’m going 2 need lots of other meds 2 help me get thru the last of the reduction. Hope things went ok 4 u but I’ll prob never know.

        2. Please ask yourself why you are asking a non medical professional about your med changes or on what you should mg. You should be taking??
          Ask the physician that will be prescribing the meds to you, not a random person off the internet.
          Omg, no wonder we have such a mess of drug addicted ppl when they take medical advice from other drug addicted ppl.
          Please be smart and only listen to your doctor. Why would you take advice from someone that’s already got a problem with drug addiction, that’s why they are on this forum!

  10. Can you tell me if methadone has any affect at the same receptors or site, as pre gablin or gabas pentin

    1. Methadone works on opiate receptors, blocks NMDA receptors, and blocks reuptake of norepinephrine and serotonin. Gabapentin is very different – it blocks voltage-gated calcium channels at the alpha-2-delta subunit recprtors. This may seem like another language, but you can see here that they are VERY different!

      1. why is it that when I take gabapentin 300 mg, it stops me from having withdrawal symptoms when I don’t take my methadone?

  11. I have been on 37.5 mcg of fentanyl patches for over two years. Plus 10/350 hydrocodone 3 x daily as needed for breakthrough pain. My doctor wants to stop the fentanyl and put me on 5mg of methadone 3-4 times a day. Is this a correct conversion? I thought it was not and am concerned about withdrawal issues. Can you give me a general conversion rate from fentanyl to methadon e that I can understand. I am a male 200 lbs. 6’2″. Chronic kidney disease.

    1. Conversions need to me done gradually by a experienced clinician, especially with methadone. There is no exact equivalent because each patient is different. Gnerally speaking though, the higher your opioid dose, the less methadone will be needed to replace it. I know that sounds counter-intuitive, but methadone has very unique pharmacokinetics which is why this is so tricky. My suggestions is to work closely with your doctor.

      1. I love the way methadone makes me feel 1 and a half hours after ingested! Am I high or heavily addicted?

          1. Then your dose is too high. You should be able to function. The point of methadone isn’t to feel anything. Just to be “normallly” functioning.

        1. It’s the warm feeling you have grown accustomed to, but definitely not a high. I could never benefit from suboxone because of this. It does not give you that normal or warm feeling, but an empty shell of one.

  12. asking for a friend. Considering methadone. After researching, methadone seems like a good treatment Long term/chronic abuse of rx painkillers. Tried several different types of treatment before, last treatment was 7 months inpatient. Relapse after 3 months home. Patient tried Suboxone , which has worked before, for a little while. Patient went off suboxone, relapsed. No insurance or cash. Methadone is most cost effecient treatment available. Patient also has chronic pain and needs medication that will help quell pain. methadone seems like a great idea. what are the downsides of methadone? what advice can you give to someone about to begin methadone tx? thank you.

    1. As you can see from the article, methadone is very complex. It has many advantages for pain over traditional opioids, but many more dangers and toxicities. The selection of methadone over other options is very patients specific, so I cannot safety provide you with advise one way or the other.

      1. Hi Ive been on Methadone for the last 6 yrs, started at what is considered a low dose gradual increase til my pain was managed ( I had been on oxycotin 80mg 2x a day and then oxycodone for breakthrough pain 10mg 4x a day) However I have decreased my methadone dose down to 30mg I take 1.5 pills in morning and 1.5 in evening. I was always reluctant to go on it because of the stigma, however it has helped tremendously and now my pharmacist called my Dr and wanted to know why I was taking this( mind you my Dr called and asked if it was okay to give them this info?) I was like why does she need it, your the prescribing Dr? My Dr said that when they do the pre-auth they need the diagnosis codes ( Now there is a little reason I disnt want the pharmacistnto have this info because I happen to work at this grocery store , however now when I was talking to the pharmacy tech the other day about getting my money back( it didn’t go thru my insurance and it was do that day and then it was the weekend and I dont work weekends so I knew.I.would withdrawal so I paid for it) However I was informed at that time that they dont do pre-auths. Only for partnership health ( Medi-cal) which not! My question is 1. Can the pharmacist medicine if my Dr doesnt.drop my dosage( which what she basically said) and 2. With all the guidelines my Dr said this is a.good dose for you, your able to work and continue on with a somewhat normal life! What do I do whan is the only one who Also what is 30mg a day equivalent to morphine? Thank you in advance. Out of pain for now? Melissa

      2. My friend was taking heroine wanted to use methadone to come off the heriome he did,took 3 days worth of methadone and has stopped taking that since yesterday only used it 3 days,will his withdrawals be very bad?

        1. The Government has given pharmacists the power to over ride and turn in my Dr. If they feel my Dr. Is giving me to much pain medication. . CVS ,Walgreens and Walmart are pharmacies i stay clear of. I know several patients at my doctors have lost their scripts to these pharmacies. I go to a local pharmacy and i pay cash. Methadone is very cheap. I’ve been on methadone for about 35 plus years. I was thrown off a cliff at 14 and it did severe damage to my pelvic bone and lower back. I was on 90 mgs of methadone a day, due to new laws (War on pain patients)!!! I can only have 25mg a day. Ive gained 40 pounds and have to lay down all day from the pain. My body can’t adjust after 35 plus years on stronger dose. I tried subutex and it really helped better with pain, but not with being so tired. I went to sleeping all day and night. Im now back on 25mgs methadone a day and in constant pain, tired and out of breath. Its like being on a year long withdraw. I have nerve pain and my lower back is shot and my doctor said there is no treatment. Every day its like a toothache in my ass, kind of pain. Its really hard to live with. Im constantly angry and in a bad mood. Im constantly fearful I’ll lose what little medication i get now. I don’t understand the attack on pain patients. I had a friend who just died of cancer who was a vet and retired policeman. It was sad to see him buying pain medication on the street. His whole body was ate up with cancer and he got 3 vicodin a day. One month he over took his meds which is understandable in this case. They cut him off his meds totally and made him go to counseling to get his 3 vicodin back! I felt horrible for my dear friend. He was 89 years old and dying, why the fear of him becoming addicted! When he went into hospice 5 days before he died he finally got unlimited morphine fortunately, but he took as little as possible because he didn’t want to sleep through his last days. Obviously this was not an addict, yet was treated as one for 5 years before he died. Saddest thing I’ve had to watch! I just don’t understand the government’s plan. Take away everyone’s medication and allow China to flood cities with deadly Fentanyl. It seems like a conspiracy to get rid of addicts and pain patients. Does anyone else think this, am i just a crazy conspiracy theorist?

          1. You are definitely not crazy! It seems like politicians are now in charge of our medical care and make decisions for the doctors. I shouldn’t say this but let’s see how these same people feel if they ever have to live with chronic pain (because karma is real lol)

          2. Go to a methadone clinic & tell them you are an addict. I bought street heroin just to get myself into one… I’ve been in chronic pain since 12 (I’m 30 now) & my tattoos, dyed hair & piercings meant that things like my severe scoliosis, broken neck, fibro, endo, etc. etc. are all overlooked because I “look” drug-seeking. After over a DECADE of fighting for actual pain treatment, I gave into the stereotype/stigma, BECAME an addict (briefly), & then took myself off to treatment. My clinic prescribes up to 125mg of methadone before you get a blood evaluation to see if you’re metabolizing too fast, & if you are (I do), they’ll raise your dose even higher. Stop fighting the opiod stigma & roll with it… they’re going to call us chronic pain patients junkies anyways, so act like one, & go get yourself real pain management instead of being given 3 Vicodin & a stern talking to.

        2. I read your comment & I can kinda relate just vice verse….. I’ve been taking methadone at the clinic every day at the same time for 2 years -(if not loooonger) I’ve been taking 80 mgs every day for two years. My withdrawals from not having it didn’t truly begin to start until 36-48 hours ago.
          I’ve been researching different ways and over the counter sleep a

      3. So I used 10-20 MG of methadone a day in pill form, will 10mg of liquid methadone work the same as 10mg pills?

    2. Hi. I’m not a doctor but have been taking methadone for 10 years. It seem’s your friend may not be ready to quit his habit. It does work but you have to change everything around you , including friends who still use any anything else that can cause triggers. Addiction can be hard but a person can only quit if they want to. Also it seems expensive but $10 a day is nothing compared to a habit. Good luck I hope this helps

      1. Hello, I have a horrible spinal disease called Arachnoiditis. Ive had 2 lumbar back surgeries and 1 cervical neck surgery. I have titanium rods and screws in my lower back which has caused horrible scoliosis, DDD, Spinal stenosis and the Arachnoiditis. This is a very rare yet wicked disease. My doctor my pain is comparable to someone with stage 5 camcer that is pretty much about to lose their life. It has a very high suicide rate and I am only 38 years old. Ive been going to a methadone clinic for 3 years now and I am on 170 mgs daily. Its only controlling my pain for about 4 to 5 hours a day. Ive finally found a pain management doctor who wants to put an interthecal pump in me but he wont touch me until I get down to 90 mgs of methadone. He told me he wanted me to titrate down 20gs a day until I get to 90. Of course the clinic doctor wouldnt agree to that. He is taking me down 10 mgs every 3 days until I get to 115 mgs then he is going to do 5 mgs a day. Im scared to death bc I know what methadone withdrawals can be like. Ive kicked it completely on my own before bit I was only on 80 mgs at that time. I tried going back to my last pain management doctor to be put on 5 mg Roxycodone. That was a joke so I had to go back to the methadone. Has anyone else had this horrible disease or heard of it and can anyone give me any advice please? I am to the point I am scared that i am getting suicidal bc the pain is so unbearable and I have 2 beautiful daughters and the most wonderful husband ever. They r the glue hding me together and my good lord above of course but im really scared. I need any positive advice I can get. Thank you very much!!!

        1. Tamra, Have your pain doctor work with your methadone clinic doctor on a slow taper, so that each is in agreement and that you are comfortable with the process with minimal anxiety.

    3. Man I hope you truly don’t go down the methadone road. I am typing this after 13yrs of methadone prescription from a stupid ass dr. Who said shit here take this instead of those 10mg oxycodone. Your great President Bush even takes these. Me naive and dumb went home and told my wife about this new drug the great doctor was gonna have me on. We were happy that I would only be taking one pill. Yeah let me tell you what the truth is brother. Dr’s are being overseen now by the government and won’t be able to be able to hand out candy anymore without huge issues for them. So you will get a letter like I did that my doctor will no longer be able to write any narcotic drugs. Yeah man a fucking letter in the mail. I was days from being out when I received this letter also. The state I live in has a hard on for pain management Dr’s so I have no other local within a 2 hr ride to get meds. So I took my damn life back and closed my self in the house shut my phone off and waited. I took what came each day knowing that I was owning my life and the directions I wanted to go. No more Doctors each month and nerves of will they write the script in time for me to be off from work to go fill it blah blah blah. You know that ball and chain they have attached to you. Well I took mine off 7 days ago. I will tell everyone it can be done. Cold Turkey. It’s not a walk in the park but I have dealt with far worse pain for long periods. You get ready in your head that this is IT! You can do it. Promise!

      1. Right on. My husband used a methadone clinic to get off opioids back in 2001 and said it was the worst thing he ever came off of. Said it was pure torture. He had come down off everything at one point or another when he finally decided to try the methadone clinic and he never touched an opioids after. He had opioids prescribed a few times over the years for surgery and the like even after letting the Dr know hey he has a drug problem. Dr. Just said oh it’s fine we’ll monitor you. That’s not how that works at all. Another 4 yrs of his life playing with the devil. I approached him and suggested (he heard “Threatened”) him with methadone and he was like no thanks, I’m done. And he was. He is a binge type user I guess. He has been clean 5 yrs now. That threat of methadone looming made him snap out of it again like no thanks. Also you can be on a “maintainance” dose of methadone forever. So long as your pee tests are right they don’t kick you off it at the methadone clinic. There were people at the clinic who had been on it for years and never had a plan to go off it.

        During the recent crack down on opioids my reg Dr. Switched like all the patients to methadone because they weren’t getting any push back on it like they were other opioids. Over treating some and under treating others. That’s sad for those who need it. Pain is a very complex issue. In my eyes in our home I would rather be in pain every single day then watch addiction killing my husband. And watching my husband struggle made me scared to even try them. No thanks.

        Glad you bit the bullet and came out the other side. Congrats on that. No matter how you did it, you did it!

  13. I am currently taking 145mg of liquid methadone started at 30 mg. I just want to be off of the methadone but the doctor says itll take over a year to wean down the right way. But I want to go to a detox and just go through it. How bad would the withdrawls be and is it a wise thing to do if the detox place helps me get through it? I’ve been taking methadone for about 5 months.

    1. Either approach can be done. There are rapid detox centers that can do it as an inpatient. Not all patients respond the same. There are also drugs that can be used to blunt the withdrawal such as clonidine or Lucymera.

      1. Hello my name is Rachel. I just have a few short questions for you and would love to hear some insight on my current situation. So I was originally taking 120 milligrams of methadone for a little over a full year as medically advised before tapering down and have been properly dosing down every 7 to 10 days by 10 milligrams as required my the clinic that I attend each day and I am currently down to 40 milligrams as of this past Monday. I intend to go down another 10 milligrams next week so I will be down to 30 milligrams and from then I will go down by 2.5 milligrams every 7 to 10 days until I reach 10 milligrams. Surprisingly I have not felt any severe withdrawal symptoms as I had expected but as they say when you taper down properly you will not feel many symptoms. My question to you is that once I reach 10 milligrams per day at being at such a low dose if I took myself off if I felt okay after testing it out for a day even though I know that is against medical advice do you think I would have any serious withdrawal symptoms in doing so and have you known people to react badly in doing this? I have consulted my counselor at my clinic already about this and she has said that of course everyone’s metabolisms are different and even though I may not be feeling any withdrawal symptoms just yet it may hit me all at one time once I get down to that dose. In you professional experience have you known this to happen or are most people okay coming off at that milligram with not many symptoms? I know I am medically advised to go all the way down to 2.5 and come off completely from that dose but I’m just curious if it is possible to come off at 10 and feel okay since it is such a low dose from where I started at 120. Thanks and please respond at your earliest convenience.

        1. Rachel, Your counselor is correct – methadone has very complex metabolism and the is huge variability from person to person with each metabolic enzyme involved. There doesn’t seem to be an emergency here and your clinic is on top of things. Why risk the potential to make yourself miserable if there’s no reason to rush?

    2. Definitely DO NOT do a rapid detox!!! I did that back in early 2017, a 14-day detox & I was only on 40MG. I was in pure H*ll for an entire month. The first two weeks were absolutely unbearable. RLS all night long, making it impossible to sleep. Throwing up, diarrhea, the works. Anxiety through the roof. Sweating while being cold as heck. Cold to hot, hot to cold, cold to hot… & so on…. I was not myself for 4-5 weeks. It was something I hope I NEVER have to go through again. So definitely taper slowly. I now a whole entire year absolutely SUCKS to hear, but you’re going to thank yourself for tapering slowly! You will be okay, if you don’t want to do a full year, tell them that. A lot of Methadone doctors will try to scare you JUST to keep you on it. It’s crappy, but that’s what they do. Be strong! I hope Everything works out well for you, I wish you luck!!!
      P.S. Sorry if this is a super late reply!

      — Kara, someone who cares & wants to help all people.

    3. From personal experience, take the time to wean off slowly. I did it the hard way and was sick for at least three months after I left detox. I’m doing it the slow way now and I have t felt any withdrawals so far.

    4. Methodone for 5 months will rewire your’e brain where you could have extreme highs and lows. I’ve been on it for 10 years for pain at 240 for over 9 of them. I’m at 10 milligrams and I’m starting to feel it more then I want to. I went down 10 a week till I got to 60 then 5 a week to 20. Then I went to 1 every other day. I’m gonna hold to get used to it. Everyone is different though. I had no triggers to relapse because it was pain management but that’s not a common thing. If you feel bad from lowering just hold to adjust but know that your brain is going to take time to adjust. I have been doing nothing but reading about methodone detox for last 2 weeks to try and make my detox easier and time and patience are the key. Hope this helps.

  14. hello i just have one question. im on 15mg methadone now 3 weeks now, been slowly tapering from 30-40 mg. i have always felt withdrawl first thing in the morning. nothing severe just enough to notice. i am planning to switch to subozone , how long should i wait before taking first dose. i feel like 2 or 3 days is a little much for how low a dose i am on. after 24-30 hrs i am deffinetly im quite moderate w/d. just wonering your opinion. thanks again,

  15. My name is Kayla. I have been on liquid methadone for pain management about 2 years. I started at 30mg and upped my dosage until I was stable enough to not feel withdrawals anymore. I am now at 115mg and I’ve been at this dose for 6 months. Here’s my issue. At 5am, after I medicate and the medicine kicks in, I start to feel tired and nod out; which tells me I may be at too high of a dose- all though at about 12pm, I literally feel like I haven’t even dosed, and I experience withdrawal like symptoms!! Fever, chills, yawning… I really do not know why I am tired in the morning and feel sick only 7 hrs after dosing…. my nurse says I should up my dosage so I’m not feeling this way… but if I’m nodding out after medicating… itll only get worse as I increase my dose… PLEASE give me some advice as to what this may indicate… thanks

      1. They won’t split the dosage up if you are at s have to take the full dose early in the morning. I have been fighting cancer, but the cancer centers won’t give opioids for pain anymore. I had zero quality of life being in so much pain and agony. They had cut me off high dosage of Fentanyl patches and Dilaudis cold turkey. I said piss on it and went to the Methadone clinic. I do have a much better quality of life now, but would do much better if my 140 mg we’re to be 70 mg twice a day. None of the clinics will do this. I do it on Sunday with my take home dose and feel so much better. I’ve never had a dirty UA or had any violations yet take home doses are only given on Sundays and holidays. I think Michigan law prohibits this because of the risk of diversion. There’s so much stigma tied to it all. The police sit right outside the clinic and arrest people for even lighting a cigarette in the parking lot. It’s sad when cancer patients and people who are as unwell as I am cannot have medications that give some semblance of life quality.

        1. I am right across the state line in Indiana and get 2-week takehomes. So nice to, manage my own life now. I earned it, many years of driving an hour each way daily.
          Good luck. Also, Yes they should be able to split-dose you. In Indiana, I believe its at 5 am, and 10 when they close. It works for a lot of people though.

    1. It also takes time to get used to. I used to fall asleep and be very drowsy a few hours after i took my medication. It’s a rough side effect. However feeling sick is something that’s happening way too soon..imo..but there are several things that interact with methadone and eat up the dose….caffeine, alcohol, other medications…just a thought. Good luck! Oh and they can do a test to see how quickly your body is metabolizing your dose so maybe you should ask about that because you could need a split dose…i did.

    2. DON’T let the clinic talk you into upping your dose without asking them to test you to see if you metabolize MD more quickly than the average bear. That’s really quite a high dose so no reason for you to be having w/d symptoms by noon. Split dosing is a pretty good option if you are a “fast metabolizer”. I’m sure the clinic would love to just arbitrarily raise your dose but remember what goes up, must come down (assuming you dont want to be on the stuff forever)and coming down is a lengthy and uncomfortable process.

      1. Really I am on 170mg and I would be ok for the next couple of days. 120mg, 130, it’s all pretty much high doses of methadone, not quite sure why you’re Feeling withdrawal symptoms so soon after seven hours of 120mg dose?? I guess you have a high tolerance.

    3. When I first started my doctor told me basically I would still use until I was at a stable dose and my body was use to the methadone . Basically transitioning. Eventually you’ll be use to the methadone and won’t be one bit tired and be on a strong enough dose that it will last all day and any opioid would be useless not having any effect as the methadone blocks out the urge and the euphoria

    4. I’m almost in disbelief I have the SAME exact story as you and I’m getting desperate! Have you gotten relief? I’m ok 110mg and timing and symptoms at EXACT.

      1. Talk to your Dr. About doing a split dose. Not all clinics do this(my clinic is only one of 2 in my state that does) but it is definately worth asking. If the clinic offers this option they will likely require to do a peak/trough(“troff”) blood test to check your metabolism rate (and since the federal government requires them to provide justification for sending more medicine home with you). I was in the same situation though, kept raising my dose, would sleep a bit in the am, started to feel ill shortly after my nap. My anxiety actually started getting WORSE with each dose increase because I felt like I would never get propped relief (not to mention I had to wait 2 weeks between increases at doses over 130). It wasn’t until I started splitting my doses that I actually found the relief I was looking for, and it wasn’t immediate either.
        When I first started splitting my doses I was at 160mg so I did an 80/80 split. Even at 80/80 I felt off an had withdrawl like symptoms and felt like I maybe needed an 80/80/80 (three times a day split with a higher daily total), it was still discouraging.
        I eventually started tapering out of frustration with the intention of switching an alternate medication, but what ended up happening is i actually started feeling better and stable at a lower dose. What was happening is that at the higher doses I was experiencing relief in the morning shortly after dosing, but at night side effects would kick in and they were VERY similar to withdrawl symptoms. I would get hot flashes followed by cold chills, extreme anxiety, and sleep disturbances. I am now currently taking 40 every 12hours(80 a day), instead of the previous 160 every 24 and feel great.
        I also want to note that before this experience that led me my current dose I was at a different clinic and stable on 110mg every 24 hours for 12+years without issue. It was only when I switched clinics that my dose needed adjustment. What happened was the 2 clinics used different brand of medications(one used brand name mallinkrodt methadose, and the other vistapharm methadone, both cherry liquid), and while they were both “methadone,” the way my body processed them was very different. One brand provided much higher analgesic relief and lasted longer, while the other had effects that were so subtle it was difficult to tell when you took actually to much. The difference was actually so notacable, and so many transfer patients complained of the methadone being “weaker,” that my doctor eventually started having random dose samples pulled and tested to make sure they hadn’t been tampered with and met established manufacture standard levels. Ultimately, no tampering has yet to be discovered(or admitted to) at this clinic. That is really another issue all together though, one i have seen a handful employees lose their job from over the years at my first clinic.
        My overall point in mentioning this is just that methadone is complicated, effects can vary from body to body and brand to brand(due to additives and differing balance of D and L isomers). All you can really do when taking methadone is work with your Dr. and find a treatment plan that works best for you.
        Best of luck and I hope all works out for you…. First thing first, though, ask about split dosing. Split dosing will not only possibly solve your high peak/early fall off issue, but you may find you just feel “better”. Methadone only has a window of 4-8 hours of analgesic relief so more frequent “lower” dosing may result in less pain issues through the entire day, instead of just a few hours in the morning.

      2. I wondered the same thing and I started at 30 MG. I was a heavy iv heroin user for over 11 years. Smoked it for a couple years before the iv use and popped and snorted oxycontin 80s and ate percocets before that. Morphine and dilaudid before that. So…I went all the way up to 190 mgs before I was comfortable. Was on that high dose for about a year. Then started blind dose titration 1 to 5 mgs every week. Now I have take home privileges and go to the clinic every 21 days. Soon I’ll have 27 and that’s the most we are allowed in this state. Anyway, I had to go down some because after being at that high dose and leveling out, I started getting drowsy and couldn’t stay awake. So I figured I was too high of a dose. I quit feeling drowsy at 150 mgs, but have continued to go down slowly because I do not want to be on methadone for my entire life. I attend meetings and have a sponsor and also have a counselor I speak to every so often from the clinic where I get the methadone. So methadone isn’t meant to be a stand-alone cure all for addiction. But in concert with other therapies…support system and coping skills to help you not end up back out there runnin’ and gunnin’. Good luck hope this helps.

    5. You need a split dose. Have them do a peak and trough test. Your metabolizing your methadone faster than normal id guess

    6. You need take home meds. If I were taking it for pain I would go to a dr. After 8 hrs. At home I feel with drawls too. I take 1 10 mg. Every 6 hrs. Now. Since the new laws. I tapered down from 60 mgs. And had with drawls doing that. But leveled out.

    7. I was doing the same thing. They kept upping mine until I got to 175mg and I’m a pretty small sized girl. Turns out i was metabolizing it too fast so after almost a year of waiting my split dose finally went through.

  16. I am a 260lb 63 year-old white male diabetic (BG averages 150). I have been on and off of narcotics since 1979 when a car wreck messed me up. My primary injury at that time was removal in the wreck of my entire left femur, a left TBI and was in a coma for 42 days. I spent the next 2 years in the hospital and the next 20 years in and out of hospital trying various forms of rods, allografts and cadaver grafts after a nasty osteomyelitis from a 1982 surgery led to eventual above-knee amputation in 1999.
    A neuroma developed at the distal L5 nerve amputation site which left me in chronic pain and unable to wear a prosthesis to this day. For several years I got around well on crutches.
    Then in 2003 I fell down a stairwell and dislocated my spine at C6-7. Surgeons refused to do the necessary surgery due to the ongoing osteomyelitis for several years.
    Finally in 2005 they did the cervical spine fixation surgery and my heart quit in the middle of the operation. They had to stop the surgery incomplete and get me pumped back up, then do a CABG (quad bypass).
    They never completed the cervical fixation procedure so now I have a second source of chronic pain radiating from my c-spine.
    I was, over the years, on a variety of opioid pills graduating as I became opioid tolerant to fentanyl in the forms of extended-release Duragesic patches and immediate-release Actiq suckers. These covered most of my pain but made me a zombie, sleeping all the time. 18 months of that and I was useless, so I had to decide to either get sober and healthy or kill myself. Dying didn’t seem like a good option so I threw all my fentanyl patches and suckers away and came off all pain-killers cold turkey without even telling my pain management doc. Yes, that was dangerous and stupid but it beat the only other alternative I saw, which was a one-way fishing trip. Let’s just say that the next four months were no fun, but at the end of that time I was drug free and had my brain function and life back. I hurt like hell, but it seems the trade-off is being in pain or giving up mental functions that I kind of enjoy!
    I was drug-free for three years, then fell while deer hunting by myself deep in the woods where no one knew where I was when a crutch dropped into a deep hole where a stump had rotted out and the crutch bent in half, unusable. I was about a mile and a couple hundred yards downhill from my car so I had to slide along the ground backwards pushing with my good right leg. No fun at all.
    I went to a different pain management specialist who put me on a gradually escalating dose over 10 years until I was taking 120md/day ER and 40mg/day IR Morphine Sulfate. That medicine held me at the perfect balance of mental function yet adequate pain management for years. I think I was on that dose for four years.
    Then I moved from AL to PA in 2016. My new Primary care doc continued me on that dosage but sent me to a pain medicine specialist for all pain-related treatment. He kept me at that same dose from 2016 until four months ago. Then he claimed that new PA law now prevents him from prescribing more than 100mg/day total Morphine Sulfate. He offered to cut my dose to that level or change me to Hydromorphone 8mg every 6 hours. He said the 8mg/4*day hydromorphone was the equivalent of the 120 mg/day Morphine I had been on so successfully for years. It was not. I tried it for four months and it’s back to the roller-coaster effect I had 20 years ago with pills like hydrocodone, where I got decent coverage an hour after taking it then a decent effect for 3 hours then a sharp taper down till the 6th hour when I could take one again. It’s literally comparable to life on a roller coaster if graphed.
    So today he tells me that “changes to PA prescribing law” are making him cut back on hydromorphone total daily dosages, the same thing he had said previously about morphine…I can cut back to 8mg/3x day instead of 4x day, or he can change me to Methadone 5mg q 8 hours and in 5 days move up to 10mg q 8 hours. Basically what I interpret from the man is that he’s willing to change to most anything but he’s being limited on how high the dosages he prescribes can be. I don’t know if that is truly new law or if he got in trouble with the state and is being closely monitored or what is going on.
    So, tomorrow I stop the Hydromorphone 8mg every 6 hours and start 5mg Methadone tablets every 8 hours, then in 5 days move to 10mg every 8 to 12 hours as needed.
    Do you see any problems here? Will I again suffer withdrawals because of the abrupt change? I need another doctor to tell me if this is a sane and effective course of treatment but we only have 2 pain management specialists in PA and the other is 5 hours away. Any ideas will be appreciated.

      1. This is true, but with the ”opiod crisis”going on- which in my opinion is total BS, the only crisis I see is the one being initiated by our own government that is coming down hard on PATIENTS mind you, not prescribers, but patients who are now considered addicts, turned away from ERs with the coined term of ”drug seeker”. Excuse me, someone needs to put responsibility where it is warranted..the physicians. Drug companies like Pfizer are getting nailed with law suits, and why? Because they lied? No, they told the facts, maybe with less emphasis on negative side effects but come on, who are they providing the information to? Physicians who know exactly what opioids do, they know what side effects to watch for and the risk of addiction. They went to school for how long? Were educated on what? Drug reps aren’t responsible for the 25yr old that broke into the local pharmacy to obtain the drugs he needed for his addiction, instead the blame belongs to the VERY educated doctor who continued to prescribe said patient an ever increasing amount of oxycodone and then- out of nowhere, tell said patient- sorry dude, you’re a drug addict and you need help if you can’t stop taking the medication that I told you to take for 5 years. You cooperated and were a compliant patient, so now I’m punishing you for it. And. I really can’t explain why you can’t have it any longer. It has less negative side effects than Tylenol or Ibuprofen. The combination medications are somewhat comparable to the side effects of over the counter pain relievers..and that’s because they contain OTC medication that has a synergistic effect when combined with a synthetic opiate such as hydrocodone (the synthetic opiate ingredient in Vicodin). Oxycodone taken alone has great results for pain relief and when used appropriately, is much safer than OTC versions of pain relief. Maybe it’s that horrible side effect listed that makes the law come down on it..”Euphoria” is a side effect that must be squashed and removed immediately from the shelves. What havoc may be brought upon us for the risk of feeling euphoric…oh my.. Seriously! Yes, it has potential for abuse – hell ya I wanna feel good too..but most people understand moderation and abide to the instructions as listed. Just like we do with alcohol or chocolate. Moderation is key and we all over indulge occasionally. So what!? It happens. Don’t take ten oxycodone and decide to fly down the freeway (for some reason, every delusional person who has no idea of the real side effects of drugs truly are, believes they must make those indulgers think they can fly.. Think about it..every educational film about drugs before 1999 shows the ”high” individual attempting to fly… Why is that? I’ve always wondered. Anyway, my point is- why are opioids being treated as a detrimental, life ruining, people running amuck confused, evil, and soon to commit a theft of something horrific? Or is the real reason possibly the government wanting to profit from this market, they are the biggest drug dealers after all, and reducing supply means the demand will escalate, making crime inevitable and the beds remain full at the now privatized prisons whom profit off the inmates. We have more non-violent crime incarcerated (victims) people than any other country in the world I believe I heard recently, if not the highest, very close to the highest, I don’t want to state something that I’m unsure of so don’t quote me but look at our nation, land of the free? What a joke. And I would sincerely like to know who can tell me why opioids are being blacklisted. We need to use our heads and recognize that something is very wrong with this supposive ”opiod crisis”. IT DOES NOT EXIST. And those pointing fingers need to reset the alignment and focus on putting a stop to this. The big pharmaceutical companies applied this exact scenario to the costs you pay for said opiate prescription. They weigh it out..hmm, if we get sued by 30% of prescribers and lose 75% of cases initiated against us- we still profit by 2 billion. Carry on, just a minor setback.. Who gains in this situation? Well I know the county I reside in is suing big pharma..winner winner chicken dinner. Our government deserves a pat on the back. They somehow always come out on top.. Is euphoria so terrible for the hard working residents of our country? Maybe they deserve a pat on the back for once?

        1. Okay you are so wrong. I am a medical professional. There is an opioid crisis. Allow me to explain what has happened. In medicine we have something called OSHA and JACHO, also known as the joint commission. About five years ago they decided to include pain as the 5th vital sign. Ask any nurse or doctor how they feel about JACHO…anyhoo, due to “patient reviews” and complaints, it was felt that pain was not being managed well enough by doctors/medical professionals, so JACHO made the rule that pain now had to be the 5th vital sign, along with blood pressure, pulse, etc.. So, if you are having patients have major surgery in a hospital and they are receiving heavy duty doses of dilaudid, morphine, and fentanyl, what happens when they go home? You guessed it. They were going home with 3-3 weeks worth of Narcotics of just about any choice. When the Narcotics ran out they would call for refills and that is where there is a slippery slope. Most surgeons would turn them away, leaving them to ask their primary care docs. If the primary care docs said no, then patients had two options: find a pain specialist or buy the meds on the street. Pills on the street cost a cool $40/pill (according to patients) and most are taking 10-20/ day. That is extremely expensive for the average individual. That is when most turned to heroin. It is cheap, available, eases, and the pain. It also ruins your life. This is when we started seeing people on the side of the road slumped over high with car seats in the back of their minivans…this is a crisis. You are misinformed.

          1. Yes, but the majority of overdose deaths are from Heroin/Fentanyl, not pain pills. I’m a cancer patient. I’ve had a lot of radiation, chemotherapy and surgery. To say I have chronic pain is an understatement. My oncologist and his associates are discouraged from writing any type of opioid script. Primary Physicians won’t write them at all and send all their patients with chronic pain to pain clinics. The pain clinics do not manage pain, they taper everyone on opioids, off opioids. So that leaves the Chronic pain and cancer patients with 3 options: suicide, which is happening at a record clip, buying illicit opioids from the street, or getting into an addiction clinic that offers MAT or Medication Assisted Treatment. I know many, many chronic and cancer pain patients, myself included who now go to these places. I take Methadone, a moderate-high dose. I get this liquid every morning and I have my quality of life back. I tried the safer of the two drugs you had to choose from: Suboxone. It stopped the terrible withdrawal symptoms that I had from being cut off my pain medications from the cold Drs who didn’t care even a little bit with how terrible I would feel. But the Suboxone did not help with the cancer pain that still remained. So I asked the Dr there to switch me to methadone. It helps with pain more than suboxone. I can function and have some quality of life. It’s sad that I, a person who does not consume alcohol or co some, heroin or any type of street drug must go to an addiction clinic. Where the police squat in the parking lot every morning and hassle the patients, arresting them for silly things like smoking cigarettes. Apparently it’s illegal to smoke in the lot. I’m treated like a lowlife and why? Because I had cancer and had the audacity to not want to live in horrible debilitating pain every hour of everyday. What our government has done to people with intractable pain is despicable. There’s just no other word for it. The government is doing this to fill prisons and remove the dregs of society. . Most chronic pain patients are elderly or living on Socisl Security disability. By targeting them, they drastically increase the chances that these people will commit suicide, overdose or end up in prison. Any one of these things occurring would remove said person from the social security dole. The society as a whole would become younger and healthier and politicians could take credit. This is not Nazi Germany of the 1930’s this is the USA in 2019 and it’s really happening. Shame on our physicians for going along with and facilitating this farce!

        2. Doctors get almost ZERO education on pain and pain mgmt in med school, so you’re wrong about that. They are trying their best but the CDC produced that ridiculous “recommendation“ in 2016 (which they’ve since recanted) which was written by a “private” group of “experts” some of whom have buprenorphine patents and addiction treatment centers to feed (Looking at you, PROP/Andrew Kolodny!). Docs are stuck between a rock and losing their licenses until this opioid hysteria is resolved. Give them a break!

    1. Methadone is a wonderful, long-term drug for addiction & pain. I think you will like it because you won’t feel like you’re on a roller coaster ride anymore. It lasts a long time in your system, so there are not these ups & downs like with other pills. Good luck!!!!

    2. I wish someone had warned me off methadone before I got started. Do some research before getting eaten up by this awful drug. While the withdrawal for opiates such as OxyCodone and similar is about 7-10 days before the worst has passed, methadone withdrawal is MONTHS long. It’s due to its long half life – it will get into every fiber of your being and withdrawing is sheer misery. Been there, done it, and even with the help of Buprenorphine, I just wanted to die. Not sure about the laws in PA but pharmacies nationwide (Walmart and you can get other big box pharms will follow suit) are drastically reducing the amount of morphine equivalent doses of methadone they will dispense, which will only leave you with the option of going to a methadone clinic to obtain a higher dose and that’s just another expensive, time consuming nightmare. Our local clinic is up to $18 per day and no insurance accepted for it. Really, do your research before making this move.

    3. I have been on methadone for a week on a split dose of 15mg in. Am and 15 mg 12 h later have missed. Dose do to the hospital not sending my records to clinic i have call the hospital and the methadone clinics as still nonothing i mean i have sweats. They have also call cps and flu my son to icu due to the methadone and herion in his system. I feel as i have made a bad move will i lose my son

  17. On methadone for chronic pain for over 10years. Tapered to 40mg total daily & 10mg oxycodone for breakthrough pain. Dr said i had to STOP methadone, latest ekg showed prolonged qt. Ive never had a bad ekg before. Switched me to oxycodone 30mg 4x daily. Am scared of withdrawal & afraid pain will get worse. Is this dose a good equivalent?

    1. This conversion should be done VERY slowly, as one is tapered and the other is slowly added. Doing it as a straight conversion is very dangerous because not all patients handle these drugs the same way.

  18. Hi. Thanks in advance. I am taking 110 mg liquid methadone daily. How many 10 mg tablets per day would be the same? I don’t think it would be 11 tablets would it?

      1. They should close down all these methadone clinic in Chicago if u drop dirty they still give it to you it’s a disgrace

        1. that’s because these are addicts and they relapse… It happens so what happens if they didn’t dose them or kick them out of the clinic? they will just go by there illicit drug of choice and then they’ll have a total relapse and never come back to the clinic so what good does that do?

          1. Like Dr.Jeffrey Fudin said, “It is not a law”! There are new guidelines, but they are not new laws.I do not agree with the your negative comments on methadone! If you take it as prescribed you will not experience any withdrawal! I have been on it for years and my experience has been vert positive and it has helped me more than anything else out there! Also, in some places, like where I live, there are clinics that take insurance, and if you do not have ins. you can qualify for free treatment! Good luck!your exactly right!

          2. they are going out and doing their drug of choice anyway, so what good is the clinic doing them in the first place?

        2. Very ignorant and misinformed comment. Not trying to be mean. Yet you must study addiction and treatment more closely. It sounds like you know nothing at all about addiction other than biased perspective which may help you but not others. Don’t be so hard on something you have very little to no understanding of.

      2. Methadone for Spinal Arthritis for 15 years ,started at 80mg / day. Since new guidelines I have been cut ( slowly) to 60 mg / day..Is this a large dose? Seems as if my pain has increased. What is the Mme for 60 mg / day.? Thank you.

          1. I have a question hoping for an intellectual reply.If there is a patient that has been taking 85 mg’s of methadone for a 9 year period and has been successfully stable then asked to switch to the brand name liquid form of methadone but can not metabolize it well at all .What would be your factual conversion do to this patients metabolic profile.
            A.Do you think it’s wise to interrupt patients long stretch of stability or,
            B.Should thy patient be left taking what is best suited for his metabolism so instability is interrupted

            Thank you…..

    1. Methadone is available in different mg tablets, but it has been my experience with others I know ,that a Dr will not provide the same amount in tablet form as they do in liquid, since that is a large dose they would probably work with you to find the amount that would keep you comfortable, as tablets are given 2 to 6 times a day instead of all at once.

  19. Hi Dr. Fudin, thank you for what you’re doing here. You’re helping so many people! Even those in Europe who just read your website for support/information 😀

    I have a problem with chronic opiate addiction and heroin use, but I have never abused methadone. Currently I am using approximately 125mg brown heroin, in doses of 10-20mg evenly spaced throughout the day as needed (I have a proper milligram scale, I weigh out my doses exactly). I have done so for almost two weeks now. A few months ago I read on a forum that you can quit heroin without any withdrawal symptoms if you use methadone to taper. This is the blog post I found:

    The thing is, last year around October (2018) I had been using 100mg of heroin daily for exactly 19 days when I started the methadone taper. 12 hours after my last heroin dose, when I started feeling withdrawal symptoms, I started taking 10mg of methadone every 2-4 hours until I couldn’t feel the withdrawal anymore. It quickly became apparent that I needed about 30mg of methadone per 24 hours to prevent almost all withdrawal symptoms. I write down all drugs/medications I take and this is the taper schedule I ended up using:

    29-09-2018 19:11 10mg
    29-09-2018 20:43 10mg
    30-09-2018 1:31 10mg

    30-09-2018 19:19 20mg
    30-09-2018 22:57 10mg

    01-10-2018 19:12 20mg

    02-10-2018 16:30 10mg
    02-10-2018 21:15 5mg

    03-10-2018 16:50 10mg
    03-10-2018 21:28 20mg
    05-10-2018 19:45 20mg
    05-10-2018 20:45 10mg
    05-10-2018 23:20 5mg

    07-10-2018 16:30 20mg
    08-10-2018 17:15 10mg

    As you can see, at first I tapered too quickly. But now the thing is; it worked. Other than some mild sweating that would come on suddenly out of nowhere I experienced no withdrawal symptoms whatsoever. Even the weeks after, nothing. I have searched online as to how this works but I am having trouble finding any real information on this. Do you have any insight as to why the methadone might have alleviated my withdrawal symptoms and more importantly, why the withdrawal did not come back after stopping the methadone? I have detailed logs of my heroin usage in the preceding weeks that I can send to you if needed.

    Thank you for reading. I hope to hear from you soon 🙂

    1. Ron, Methadone works because it uptakes and occupies opioid receptors which in turn normalizes the central nervous system balance of noradrenalin. When chronic opioids are abruptly stopped, or tapered too rapidly, the neurophysiology of the brain does not have time to readjust. A simple explanation is the following…
      1. Acute opioids cause drowsiness because the diminish noradrenaline (NA) release in the CNS (NA generally causes hyperexcitability or wakefulness)
      2. With chronic opioid use, your brain adjusts to make more NA so that continued exposure to opioids doesn’t leave you tired.
      3. Abruptly stopping opioids now leaves nigher amounts of NA because the brain doesn’t have time to adjust NA production downward. Now you are hyperexcitable and have massive amounts of NA – that preents as withdrawal, THEREFORE, and other way to treat withdrawal is with
      4. Clonidine, which is a centrally acting alpha agonist, which in lay terms is and antihypertensive drug that blocks NA receptors.

      For a relatively easy read and more comprehensive explanation, see Kosten TR, George TP. The neurobiology of opioid dependence: implications for treatment. Science & Practice Perspectives. 2002 Jul;1(1):13.

      Now I’ve got a question for you! Without providing any specific, how in the world does one obtain morphine, heroin, and methadone if you are not under the care of a physician? And for the record, YOU SHOULD BE TREATED BY A PROFESSIONAL. DOING THIS YOURSELF CAN BE PHYSICALLY AND MENTALLY DANGEROUS, including harm or death.

      1. I’m actively working on being opioid free. I have been on some form for years 18 years. The latest dose was 120mg/methadone every morning. I’ve tapered down to 15mg/day and have an appointment for a buprenorphine intake in 6 days. I was hoping to use this method of switching and that using a partial opoid would be easier to fully taper from a lower dose.
        I took my last dose of 15mg on 3/19 and have 18 20mg oxycodone (light green, round, epic pharma stamp E 7) and 9 15mg IR morphine to get me through the week. My questions are…
        1) Would it be possible to completely taper off opioids comfortably with what I have and forgo the buprenorphine entirely?
        2) What’s the longest the last dose of methadone would be in my system? As in should it be out by tues?
        3) Should my PCP be afraid of prescribing a short acting benzodiazepine for the duration of the transition for sleep?
        I can’t seem to find any literature on these specific issues- aside from drug prevention propaganda.

        1. Benzo are very dangerous during this transition. To blunt withdrawals your doctor can prescribe clonidine or Lucemyra. Methadone can stay in the blood 7 days to over a month – it is highly variable depending on genetics.

          1. So would it be theoretically safe to begin buprenorphine if methadone is no longer present in a urine test? If the goal was to avoid precipitated withdrawal?

        2. Jilly I have been in your situation many times unfortunately.
          If I was you I would continue to taper off methadone reducing 1mg every 5 days or so. If this is not leaving you feeling withdrawals maybe 1mg every 3 days. Just make sure you don’t start suffering by rushing things.
          When you get to 5mg you could try 1mg a day then that should be that.
          Just to clarify in the UK methadone is in liquid form dosed 1mg per 1ml of solution making tiny dose adjustment easy.
          Basically at such a low dose, switching with tablets to then switch to another product is a lot of messin arou at such a great point that you now are.
          When I have done this way with small adjustments I’ve been able to come off with zero issues or withdrawals whatsoever.
          Wishing you all the best, I know it’s a bit old now so much love from the UK.

          1. thankyou. do you know how long methadone keeps blocking opiates after last dose?i ve been on methadone for years for chronic pain. now my docyor switched me to morphine I feel like hell. will it take weeks for the morphine to start working and the methadone not blocking?

        3. Have you ever tried Kratom? Check out the Netflix documentary ‘A Leaf of Faith’. I can only speak for myself and what I’ve heard from other people, it really does work.

      2. Good point, also, unless he is in Europe, how in world does he know how milligrams of Heroin he is administering? My question to you is regarding the increase in the brain with concurrent opioid use. Does this also suggest that the concurrent use of sympathome.tics while treating long term pain with pure agonists, will reduce sympathetic outflow when opiates are withdrawn: by reason of feedback inhibition of reuptake of NE?

      3. hi im taking 100 mg daily of liquid methadone. whilst still in pain, i was also prescribed 5mg bupenorphine patch that stays on for a seven day time frame. do i need to worry about a fatal interaction? im a bit sedated but finally no back pain. thanks

          1. The DEA shut down my pain management doctor two weeks ago. I went into severe withdrawals. So a friend told me about a methadone clinic. I have been going to the methadone clinic for one week. My family doctor I saw yesterday is going to get me into a new pain management doctor. Will the methadone show up in my urine test as methadone? Or will it show up as oxycodone? I am afraid to tell my new pain management doctor that I had no choice but to go to the methadone clinic. Thank you for reading my question. I feel like a leper because I am in chronic pain I’ve already had seven surgeries and need at least two more before I’m done and then I want to get off at this pain medicine as soon as possible because I’ve already been on it for 10 years and I’m scared the government is going to make all pain medicine totally illegal in the future anyway.

          2. Stacey, Methadone will show up as methadone (if tested). You need to be honest with this new doctor up front, otherwise you’ll be right back in the same boat when he/she finds out, and perhaps even worse off because you were dishonest and it will be reflected in your chart and follow you around.

          3. Hi,
            If I start reducing 20 mg methadone by 5mg every two weeks at what dosage of clonidine should I ask my PCP? Taking pills so too hard to deduce by 1mg every two weeks? And, how long on Clonidine wd symptoms? Thanx!

      4. Ok this has nothing to do with methadone But i didn’t know how to ask a question so here goes my son is 29 years old he suffers from a rare kidney disease called Loin Pain Hematuria Syndrome ( its like passing a kidney stone 24/7 ) his pain management doctor put him on Percocet 10/325 and 150 belbuca twice a day Will the belbuca make the Percocet not work properly

          1. How can one use bupe and Percocet at the same time?bupe has a higher binding affinity and would instantly remove all full antagonist s from receptors causeing instant withdrawal… also while clonidine is better than nothing its effects to dull withdrawal from any long term iv opiate addict is like a band aid on a compound fractor

          2. Oxycodone does not remove buprenorphine from receptors. Once bupe occupies those receptors though, there are less receptors available for oxycodone because the bupe is bound so tightly.

        1. Donna,

          Im a 37y/o male from Scotland, and after losing my left kidney, i have LPHS in my right, daily bleeding, and absolutely hellish pain, its horrific.

          By contrast, and bear in mind Scotland is different, i use 40mg Oxy 2x per day, and up to 6 10mg short acting oxycontin-it seems to work ok, but when it gets really acute, theres little that can be done, its just that painful. One thing i did try with mine, is something called Diclofenac. It isnt an opiate, but added to the opiates it seems super effective vs our type of pain-i think it belongs to the NSAID family-knowing his pain, its worth adding in to the mix.

      1. No, morphine and oxycodone do not stay around for more than 3-5 days after last dose and there is less variability from patient to patient compared to methadone. But, buprenorphine will predominantly occupy the receptors and precipitate withdrawal similarly with all three, methadone, oxycodone, and morphine.

        1. Thank you so much for all the great information. I’m truly amazed at the new drugs like lofexidine. I brought it up to my Dr but knowing the reluctance to prescribe new drugs in the addiction medicine field (like vivitrol and buprenorphine) and just how long they take to “catch on”…I’m not hopeful, but for the generations to come- it is very optimistic. Although this is the trend that seems to cause overdose, lower quality of life, and perpetuates chronic pain.
          It will be lovely if we can live in a future that all physicians actively take interest in treating addiction and upholding the oath to (truly) first do no harm. Separate the stigma of addiction, curtailing government involvement in practice, and supporting patients with chronic pain.

  20. Dr. Fudin, I took your advice and I went in after 5 days without anything for withdrawals. My cramps in my stomach were bad . I took your post on Clonadine and that’s what they gave me. The only problem was, it caused terrible dry mouth. So they gave Dicyclomine HCL 10 mg. It’s for severe stomach cramps It made a big, big,difference. I wish I had found your web sight ,7 months ago Thanks, Dr. Fudin.

      1. So I’m 105 lbs 5′ tall ….I took 3 5mg pills 3days ago how long will they stay in my system?

      2. Also, what can I take for severe leg cramps and sweating during the night while detoxing from 20 mg of Methadone? TY

  21. Dr. Fudin, I have been on methadone for pain for to long. I new after 6 years I need to get off and suffer with the pain. I just couldn’t past the ideal of getting off. It took 4 more years and a grandchild. My Dr. started me on a dose of 70 mg.. I asked to taper down to 30 mg. I went back to 60 mg until I heard the good news. I went to 30 mg my next visit. Surprisingly, it worked as well as the 60 mg. After that I went to another Dr. and asked for help get off it. This Dr. dropped me 20 mg and 10 days later a drop to 17.5 mg and 21/2 deduction each month until now I’m off. I have been off 3 1/2 days and the with no methadone. I have to admit it is uncomfortable and I have lost 30 lbs. How long can I expect this to go on. My Dr. said come back in a month and keeps pushing medical marijuana but I told him it doesn’t help and stopped taking it. I found the cbd oil helped more the med marij’ I told him to cancel my licence for medical marij. For those who want it, better have money. My Dr.wanted almost $1000 over 1 year and $40 a month cash. That’s the cheap part. Wait until you go to purchase it. I quit after 5 months. “Now Dr. Fudin, the question for you.” How long can I expect to be going through this?” Its been 5 months of uncomfortable time, but I’m off 31/2 days and I lived through it. Please get back as soon as possible if you can, Thank you

    1. It’s hard to predict how long you’ll have withdrawal. But, your doctor should be kind enough to give you what really works to prevent withdrawl – clonidine or Lucymera. The latter is relatively new and only FDA approved for acute withdrawal. Clonidine has been used as a standard of care off label to treat or prevent withdrawal. This is a discussion you should have with your doctor. Marijuana does not prevent withdrawal, although it may make you care a bit less about the symptoms.

  22. Dr. Fudin, I was on Methadone for 9 years for pain relief. 23 years ago I was 4’8″ 300lbs. I was one of the trial Roux en-Y Gastric bypass patients on 11/19/96. I went from that size to 79lbs 4’11”. I was 25, obviously I didn’t have a growth spurt. Eventually I evened out at 95lbs and have stayed around that for the last 21 years. I got pregnant with my first son at 32. No problem until delivery, they left him stuck in the birth canal for almost 40 hours with NO MEDS! anyway, after I had him, my back pain was so bad I couldn’t walk. They put me on liquid Morphine. DIDN’T like that AT ALL!!! Switched to Norco 5/3.25. OK. Then SUPRISE I get pregnant with my youngest son and OB/GYN says “Can’t be on Norco while you’re pregnant.” “You need to go on Methadone. Never having done illegal drugs was not familiar AND trust my doc. Anyway after 9 years I was up to 190Mg. Jan 1,2019 I started self detoxing. I cut down from 190 to 45 for about 2 weeks, then cut down to @ 10m for about a week then quit. I would take 1-5mg every 5 or so days when withdrawls got bad. Now it’s 2/15/19 and some days symptoms are so bad can’t get out of bed. Need to be able to work 7 days a week/12 hours a day. I am now getting ready to start CBD:THC 1:! ratio for withdrawls. Good idea??? PLEASE RESPOND ASAP as planning to start in 2-3 days. THANK YOU!!!!!

      1. Hi dr Fudin,

        I have been in methadone for 8 months now, I am 41 and have tapered down from 50ml methadone once daily down to 21ml. I tapered down 2ml every week until I got down to 25ml and am tapering 1ml every day atm. I would like to know a safe and fairly pain free way to taper when I get down past 20ml. Is 1ml daily too much? I’m a recovering addict and am determined to live free and clean. It’s just I need to be able to function in my job.

        Also I am due to have some dental work carried out under sedation using midazolam. Does methadone effect midazolam ?

        Thank you very much

        1. Jael,

          I cannot answer your question for a number of reasons, not the least of which is not having access to your medical record. Also, milligrams, not milliliters is the important measure for dosing. Yes, midazolam is very dangerous with methadone or any opioid, but if its in a controlled environment with a doctor that knows you’re on methadone it should be okay because midazolam has a very short half-life. But, I’d stay around the dental office for a couple of hours after the midazolam at least.

      2. Hi Jeffrey ,

        Question please i was taking 160mg daily of oxy time release i just got switched to methadone . How many mg would i need to equal close to 160mg oxy i know its all different but any ballpark figure can help me please thank u

  23. I was taking 90 mg of methadone for 8 years for complex regional pain syndrome. With all of the opioid witch hunts, my doctor has me down to 60 mg of methadone per day and my pain level goes up markedly each time he drops my dosage. He tells me he has no choice but to do this. Could he add low dosage of tramadol to help with the breakthrough pain?

    Thank you so much!

    1. Robert,

      Tramadol would be totally inappropriate for several reasons. He could add tapentadol on an as needed basis. If, as the methadone continues to decrease, the pain increases, he could add memantine (used for alzheimer’s usually). Let me explain. Both memantine and methadone have a unique property to block NMDA receptors – these are responsible for neuropathic pain. Print this out and bring it to him with this, Zorn KE, Fudin J. Treatment of Neuropathic Pain: the Role of Unique Opioid Agents. Practical Pain Management. 2011 May; 11 (4): 26-33.

    2. I’m on the med reduction train too, from 10mg 3x/day to 10mg/2x a day. I can see now, comparatively, it’s a rather low dose. My pain & fibromyalgia flaring has skyrocketed between the 12 hour gap. I think the CDC needs to stay out of my business with my doctor!!
      Good Luck all!!

      1. I thought that no opiates worked as methadone is a blocker for opiates? Am I wrong? I took Vicodin after taking methadone and got no effect at all… well at least no “ high”

          1. Your wrong methadone does block other opioids .u can not feel them right ..I know I been on .methadone and oxycodone for 20 years i just was switched over from 40mgs of methadone to 20 mgs of oxycotin 2 a day ..which withdrawal is a bitch .but the whole time I was taking the methadone on 85 mgs a day I could not feel the 30mg of oxycodone ever if I took 4 at a time

          2. Jamie, There are other reasons for your experience, but blockade of opiate receptors is not one of them. If you have interest in this and are good at science, I suggest you go to a medical library and read Goodman and Gilman’s Pharmacological Basis to Therapeutics.

  24. Hello, I have been taking 2 10 mg oxycontin ER and 4 10 mg oxycodone instant release for over 10 yrs now. With the new changes to the rules my DR has prescribed me 2 5 mg methadone oral pills per day with 3 10 mg oxycodone per day for break through. I don’t like the stigma of methadone and now I am nervous about the interaction of the two meds. What are your thoughts.

      1. I was taking 120 mg of methadone a day and 40 mg of Valium. I am tapering slowly off the methadone now down to 85 mg a day. Why have I never had a drug interaction.

      2. Jeffery,
        Is their a problem with dosing if you take 30 mg at 10mg tid or 5mg every 4-5 hours. The 4-5 hours works best for me and has for years.

        I have been taking methadone for about 20 years for chronic pain being seen by pain management specialists. Prior to that I took OxyContin but had no problems changing over to methadone. The benefit to methadone is it can be cut in half when needed but oxy can’t.
        Because of the government shutdown on opioids doc had me change from 60 mg tid a month to 30 mg a month for 2 months. I was suppose to do 10 mg tid but because of pain took 5 mg every 4 to 5 hours. I can manage that. Now I’m down to 20 mg bid I’m doing 5mg qid. After 4-5 hours my hands and feet burn more. I have feet burning syndrome so I take Gabapentin for that but the methadone withdrawal makes them burn more.

        Also anything else help for chronic pain.

  25. I have been on methadone 40 mg daily for 15 years, for severe chronic pain. Now because of new regulations, and my doctor retiring, nobody will prescribe it. I found a doc to switch me to oxycodone er 40 mg daily -taken 20mg bid (after a very awful wean from methadone.) I was doing well before all this. I am a good mom, wife, and person. I had as normal of life as a person in chronic pain can have before this. Now my pain is totally out of control. Then on Tuesday, doc prescribed tramadol for breakthrough pain. It is like speed to me. It dilated my pupils, made me jittery, anxious, and unable to sleep or eat. And that was just 1/2 a pill (25mg.) I have always been very sensitive to drugs, and have had adverse reactions before. Cymbalta was prescribed for pain, and I got the “suicidal thoughts” reaction. Same w/ lyrics… I feel like a guinea pig… I think we just need to adjust dose of oxycontin er, but I’m waiting to see doc next week. In the meantime, I can’t walk -too much pain. I’m in Michigan’s upper peninsula, and it was -25 this morning. Among other issues, my femur is bone covered in metal, encased in more bone. Even UofM declined my case- twice. Nothing can be done. Just manage the pain… But it’s not managed. Not like before. I feel like a shell of myself, and my kids and husband want me back! I’m constantly in pain! Trying to stay hopeful.

    1. Angie, Methadone is very different than oxycodone in many ways. For example, in addition to the opioid activity, it blocks NMDA receptors. If you can’t tolerate tramadol, it doesn’t surprise me that you had problems with duloxetine, because both inhibit reuptake of norepinephrine and serotonin. It also make absolutely no sense to be on tramadol when you’re on that dose of oxycodone. Tramadol has thousands times less the binding to the same receptor where oxycodone works. A comparison would be a single drop of water placed into an olympic size swimming pool. See Zorn KE, Fudin J. Treatment of Neuropathic Pain: the Role of Unique Opioid Agents. Practical Pain Management. 2011 May; 11 (4): 26-33.

  26. I have been on 4 Hydrocodone 10/325 per day or years for chronic pain.
    My new doctor has suggested to switching me to Methadone what is your thoughts on this. I always thought methadone was for heroin addicts. Will it kill the pain? How much Methadone do you take to convert your body from 4..10/325 Hydrocodone?

    1. James, Methadone is often an excellent choice for the right patient and can work as well or often better than hydrocodone. It is not for addicts ony – it s used for them because it sticks around in the body for a long time and can therefore be doses once per day while being observed in a methadone maintenance clinic. For treating pain it is generally does 3-4 times daily. it should only be prescribed by someone very experienced prescribing methadone.

  27. Short version of a very rough life. 3 serious MVAs. 1 in 1983 at 21 years old. 60 reconstruction surgeries til I got tired of them and never finished my face. 5 years rehab. Went back to college. Had career. Managed pain. Was rehabilitation service Director. Had PT do ultrasound on my back. . 1 in 2007 at 45 years. 7 surgeries. Never healed. Perment disability. Unyielding pain. Prescribed hydrocodone then oxicodone er and ir. 4 80s and 10 30s. 1 in 2011. 6 shoulder surgeries. Have thr, reverse total shoulder replacement, and rods pins and wires around spine. Permanent nerve damage.
    Dr. Got fired. They sent me 70 miles to ” pain Dr. ” LOL. Took me off everything. Bad w/d
    Even took away sleeping pill and Xanax. Oh and Baclofen used for swelling inside my vertebrae in my neck. Put me on suboxen. Had severe allergic reaction but I was so psychotic I didn’t realize it. The 3rd day on it to the 6th I was in a bad place. Ended up in er. Now he’s going to put me on .5 my of methadone 2xs a day. Isn’t that crazy. He must know it won’t work. Why drive 140 miles for .5 my. They even took away albuterol tablets. So my cold is acting up. 11 years on opioids, sleeping pills, antianxiety medication and I had no problems with respiratory depression. Now he won’t give me .5 methadone with zanex because this might happen. If it never happened on my old medicines. Why would it happen now.
    I am pissed. The government should not run health care. Fentanyl, heroin, street drug over doses should not be put in with pain medicine. It inflates the “crisis”. And people who need pain medicines should have them. They don’t even have a good assessment tool to decide who needs medicine and who’s gaming the system.
    I went from living with minimum assistance and ambulatingi to being dependant on w / c . i have no quality of life now. I feel like a lab rat.

    1. Dr fudin. The pain Dr who is in fact a internal medicine dr and new to pain mgmt to away my oxicodone. Prescribed me with Suboxone which ended me in er. He then prescribed me methadone. It is not helping my pain in the least. Am I being for irreparable chronic pain or an addiction I never had? My anxiety is threw the roof. How long does it take methadone to work? Is this a stain on my medical record? Does it look like I’m being treated for addiction? Will any physician ever treat my pain after this?

      1. Pamela, Methadone should oly be prescribed by a VERY experienced clinician. Methadone titration takes several days to weeks if done properly. The dose cannot be adjusted quickly because it accumulates (sort of sneaks up on you) and can cause death if not done carefully. If you have an experienced person prescribing it, he/she should know how to do it. It theoretically should not be a “stain” on your record, but some people see methadone and jump to conclusions. generally for opioid use disorder it is doses once daily; for pain, it’s generally in divided doses of 3-4 time per day. I cannot predict what other physicians will or will not do.

  28. Dr. Fudin,

    I have a very complex history of chronic pain combined with addiction. Going back to the year 2000 I was prescribed OxyContin before having surgery to correct some back issues. I have since had four other back surgeries, and have been on methadone maintenance treatment at a clinic since 2005 after difficulties weaning off the oxycodone products. The issue I have is that with over 10 years of compliant drug screens and clinic programs, because of the guidelines the clinic must follow, I still have to take my 100mg dose once a day instead of divided multiple times per day. Even though I receive a large number of take home bottles, I am not allowed to change the dosing frequency because if I have a call back for a bottle verification, everything must have been taken as ordered. Taking methadone q day keeps me out of withdrawal, but it seems that after 8 to 10 hours my radiating leg pain begins to return and lasts until my next daily dose. The expense of clinic attendance is also excessive, which I must pay out of pocket, whereas if a primary care or pain management physician could prescribe the medication, I could pay much less or be covered by insurance. I guess my question is twofold.. first, is there any history of patients with a history of methadone clinic attendance being taken on by regular prescribing physicians if they have been compliant long-term and also present with legitimate pain issues? Second, if leaving the clinic is not feasible, is there any way to work around once daily dosing to get better pain relief without violating federal or state guidelines? I live in West Virginia if this is relevant aside from the fact that the area is very rural and aside from the WVU medical center in Morgantown, there are no large clinical institutions like what would be found in larger cities. I appreciate your time and the excellent information and mathematical formulas you and your team have worked out for opioid conversions involving methadone. Being a practicing nurse in the 1990s before sidelined by back injuries, I can understand how rewarding it must be for you to provide such an innovative and helpful service for those suffering from pain. Thank you.

    1. Travis, here are the answers to your questions…

      Is there any history of patients with a history of methadone clinic attendance being taken on by regular prescribing physicians if they have been compliant long-term and also present with legitimate pain issues? It is against federal regulation for a physician that is not certified to prescribe methadone for “maintenance” of opioid use disorder to precribe methadone for this. A non-vertified physician can in fact prescribe methadone to treat pain. if your doctor has clear documentation of a pain disorder, he/she could prescribe methadone in 3-4 divided doses per day basically using your current daily dose and splitting it up. BUT, it would need t be made crystal clear in the chart that your doctor is treat PAIN, not opioid use disorder. It’s a very fine line that many doctors do not want to walk, but it would be legal if handled appropriately.

      Second, if leaving the clinic is not feasible, is there any way to work around once daily dosing to get better pain relief without violating federal or state guidelines? YES. You can have a frank discussion with your providers at the methadone maintenance clinic and discuss the dilemma. They are not required to write a prescription for maintenance once daily, although that is the standard of care. Just as outlined above, the docs in the methadone clinic cannot prescribe methadone for pain, but can prescribe for maintenance. Essentially it is the opposite of above. It is my personal belief that in a patient with a dual diagnosis, the law should allow for collaboration between the two clinics, but it does not.

      1. Thank you for your answers. I was not aware that maintenance prescriptions or orders could be more than once per day, since as you mentioned the standard of care is for once daily dosing, and all clients I have met also dose once daily. While hospitalized a couple years ago with an acute exacerbation of ulcerative colitis I was given IV methadone for maintenance three times daily due to me being NPO, but I imagine there are special rules for hospitalized patients after the hospital verifies the patient’s status and dose with the clinic. I do know that I had little noticeable back and leg pain during the 10 days I was treated that way in the hospital, but it is also possible that I was not noticing it due to the acute illness I was dealing with. There was a big discussion, though, about the conversion from PO to IV methadone, with the resident who was prescribing wanting to give a considerably lower dose than what the pharmacist recommended. The pharmacist felt that the PO to IV conversion was much closer to 2:1 or even 1:1 than the doctor who wanted to convert similarly to other opioids like dilaudid or morphine which are absorbed much better by injection than orally. The pharmacist’s recommendation was eventually followed after the attending physician also got involved, and I never dealt with any withdrawal issues during conversion, so apparently she (the pharmacist) was correct in her assessment. Is this also a complicated conversion process, when it is necessary for a person normally on oral methadone to take injectable methadone for some reason?

        1. Travis, Glad to here the pharmacist helped. They are generally more expert at opioid conversions compared to other clinicians. NO, the conversion from oral to injectable methadone and back again is a piece of cake compared to converting to/from methadone with another opioid.

    2. Travis and Dr. Fudin,

      Just a suggestion for Travis. Go to your clinic and ask them to do a Peak and trough . This will help the doctor at the clinic see when your high and low is with the methadone in your blood. As far as clinic doctors not being able to prescribe for pain, I know that’s the way it used to be. Since this opioid stuff started happening the doctors at my clinic have now begun to take care of the addiction as well as the pain. AS LONG AS ITS DOCUMENTED. I know this because I have been on methadone my self since 2002. Been clean ( only what is prescribed to me) since 8/19/2005. I have 3 herniated discs and arthritis and I have 13 day split takehomes. I was given a split because of my back pain. I take 65mgs in the morning and eight hours later I take another 35. It may be different in West Virginia but here in Rhode Island they have loosened up on the clinics prescription for pain. I hope this helps and good luck to you. Dr. Fudin thank you for all that your doing with helping people with opioid addiction and pain management!

  29. I live in Florida and am on 160 mg of methadone and I am moving to Tennessee and I did not have time to taper off because the move happened quickly because Tennessee you cannot go higher than 120mg so they said when I get out there they can’t give me more than 120 so am I going to have withdrawals from going down to 160mg to 120mg in one day they said they can do a peak and trough test but that cost money and the bencheley within the week they can have me up to 160 if the test says it’s okay what I would like to know is am I going to have withdrawals badly or just a little from going from 160 to 120 in one day

    1. Patrick, It is unlikely this will cause withdrawal and if it does, it should be mild. I suggest that you ask you doctor to provide colonidine or Lucymera on an as needed basis to blunt the withdrawal symptoms if they occur.

        1. Lucymera should work for any opioid withdrawal. It is FDA approved for abrupt discontinuation of opioids, but theoretically it could also be used for a more reasonable, slower taper.

    2. What part of Tennessee are you moving to cause I understand what it’s like. I moved to Georgia from Chicago and same thing happen.

  30. My understanding on methadone blocking other opiates is that the receptors are full. Doesn’t block other opiates Why would you want to take other opiates when on methadone anyway?!?! Seems like playing with Fire.

    1. Methadone does not block other opioids. Adding other opioids to methadone adds more opioid activity and could be dangerous and even life-threatening, and should NEVER be done without the oversight of an expereinced prescribing clinician where methadone is being used for chronic pain management.

      1. Then according to you, my pain doctor could very well kill me! I have been on Methadone for 30+ years and I have not been successful in getting of it. I am a chronic pain sufferer. How do I get this information to my doctor? My email address ( Thank you

        1. I’m also a chronic pain sufferer- I was on 30 mg of methadone daily for years and 40mg of Opana- until I changed to Medicare- I stopped the methadone cold and switched it with 30 mg morphine sulfate ER 2 daily and for breakthrough pain I switched to 10 mg Percocets 3x daily…You can make the switch- I just messed up my getting Tylenol in my pills –

      2. I’m on methadone I missed my dose an the take home we get for Sunday buy Sunday night I’m gonna be feeling bad I got 130 morphine I had saved just Incase of a emergency I guess it’s ok I just don’t want to go into withdraw ??

        1. When I was on methadone I could miss two days and be just fine. Maybe slightly a bit less patient and it took less to make me angry but no physical withdrawal symptoms at all. It honestly depends on a few factors. How long have you been on it? If you’ve been on it for at least 6 months, you shouldn’t experience any of the normal withdrawal symptoms. However, I have heard of people dosing one morning and they are sick before they get there next dose the next day. I could see that happening if you’re a new patient but not an established patient. Our minds are so powerful and can trick us into feeling bad and sorry for ourselves. I personally think you will be just fine darlin. I was on 175 milligrams of methadone and could miss two days in a row and not dose until later in the morning on the third day. I’ve been off methadone for five years now and if I could do it, I promise so can you. It wasn’t easy at all and it honestly took almost two years before I felt good again but now I feel amazing. Even better than I did in my early 20s. When I started weening down I started “clean eating” just google it and you can learn all about it. I started going to the gym every morning so my body could get use to releasing
          dopamine on its own. I started changing all my bad habits to healthy habits. Now I lead a Cross Fit class three days a week and a Yoga class twice a week. I look better than I did in my teens. My body is toned and healthy. I take supplements to help my brain because since I’ve been off the methadone I am very forgetful sometimes. For example, I can put my phone down and a few minutes later forget where I put it. You won’t truly realize how much damage the methadone has done to you until you get sober. I speak to women and mothers who are on methadone or heroin at a center on Tuesday and Thursday nights. When I stand in front of these women most of them stare back at me and they look broken, they don’t think they can quit the drugs and they don’t think anyone cares about them. Well I make sure they know that I care. If I didn’t I wouldn’t come every week to speak in hopes I got thru to just one person. Of course I would love to reach all of them but I’m a realist and I know that none of those women will get help until they have hit their own personal rock bottom. Most of the time after I speak I can see some hope coming back into these women’s eyes. They saw that if I can get off the methadone and have a good productive life they can too. I’m not special or any different then anyone I speak to or anyone reading this so I promise you, if I can do it so can you. It’s not easy, not at all but when you finally break those chains you will have a new lease on life and you will start to love yourself again, you will be proud of yourself and you will respect yourself. I’m going to leave my email address for anyone that wants to talk about getting off methadone and for anyone who just needs to talk about life in general. If you chose to email me I will tell you more about myself and how I ended up on methadone and all that jazz lol. My email is

          1. Jennifer, Thank you for your encouragement. The reason that some people have withdrawal sooner than others is not limited to dopamine release. It is a factor of how long methadone stays in the body, and that is extremely variable among populations of people. The half-life of methadone varies from 15-60 hours, up to 150 hours. The variable half-life easily explains this disparity among and between methadone users. Some of that is explained in this scientific article, Mathematical Model For Methadone Conversion Examined.

          2. Hi, I’m not good at this. I enjoyed your post and I’m very proud of you and your amazing life n self accomplishments WOW…. MY daughter has been on the methadone since 1998 and heroin year’s before that. We have lost our family to drugs. I take pain meds but I’m afraid of methadone because of all the death’s probably from the half lives and mixing other drugs..I would love to hear your story. God’s blessings to you and family.

          3. Thanks for your comment! I would love to discuss a few things with you. I will send an email soon. Blessings for all you are doing and many congratulations as well!

      3. I have been on methadone for chronic pain over 15 years and tapered from 120mg to 60mg over the past year with my doctors approval. My goal is to try to eliminate opiods if possible.
        Due to an arythymia my doctors PA titrated me off the 60mg methadone to 2-15mg morphine daily with 2-15mg immediate release for breakthrough pain. Im now on a pain rollercoaster with releif only if I take immediate release close together. The only other meds i take are thyroid, cortisone, welbutrin and baclofen.
        Im almost certain its methadone withdrawel or an incorrect morphine dose. Please explain how to apply the MED formula to be able to converse with the PA using data vs. my complaints.
        Is there a way to “flush” methadone out of my body or shorten the duration of these symptoms? Could another medicine be used to alleviate what feels like bone crushing pain until i adjust?
        Thank you kindly

        1. Dee, This is too complex to answer via this forum. You PA may contact me directly. The short answer without getting into opioid conversion specifics is that YES, there are drugs that can blunt or eliminate withdrawal symptoms. Examples include clonidine or Lucymera.

          1. Hey Jeffrey, just lying here sick as I ran out of my pain meds My Daughter has taken methadone daily for the last 20 year’s. I’m Leary of it.I know I’d saves lives and if not taken as directed can take one’s life too. Question. How much methadone would one start off with if they took 50 mg of oxycodone daily for many year’s? P

  31. i have to disagree about opioids causing tooth decay. I’ve been taking 60 mg of methadone and about 75 mg of oxycodone everyday for about 12 years now, plus 4 other drugs and lately my teeth have just started falling out. This past Friday, one of my front teeth just fell out of my mouth. My other teeth are literally crumbing to pieces. I did find scientific studies on the net that show that methadone as a direct cause of tooth decay, but very little on oxycodone. I have always been extremely dedicated to taking care of my teeth my entire life and literally day before yesterday one of my other front teeth just fell out of my mouth. I just about started to fricking cry. I’ve lost two others in the front and I have about 4 more in the front about to go, and i have 5 or 6 cavities on my bottom teeth. I met with my pain management doctor last Thursday and, of course he denied any severe adverse effect from the opioids as a cause of tooth decay with the exception of dry mouth. But even dry mouth is not normal, it is a direct result from having to ingest opioids. I’m only 58 and am facing probably 10 to 15 thousand in expenses to repair my teeth. I haven’t been able to work since being injured nearly 20 years ago, so I’m sure that gives away an indication of my financial situation. I definitely do not want to have to wear dentures at such a young age. Every single person I know who had to try them couldn’t wear them because of the pain from the inability of them to fit properly. This past Friday, my pm doctor called and sent me a small check to help me pay for my teeth problem as I guess in hindsight he may have felt a tiny twinge of guilt. That small check wouldn’t even cover fixing one tooth. I’m can’t read his mind as to what triggered that act of kindness, but I do appreciate it. He is actually an awesome doctor and I don’t really blame him but I just wish someone would have warned me about the increased susceptibility to tooth decay from ingesting these damn drugs. I need a miracle.

    1. I’ve never seen tooth decay from opiods, but there are several other drugs that are commonly taken by patients with chronic pain that are more likely to cause this problem. Gabapentin and pregabalin are examples. The other most common drugs that cause this are any drugs that have what is known as anticholinergic activity, all of which decrease saliva production. Saliva is a necessary because it kills bacteria and keeps the natural balance of bacteria in the mouth in check. These drugs are most of the antidepressants, but especially those in the class of tricyclic antidepressants – these are the older ones like amitriptyline. There are many other drugs that do this too. Some examples include hydroxazine, diphenhydramnine (Benadryl), orphenadrine, cyclobenzaprine (Flexaril), quetiapine (Seroquel) and many others.

        1. I am not sure but, I have the same problem.. I have been on methadone for 20 years & OxyContin. 100mg meth & 90mg oc. Since I have been released from the ARMY.. I have had teeth problems and feel like I am not getting enough. People tell me that it gets into your bones.. but I have not had that problem… I am 54 and have had more surgerys then I can count.

          1. I would like to get this information to my pain doctor. I have been talking almost daily Methadone for the past 30+ years and I have not had any success getting off it. But my doctor is beginning to do just that and abandon me. I like millions more am in much pain and don’t know what to do.

          2. You’re welcome to print out my replies and the article I sent in my last reply, and share them with your doctor.

      1. What are your qualifications that give you the educational or occupation based experience to offer your comments ?? I have CRPs I and II had been on opiates for 4 years when I began developing cavities at a rapid rate then in 2014 I lost 4 of my front teeth , they just loosened and 2 fell out with not a cavity on them. 2 more fell out after breaking above the root. I’m about to lose 4 more and soon I know I will be toothless. Insurance pays 50% for 1 set of dentures a year. However due to the CRPS that also my mouth and gums have so the pressure of dentures is extremely painful . I’m not able to chew with gums it hurts to much so starting in 2014 when I lost molars I had to change to a pureed diet. Don’t tell me these drugs aren’t linked to tooth loss until you have lived in my shoes. Try asking for a New York Cut Steak Med rare Baked Potato and asparagus pureed. The waitress will laugh at you and anyone close bu will stare.

        1. Your individual case may be true, but methadone has never been scientifically linked to bone or tooth decay. I’ve known people that have been on it for 15+ years with perfect teeth. More than likely you either didn’t brush your teeth enough, especially after eating sweets and sugar that methadone makes you crave.

        2. Russell: “WhAt ArE yOuR qUaL!f!cAtI0n$?”
          Everyone: “Well hes a physician & also not responsible for your poor personal hygiene? Take ownership & always remember, if you cant afford to hire a plumber & too unskilled to repair your own sink, the water department doesnt owe you an apology. Have some dignity about yourself, fool!.”

    2. I am a 46yr old recovering Heroin addict, and have been on Methadone for 21 yrs. I’m like you in the sense that I’ve always went to great lengths to take care of my teeth. I have always brushed 2x a day and flossed regularly. It has paid off, and I’ve had very healthy teeth, but the past yr or so my back molars have been getting bad. I don’t have any that are falling apart, but I do have some decay. I have chalked it up to getting older, which I think that is what takes place when you age, please don’t think I’m being sarcastic, because I’m not. I’ve never heard that opiates and tooth decay are related until this post. I do know that Methamphetamine is related to tooth decay, BAD! Anyway, I wish you the best of luck, and I’m sorry I couldn’t offer any encouraging thoughts! Good luck to you!

    3. TOTALLY AGREE WITH D.A. the tooth decay from.using opiates! OPIATES cause dry mouth which like u said is one of the # one things leading to tooth decay &/or tooth loss! I have the same problem as we speak I am 29 years old on methadone for 7 yrs

    4. Over 12 yrs and ur age I think u could Blane many other things, The way u describe one tooth just falling out and others about to do same, then you mention 6 cavities on bottom teeth..Unless this all happened in a day it seems like you maybe could have like millions of us got regular check ups, filings taking care of..I’m not saying I have the best teeth but I’ve never had 6 known cavity at once if so after 3rd I’d b at dentist.That’s why people’s teeth r lasting longer n longer. Yearly checkups.

    5. I myself have had a rapid tooth loss issue since switching to methadone for pain management 4 years ago. I came to the conclusion that methadone itself has no effect on the teeth; however, it does cause dry mouth which leads to rapid tooth decay.

    6. Ive been on 185mg of methadone for 6yrs now same with my husband and both are having serious teeth issues they are just crumbling like stated nvr had any dental issues and now its gotten horrible

    7. Do what I did. Get all of your teeth pulled out. When I did it, the option for implants were non existent, so I got False Teeth. I have a calcium deficiency, so no matter how good I took care of my teeth it did not matter. They would and were crumbling, falling / breaking off in chunks, etc. The expense to get them repaired was insane, so as they are going, I would have them pulled. I got so sick of the constant pain, not being able to eat, etc, that I found a surgeon who seen how bad my mouth was and knew it was inevitable anyway, so he agreed to pull the remaining 19/20 teeth. Let me tell you, it was the best decision I have ever made. I have had 0 regrets. Nobody can tell they are fake, they are perfect, easy to clean and I NEVER HAVE TO GO IN TO A DENTIST AGAIN (I hate dentists). Trust me, get them all yanked.

    8. Methadone gets in your bones whether you want to believe it or not and teeth are nothing but bones and the first thing it attacks is your bone marrow and your teeth enamel or tooth enamel

      1. That is incorrect. But, as with other opioids, it does decrease hormonal levels such as testosterone and estrogen. With diminished testosterone, it can lead to osteoporosis. Osteoporosis can certainly affect teeth.

        1. 15ml meth and otc tabs and codydramol and dihydrocodeine for ages now only on 50ml meth and sleepy how do i stop this sleepiness and memory loss at times?

      2. BN,, Don’t give up! I know it ‘s uncomfortable , but you can make it. I remember when I came down from 10 mg. from 60 to 30- to 20 and 17,5 all within 10 days. I said that was to fast and went to another Dr. who brought me down 2 1/2 mg a day every month. It made it more comfortable’ and now I am off 6 days The 5th evening I went in for help. I showed them a copy of Dr. Fudin They gave me Dicyclomine, It helps to reduce the symptoms of stomach and intestinal cramping. plus 3 days of muscle relaxers, and trazadone for sleep. I don’t believe, how much it helped I feel 70% better. I wish I had gone in the first day of withdrawals. My biggest problem was upset stomach and cramps. I lost 29 lbs, but the methadone had me eatting unhealthy foods sweets and crap.!! Ask your Dr. if he’s ok with Clonadine for cramping or something in the same family. Take a copy of Dr. Fudin’s feedback. . You’ll look back and realize, that all those years were mostly a blur. You’ll starting thinking again. You’ll make plans, to do those things you gave up on. Please fight it and don’t give up…I’m 100% behind you, as well as do many others, who want to be where you are. Prayers help.

    9. Methadone 100% makes your teeth fall out. It’s actually from the DRY MOUTH is causes. My mom has been on it for about 10 years, and her teeth must started crumbling and all falling apart. She had to have ALL of her teeth removed, and get dentures. So if someone says it doesn’t affect your teeth, they are lying!!!!

      1. Tracy, Methadone had no appreciable anticholinergic activity, which is what causes dry mouth. Common drugs that do that that activity are most antidepressants, certain antipsychotics (ie those used also sometimes for sleep, schizophrinenia, mood disorders), antihistamines, certain anticonvulsants (anti-seizure meds) and certain sleep agents. If your mom is on other medications in addition to methadone, it is more likely one or more of those.

        1. I, personally have been on Methadone for 12 years. Was on 90mg for the first 9 years but have now tapered down to 21mg. 12 years of Methadone everyday and never have I experienced any dental issues or dry mouth. I believe both issues are caused by sugary foods Methadone increases cravings for. If dry mouth is an issue, there are over the counter sprays and mouth washes that help significantly.

    10. FACTS! I had “perfect” teeth prior to methadone and after 5 years at a clinic my teeth are ruined. I don’t care what ANYONE says… I’ve witnessed multiple people complain about losing teeth after being on methadone for an extended period. I was always complimented on my teeth and now I am going through massive dental work month after month to restore my remaining teeth. (Back teeth are gone) The decay is similar to “meth mouth” Methadone seemed fabulous at first after being prescribed ridiculous amounts of fentanyl, dilaudid and oxycodone for years and suddenly realizing how absurd it was and what a serious predicament I was in. (My Pain Doctor is in prison in fact) The trust the doctor thing is highly overrated, especially when it comes to pain management! I actually resorted to a shorter acting “street equivalent” for a year to get off of the methadone before going into a detox. I nor anyone I know would have imagined my life taking such a course. Never was I warned about the serious nature of such medication but rather told I would need them for life! People also say you can’t die from opiate withdrawal! That’s amusing as well! The detox center (paid for high end facility) had to send me to the ER twice. Heart rate was 36 bpm with low BP as well. There are exceptions to the norm with everything! Without medical intervention I would have surely died! I thank everyone that’s commented and all the doctors information on this site. It’s some of the most credible information I have seen online thus far. Prayers for anyone going through the hell of withdrawal and may God be with you if you MUST take methadone. I wouldn’t wish it on anyone unless they TRULY needed it and had no intentions of stopping it. Many may in fact need it… I did NOT! I didn’t NEED anything so serious from beginning to end. I have three herniated discs, degenerative disc disease and fibromyalgia. I have some pain off of all medications but they were worse in many ways while on all the meds. Problem now is while being off of all of the medication I don’t think I will ever feel “normal” again. I have an ongoing inability to feel pleasure from anything at all! If one starts opiates they better do their research first and know the commitment it will take to ever discontinue them. Best of luck and prayers to all.

  32. Methadone does not cause tooth rotting. It causes dry mouth which can lead to teeth issues. Just drink water and avoid the sweets cravings and you wont lose teeth. 224mg a day user. Cinnamon pills also help with sweating.

    1. So sweating is normal? I am brand new. I had been on 16mg of Suboxone and asked to try Methadone. I started on 30mg yesterday and the only thing I noticed was the sweating. :/ And I’m already a sweat monster, lol. And I definitely didn’t feel well last night. I can’t increase till Monday and only by 10mg at a time. And the doc is hard to get in with. Blah blah blah, I know. I will look for cinnamon pills! Thank you. Let me know if you have any more tips!

      1. i have been on methadone for a number of years now, after taking oxy i done as a pain killer from
        the street after doctors would not help me in anyway. i was a drug dealer at the time and it’s easy to come by trades, trade dope for pills, make the $ and get my pain away. at one point i was taking probably 15-20 oxy 80’s a day… 270 lbs 6’… when i finally lost my significant other due to pull use i was forced to get clean to get her back. not the best thing to do is get clean for someone else, usually it never lasts when i do it for someone else. anyway… as i progressed through my methadone use i found that the 30 mg they started me on was not enough. being a user and wanting to get back into the “nod” state i kept telling my doctor i needed more and more and he continued to give me more and more. at one point i was on 300mg a day the highest dose in my clinic and my doctor was still asking if i wanted to go up. however once again the “nod” got me and i needed off. so having carries (take home bottles) one week i forgot them at home and was working out of town. the first 2 days i was a sweaty mess but it was bearable. the funny part was i got 0 withdrawals and this isn’t bullshit as i thought it was… so after the first two days i figured well fuck i don’t feel sick i don’t feel anything, just a bit sweaty i can deal with this… day 4 rolls around… nothing still, no constipation, no diarrhea, no vomiting, no cramping no nothing just my regular body pains. day 5 comes around same thing, day 6 same thing. day 7 same thing… i contacted my clinic and told them what was going on and how t happened. i returned my carries to the clinic for them to be disposed of properly…. last thing i need is a kid getting into it and dying or anyone for that matter anyways… when i went to my clinic they asked me some questions and what not and i was th sick at all just still sweaty…. they had me sign a waiver saying that i was taking myself off of a 300 mg dose and that it was potentially life threatening and they explained all the risks to me and that i still wanted to continue with dropping the program. (waiving them of all liabilitys if anything happened to me) i ended up going 5 months with 0 withdrawals, no diarrhea, no nothing. however as soon as winter came around i had to go back into the clinic and resign back up due to the immense pain i was having from the weather change. i am now currently at 70 mg a day and function worse then when i was on 300 so i’m not quite sure how but… yeah… in my experience it was a placebo effect. if you assume your sour, your gonna be sour. i chose not to allow the withdrawals through and it seemed to work. i really don’t know how or why , maybe i just got lucky i don’t know. but i regret going back on it after 5 months of sobriety however the methadone does not leave your system for about a year or so. so your always wanting it for that next year or so after… howeve ei plan to leave it alone after this winter and then be done by. next winter season so i no longer get the cold winter pains

        1. CJ, I’m sorry but I tend to think you got lucky, but only because of my recent experience. I am on 140 mg a day of methadone. I am on methadone for heroin addiction and have been in it for 3 years now. I recently discovered I have cancer and am going through chemotherapy. Anyways, I began to notice after my second chemo treatment that I felt like I was in heavy duty drug withdrawal. I looked up the symptoms I was having, like severe RLS, insomnia, shaking, diarrhea etc. none of those symptoms were listed as part of my chemo. So I started with every medication I was in looking for methadone interactions and sure enough I found one of the meds they were giving me, a steroid, was blocking the absorption of the methadone. So in conclusion I went into withdrawal blind. Thank t had nothing to do with my mindset. I do pray and hope your experience with getting off methadone goes as smoothly as it did last time I just don’t want others to think they are in WD because of a bad mindset. I had no mindset about it because I had no idea I would end up in WD! Thank you for your post however because it does give me and probably others hope about getting off of methadone!
          Peace ☮️ Annie

          1. I got diabetes and experienced withdrawal symptoms all of a sudden, i was doing an extremely slow taper for over 2 years, i was on 150 mg. I would go down 5 mg once a month at first, then i lowered it down to 2 then eventually 1 mg every month, sometimes i would take a break to let my body adjust to the taper. Well during a pause and i was down to 32 mg, i hadn’t went down since the month before and i started getting severe withdrawal symptoms, i had stomach pain, twitching legs, nausea,dizziness and lightheadedness upon standing,i felt i would pass out at any minute. anxiety really bad,i kept getting a rush i get with withdrawal, some people get it some don’t, i do often, every minute or two, Dr explained it as my liver looking for medication,it feels like an adrenaline rush kind of but way worse feeling. I got so sick i ended up getting severe pneumonia from it. I told the clinic that i kept getting withdrawal feelings so they started to increase my dose. i kept going up 5 mg at a time and eventually when i got up to 67 mgs they said there must be something causing my symptoms and i had been going to my primary dr and emergency rooms often trying to figure out what was wrong. The clinic nurse suggested going to my OBGYN to have my hormones tested. She is the one who found out i was diabetic with my sugars up in the 600 -700 range and i was at the level where people usually go into diabetic comas. So i started being treated for diabetes, and the pills weren’t helping so they started me on insulin.That is when i finally started feeling better. So withdrawal is not just in our heads. I feel some people are different and are lucky. But for the most of us, we do get withdrawal symptoms. @Anne Maynard So i also think that any illness or stress on the body can cause withdrawal symptoms. I get slight withdrawal symptoms during my menstrual cycle. So having Cancer and especially going through chemo can possibly cause withdrawal symptoms from the stress on your body. I wish you very much good luck with your treatments and hope for a full recovery!

          2. Hi I’m responding to your post because we have a lot in common – with the heroin, methadone, and cancer.. anyways I would like more info on what you said about the methadone being “blocked” by the steroids. I have never heard of that but am definitely interested in getting more info on that whole topic… Anyways if you or anyone else could give me info on heroin-methadone-cancer treatment, etc I would be grateful thx.

      2. Just hang in there your doctor will get you on the right dose. I’m on 114mg a day. Once you get on the right dose you will feel great, I tried Suboxone myself and definitely like the methadone better, I like it way better. I was going threw it myself when I first started but once I got to about 90mgs is when I was good. But ya just hang in there you’ll get there, good luck

      3. Hi I had a huge problem with sweating issue due to methadone once I hit my 120mg mark .. I ordered “Vitadone” IT IS AMAZING! My sweats are gone. Good Luck!

        1. Che, This is a very complex question to answer. Buprenorphine could be more effective, equally effective, or less effective, depending on a number of factors. But it is surely a safer option and I have had many patients do better on Belbuca compared to fentanyl or Norco. My advice is to work with your doctor and titration the Belbuca as directed.

      4. My first time and entire time on methadone 3yrs I sweat nonstop could have changed tee shirt 15x if possible no exaggeration ur at very low dose also so my opinion it got worse the higher I went. I also gained 25/30 lbs luckily I needed some weight .I’ve always been told and noticed ppl gaining weight when beginning methadone n staying on it for 3 4 months and it’s noticeable. I could be wrong maybe someone could help. IS IT TRUE WEIGHT GAIN when on methadone is WATER WEIGHT?. I’VE been off and on it for yrs the swearing stopped and weight fluctuates.

    2. No, methadone does not cause tooth rotting, but I lost all my teeth when I was on methadone! My dentist told me it was because I drank such huge quantities of water that I diluted my saliva thus harming my teeth. Apparently saliva has protective properties for your gums and teeth. I wish someone had told me! I would have drank water through a straw, bypassing my teeth (although I guess that wouldn’t do much for the dry mouth) Wahhhh!

    3. Dre, thank you for the tip on the cinnamon pills. You would think after 20+yrs that my body would be use to the methadone, and I wouldn’t have the intense sweating, but it’s not. That is one of my biggest complaints with being on the methadone maintenance program, and I hear it from other clients at the clinic as well. Do you know what the cinnamon does to stop the sweating, just curious? I’ve also never heard of a cinnamon pill, where would I find something like that? But Hey, I don’t care as long as it works! Thank you again:) Shellie

      1. Shellie, as a methadone user myself, i got vitadone from my clinic, or from the website vitadone. Com and it works AMAZINGLY….it controls the sweet cravings and helps u to not sweat as much plus it helps u to not be constipated… i think it would help u alot…the cinnamon pills didnt help me no where near as much as the vitadone did…good luck

        1. Thanks for the tip! I have heard that Vitadone works as well. I know that you can get them on Amazon but does anyone know where else you can get them?

  33. 20 surgeries on my feet now complete shoulder replacement is recommended at age 56. While I never had the high levels of oxycodone I can say I definitely have addiction issues. I am down to 10mg of Methodone daily and cannot jump off, it is extremely disparaging. I know even though the low dose is supposed to be manageable it has affected my quality of life so much I am starting to get scared. I have outstanding support of 37 years of marriage and great kids. However, they are getting fragile that I want off of the Methodone.

    I have gone from a very active focused person regardless of the pain to reaching a point I am not sure there is help. I have lost everything I ever worked for as in my families ability to trust in me providing for them. I have lost focus which is not me at all. I find excuse after excuse not to get my business tended to. We have sold off anything of value just to keep utilities on etc. I am not one to be helpless and I totally pivot to the Methodone as the problem. At first I think it took the edge off of thinking about higher stregnth pain meds, then giving how long it stays in your system jumping off is impossible. The detox people won’t take me as they say I am below the level of detoxing, could it just be my courage is gone due to the long-term use of this crap? I think it’s going on 8 years I have been at this dose. In one regard it seems frutual to keep trying to get off as all the doctors say don’t get off – it’s not enough to be a problem. Since everyone’s dynamic, there is no chance they know what it does to any one person. Any tips on jumping off?

    1. My world went up side down when I injured and fractured my spine and introduced to Norcos hydrocodone 10 mg I started taking 3 pills a day then I started taking 5 pill daily several months later it started getting out of hand to the point where I started taking 18 pills a day and when I ran out of pills I started feeling sick and going through withdraw and feeling miserable my doctor cut me off of norco’s so I had to use other sources to get them so I wouldn’t get sick my addiction got very expensive and out of control so then I started to get help and found a methadone clinic they started me out at 15 mg I am at 80 mg now going to the clinic everyday became a challenge a lot of times I feel hopeless of my situation I tried getting off of methadone I went from 80 mg to 6 mg I started having problems at night going to sleep my nerves on my legs we’re out of and having panic attacks and at times depressed I feel methadone has taken over my life… I think methadone can cause you to have psychological problems they increase my dosage to 12 mg I’m going to have to be very strong and very positive in order to Wing off methadone I heard methadone is synthetic heroin so I recommend to Wing off methadone completely

      1. Im 61 and been getting methadone off the street for a year. I was pn prescription opiates for almost 20 yrs for pain until this gpv. crack down i got pissed i thought they were taking me down to quickly so i took them often and was cut off anyway i found access to methadone after chasing heroin in the tenderloin of SF well the methadone ended and it been 7 very rough days my last dose was probably 15 – 20mg i didnt think it would be as bad as it can be flu symtoms is a crock i never had flu like this it!l make a grown man cry good luck

        1. How are you now, I know i prayed for death to take me for nearly 20 days, Don’t believe the bullshit 1 week my ass. Try to get into a clinic of some kind. hang in there 16 months later i was off that shit too and still clean to this day

      2. Just wanted to to know, I’m 7 days off of 35 mg of methadone after 14 years. Clonodine 0.2 mg WILL stop that withdrawl feeling you’re having at night. It’s not a narcotic and should be easy to get because its non narcotic but it DOES HELP. GOOD LUCK!

        1. I’m down to 24mg after 9 years of being on this crap. Going 1mg a week. Using kratom to help. I also have neurontin, weed, b12, and vitamin d. I was feeling shitty in the morning but now with all that stuff i really don’t feel too bad.

    2. I’ve tapered down from 149 to 26 mgs over the past 2 years. I taper in cooler months to avoid sweating profusely. I go to a methadone clinic & they give you daily doses of liquid methadone. It comes out of a machine into separate daily containers so it’s easier to control your dose & taper. I’ve heard the pills work longer but I’ve never had to worry about it. Liquid lasts for longer than 24 hours for me. Methadone clinics are a pain because they deal with street users so they will need you to go in daily & earn takehomes by staying away from illegal drugs. If you have a personal Dr prescribing it maybe ask about getting off the way I described. Maybe the pharmacy will have liquid & be able to dispense it in desperate daily doses in small containers. This is the best way. Marijuana helps too.
      Good luck

      1. I go to a methadone clinic as well i feel if u can smoke pot ull b able to come off my problem is i have a bone disease an i also have hemochromatosis witch causes me to hurt so bad to an then my back got broken an i have to go through major sugery soon methadone saves me from the OTHER drugs i was on cause i was buying more cause what i was prescribed wasn’t helping an methadone helps i would love to stop everything but im in pain everyday wish i had a pain dr who prescribed it instead of the clinic cause they screw u over but anyways i agree smoke pot if u can an colder months is better too good luck everyone

        1. The problem with that is a lot of methadone clinics ( at least he ones that are in states where marijuana is illegal ) don’t allow you to use marijuana. Oh how I wish. Lol. I would love to be able to smoke but my clinic does not allow it.

        1. Sure you can 12 years in one best clinics in my state and now its not legal where i live uet but ive been to several for courtesy doses on vacation and not one clinoc ive seen cares about pot anymore.and thats a fact

          1. Yes you can if you have a medical card. At least you can in my state! It’s also legal in my state, recreational marijuana that is.

    3. Dear BN,

      I can relate to everything u have said about methadone use and then some! I have been on it for about 7 yrs now. At one point I was up to 95mgs. I’ve lost my families faith, my job, my.friends, my TEETH, gain 80 lbs and worst of all I’ve lost the self respect and the ability to provide for my children that I once prided myself on. Methadone “treatment” has been the worst choice I have made throughout my entire life. I truly don’t even recognize myself anymore!

      So, I’ve decided to do something about it. I have weened my way down to 15mg, and as of last Wednesday I have not taken a single drink. It is a poison that mutilate ur MIND, BODY, SELF WORTH, SELF RESPECT, AND SELF PRIDE!! My life has been torn apart by this DRUG. Everything was great while on the painkillers. I was doing to many, but I still got up early and worked my ass off everyday. One of the worst side effects for me is the depression it causes (that and the weight gain).

      Anyway, back to what I was saying. I have been slowly decreasing my dose for the last 2 yrs. And each and every time I drop my ‘doctor” work extra hard to bring me down, and convince me it was a bad idea. It’s now been 4 days with no drink, and i do feel a little rough around the edges, but it is bearable. The hardest part is getting next to NO.sleep. all these effects WILL.go away if I stay away from the drug. If I continue using g it I will never be the vivacious, hard working, fantastic Mom and friend I know I can be, the woman that is teed inside me drowning on poison

      You want advice on how to quit…..pick a day and just…..QUIT☺ I am not trying to tell u it will be easy, because it won’t be. But what in life worth doing ever really is.

      Well, that’s my story. I hope it helped you, aND gave you the curate to fight this demon. One last thing, you WILL need ur family’s help. This is not something you can do on ur own.

      1. This may not be the right forum so I apologize in advance but I trying to find some sound advice for switching from Suboxone 8/2 mg 3X day TO methadone 10mg 4X per day. I have been on that script for 3 yrs after getting off of prescribed 450+mg oxicodone/oxicotin, soma and zanax for chronic pain. After 15 yrs of pain pills due to numerous vaginal surgeries and digenative disc disease I became highly addicted. I have zero experience or knowledge of methadone but due to increased pain from yet another medical problem my addiction specialist Dr told me to try methadone for 1 week and come back to see him. I’m starting this over holiday weekend and am very scared. Everything I’m reading scares me! I’m married 15 yrs have a 13 yr old son and I can’t afford to go backwards. Please help…thank you

        1. I have severe pain that keeps me from being able to clean my house sit upright stand walk out to my car shop for groceries it affects everything that I do. The only medication that has ever manage to do anything for my pain has been methadone. Unfortunately because of the opiate crisis saying they’ve closed down just about every pain specialist within a hundred miles so now everybody who was seeing doctors is now going to the clinic and instead of paying $5,200 for medication we’re paying 400 to 500 dollars. People have a lot of different experiences with methadone but two 10mg methadone one in the morning and one at night take better care of my pain than 80 mg oxycontin 3 times a day. But again everyone is different so you can’t look at what happened for me and think that’s going to happen for you just like you can’t look at what happened to the other people and think that you’re going to have that same bad response.

        2. Methadone changed my life I was on so many prescriptions I lost count and still had severe pain and migraines everyday I couldn’t do anything without my meds after getting on methadone I’m off all other prescriptions and pain free I went from going to the Dr once a week to not going to a Dr except for a checkup! If you follow your Drs advice and have the right dose it’s the best pain medicine you can get!

    4. You can do it! Just kick it with the support system. I’d give anything to have that. You may be pretty sick for a few weeks but it gets better. I cold turkeyed 400 mgs and was sick for a month physically and relapsed 5 months later due to hot and cold sweats. Yes, even 5 months later. My dose was too high. I promise you it won’t be that bad. Do it while you can.

    5. I would stop if I could get that low – you will have minor discomfort for a couple of days … Just do it! I know ppl on 185 and higher who have been admin detoxed at a facility before – they take you from 185 to 0 in 14 days – talking about crazy. I’m on 70, used to be on 120 but decided I just needed enough to help with pain so I got down to 70. I would love to get off but I have the pain issues and love all the other opiates way too much. 10mg though … wouldn’t do anything for me and would be a waste to take at all.

  34. To anyone thinking about ending it because of pain please read this. I have been close to 3 people who committed suicide including a best friend (I dont and never had made best friends easy and I miss him to this day 25 years later), a cousin who I loved like an older brother and my girlfriends brother. 1 did it because he has diabetes back when it wasn’t as treatable if you had it as a kid, my cousin over money and my girlfriends brother over heroin addiction. I also just recently got to clean up the aftermath of my father’s friend killing herself due to pain she couldn’t get treated.

    Now a little about my story, in 2006 I drove a snowmobile into a tree at nearly 100 mph how I didn’t die was a miracle or bad luck depending upon how I look at it. I say bad luck because I broke nearly every bone in my body including both my neck and back in 2 spots. I didn’t bleed to death because I was drunk and it was cold. Somehow I didn’t get paralyzed, but since then I have lived in remarkable amounts of pain. When I finally broke down and went to a dr for pain management he said he couldn’t believe I was walking around and functioning for the 4 years after recovering from my accident which took almost a year. I first went to this Dr in 2011, over the following 7 years I ended up on a combined daily dose of 1100 mg of oxycodone and oxycontin. 10 80 mg oxycontin pills and 10 30 mg oxycodone pills daily. In some ways my life was better in others it wasn’t. But my pain had been greatly reduced.

    Early this year my Dr lost his medical license due to the narcotic nazi’s aka the DEA. So I was taken off at least a three year 1100 mg dosage overnight basically. No Dr would take me because of my old Dr and script level, which seems like discrimination but what do I know. What I do know is I went through hell, I bit the bullet and went to a rehab place to get on suboxone even though it was humiliating. My pain was through the roof even with the help with suboxone. I’m now off of suboxone and live in constant extreme pain. But I wont end my life or even consider it.

    I’m not in love with myself, nor do I fear death. The reason I won’t do it is because I have experienced and witnessed first hand all the torment it puts anyone who cares about you through. If you love just one person in your life believe me the mental pain you will put them through by suiciding is at least a thousand times worse then any physical pain you are in.

    If you don’t believe me or think your pain is greater then anything I’ve been through there is a good chance you’re wrong. But either way I do know the pain caused by suicide and you don’t want to do that to anyone who cares about you.

    1. Wow is all I can say , thanks for sharing your story I don’t think it’s fair people like us who were put on meds to help our pain have to suffer because others mis use the mess when we are clearly in need of it I myself was in a accident and broke 62 bones and like you no one knows how I walk around everyday , work , take care of a house and kid by myself as of now I was reduced to 6 10 mg of hydrocodone a day which is better than nothing but still a struggle but they are trying to take that away too I would never take my own life but have no clue what to do to get by daily

    2. Look up Gabapentin. Trust me on this dude. This is a drug for nerve pain but for people who like me just had to get off opiates and couldnt find anything else I finally was able to get on this for Methadone withdrawls and it really is better than nothing. What do you have to lose? Just trust me and ask your dr about it and try looking it up for yourself!

      1. Yea but thier trying to say that those are also being abused now .. and i tried to get on them and was DENIED .. my therapist laughed at me because she prescribes me adderall and said thier was no way she could prescribe me two narcotics .. but the point is they are finding thier place unfortunatly it feels to me like ( a black list ) because of the BAD GUYS out thier that the other poster was reffering to who are being effected by the addicts .. on the same token the addicts are also being denied an option that isnt methadone lol or subozen .. but maby thiers something to that ?? Ive read that neurontins if ur trying to get off one med ( enough to really help u ween ) are also addictive so what to do ?? I think maby it all comes down to being READY period…

        1. Hi
          I live in Ottawa On. My dr is trying to get me off of 60 mg Oxy cod one a day. We’re having opioid crisis from addicts overdosing. He’s not trying to replace it either. I’ve never gabapentin being used for withdrawal etc. I didn’t know it was a narcotic. Would you be able to tell me more?
          Thank you

        2. I have to wonder about your dr. As gabapentin is NOT a narcotic. Its barely even controlled. Please don’t think i am attacking you i am just sick to death of people who don’t understand what pain truly is telling those of us we aren’t that bad. How busted up do i need to be for a doc to say , i bet that hurts and mean it?
          Ive been on a taper off methadone for about 3 months. From 90mg a day to 10mg a day. And let me tell you if feel like crap. I recieved my injur while in the service back in the early days of payback for 9-11. And at first was lost, after pretty much everything on the counter was tried, i hate taking pills. Then along comes a doc with a wonder drug, you guessed it methadone. And YES it did better my daily life. Got me off my ass and working again. Even helped with migraines from Post Traumatic Brain Injury. There are a few things I would have loved to know up front… maybe a little note that said” oh ny the way you’re teeth will rot out, and god forbid we try to take you off them.”
          But truthfully I would have still taken them because what i was headed for was a more perminent pain reliever.
          Anyway i am rambling, but my fellow earthlings, hopefully we all still are, I truly feel your pain. But i have to agree with the above comments this pain we all have in one form or another is NOTHING compared to what we deal to our loved ones when we punch our own ticket. Stay strong help is out here but you have to step up and ask.
          Love to all
          ( I Don’t Kneel) sry thats going to the gestapo who no doubt monitor all.

          1. Yes gabapentin is the generic name for neurontin. Also what some people don’t realize is that first
            Gabapentin is not a controlled substance yet. They are pushing for it though. Also just because something is a controlled substance it does not make it a narcotic. A narcotic is a class of drugs while a controlled substance is just that. A controlled substance.

          2. For clarification, a controlled substance is a prescription medication given categories II-V by the DEA, based on abuse potential. II has the highest abuse potential, and V has the lowest. Schedule I includes drugs that are not approved for medicinal use in this country and which have the highest abuse potential.

        3. Thanks for the tip! I have heard that Vitadone works as well. I know that you can get them on Amazon but does anyone know where else you can get them?

        4. Sorry but adderral is not a narcotic and gabapentin is an anti convulsant so I don’t know what your therapist is talking about. I am on a very high dose of gabapentin and unfortunately it does nothing for my nerve pain. It helped for maybe the first six months but coming off is no joke. Make sure you know this before going on— coming off has some withdrawals that aren’t too pretty.

          1. Most likely, her therapist is using the word “narcotic” to mean it is covered by the narcotic (controlled substance) laws. this is often misquoted, and you are correct Laura; it is one of the reasons that we refer to those drugs as “opioids”, not narcotics, because the latter has become a derogatory term and is often misused.

        5. If it’s not with pain involved, clonadine for withdrawal symptoms. You can go into the ER and say that you are getting off narcotics and was told on this site that clonadine (ask for it specifically) works well for withdrawal symptoms.
          I am a chronic pain patient, after being run over by a drunk driver, and years ago was abruptly cut off my medication. I was lucky enough to be at Johns Hopkins, and they gave me clonadine for the withdrawal and a referral to their pain clinic. Trust me and the doctor, clonadine and my bathtub worked wonders. This was in the 90’s and I cannot believe that in all of these years–especially with the Internet, addicts, websites, forums, and seemingly medical providers–clonadine is not widely known about and used. Perhaps, if it were, so many people would not have been hitting the street and this opioid crisis might not be what it is– including making life very difficult for legitimit pain patients, like myself.

      2. Antidepressant are being proven to not work and cause even worse withdrawal I know because I was on them all and it is hell. Opiates work for me and nothing else. I was only on 65mg a day and they have forced me to 40?mg a day and it’s a living hell. I have a job and two young daughters my wife is exhausted trying to pick up the slack of what Ivan and can’t do. The DEA is a bunch of puppets for the drug industry period. Try medical marijuana or cbd. Try Kratom too

          1. Dr Fudin, I had been on 60 mg of oxycodone, and 30mg of morphine for 12 yrs. Same group, but new doctor took over for my doctor who relocated, and changed me to 10mg of methadone 2 times a day,and 2 -10mg of hydrocodone. 1 yr later,Now there’s a new doctor, who said he doesn’t like methadone, and would have never prescribed it,and wants me off of it. I’m still in a great deal of pain,but I deal with it doing chiropractor,deep tissue massage,and physical therapy every week. I really never knew what methadone was,because i had never been prescribed it. Everything I read though, and hear,methadone is a terrible medicine. What medication could take place of 20mg of methadone everyday? Or should I stay on it? I appreciate your help Dr Fudin. Thank you

            Good luck everyone. I think talking to someone that knows what we’re going through helps,like this discussion group.

          2. Kelly,
            Methadone has many attributes that other opioids don’t have, but it also has pitfalls, especially with regard to drug interactions and other risks. It’s hard for me to answer your question without knowing your entire medical history. And even then I couldn’t give that dirt if advicd here.

      3. I almost died from Gabbys only take advice from a doctor I had seizures vomiting etc almost died(I was prescribed for nerve pain)..only take what is prescribed by your doctor and monitored!!!!

          1. Ms. Correct,
            I have to laugh at all the comments off self-serving in their own right Pain patients. That addicts ruined it for you guys. Wake up! Most ADDICTS started with pain and doctors, and like a lot of you couldn’t get them anymore, I don’t care WHO you are, if you were on Opioids for any length, then you are Opiate Tolerant(an addict), as you keep saying. LOL…… When you’re scared and getting cut off or switched down , WDS is the first thing you want to shake off, it’s only normal. So hypocrites try again…..

    3. Yea thanks for sharing your story. Im on 70 mg of methadone and it works pretty good. Not nearly as good as that awesome1100 mg oxy script. Suicide is all bad for sure. Rip to your friends and Anthony Bourdain and anybody who has ever been effected by suicide or addiction and homicide. Be safe !

      1. Just to add a little something 2 previous post. .RIP 2 ur friends…Please be safe & take a second 2 think as bad as it gets or is ,,sun will come up tomorrow…suicide should never be a option. Life is beautiful.and if ur down or ur bottom. . well then there’s no place left to go but up.I struggle every day with addiction 4the past 20yrs.. but I try to fight as much as possible. ..

    4. Dave that was a remarkable heart felt reading. i too was in a terrible crash only on a motorcycle and broke 9 ribs, shoulder ,clavicle ,wrist.closed head , spine fx,trauma,collapsed lung and oh yeah a comma x 2 weeks. i am now after 15 years of oxie levels near yous then switched to 800 milligrams of morphine for the last 5 years along with 9 dilaudid #8 per day. now that we have the opiod crisis they have lowered me to 200 mg and getting lower each month. my first dr, retired sorta , he kicked all high dose pt. to curb.dr. number two continued my care but got arrested trading scripts for sex. dr number 3 , my family physician kept me going for another year until the practice stop writing for chronic pain opioids.with luck dr. number 4 took me in at a pain clinic was very sympathetic but said he legally had to lower doses. i did not notice the initial dose lowering s as bad until down to 400 mg now i have been up all night in serous pain and really feel like i am detoxing bad, I had a coworker whose husband killed himself due to pain that the insurance co. would not treat except with an internal electric stim on spine, he shot himself a week after it was installed. my coworker was crushed ,but said he was in so much pain she knew something would happen, pain really sucks writing this awaiting my dr office to open, hoping he may help i have never asked before . people do not deserve to live like this but as long as politicians are willing to trade our pain for votes were doomed. peace out

      1. Hi there Thomas! I am curious about the doctor you mentioned that got arrested for trading scripts for sex, because funny enough mine did too. I am curious if you live in the same state as I do (Indiana), and if we had the same doctor…? How crazy would that be? But when you mentioned that I thought “How many pain docs are out there that have done that?”. I finally found a great pain doc, although that’s not what he goes by. He is listed as a Opioid Management Doctor, and their office is listed as “Opioid Management”. Thet do things differently that a typical pain clinic, and they dont treat any of their patients like addicts.

    5. I go to a pain management clinic and have been there for years at the same 60 mg of methadone for my severe pain. I have never asked for an increase with my pain medication. I also take gabapentin and cyclobenzaprine PRN. I went to my usual monthly doctor appointment and out of the blue he said he is taking me off of the methadone and switching me to oxycodone. I told him I would rather not make changes but I did not have a choice and he took me down 10 mg per month from the methadone while switching me to oxycodone 30 mg. I am up to 4, 30 mg tablets per day and he said that is where I am going to stay with now zero methadone I have never been going through more extreme pain in my life. This doctor who is really a physician assistant seems to have problems when he’s trying to do this equation trying to give me enough Oxycodone to the equivalent of the methadone I was taking but I can honestly say there’s not a snowball’s chance he is even close because I have never had pain like this in my life. I have been to the ER twice because of the pain severity and as anybody knows who is on pain medicine you cannot get any help when you are already being prescribed by another physician. My question is does anybody know what the equivalent is of 30 mg of Oxycodone to 60 mg of methadone? By the way when I asked the doctor what is the reason for all of this change? Each time I went in there and he told me something different and never gave me an honest answer.

      1. Dawn you may be better off to go to a Methadone clinic. Go there and say you are addicted to opioid’s, even if you aren’t. They will put you on the methadone you need. If what they give you is not enough you just tell the methadone clinics Dr. you are still having bad cravings and withdrawal and they will up it. I started at 30mg when I went there for abusing Ultram, and I am now on 95mg of Methadone. Ultram isn’t supposed to be addictive but the Dr. had me on such a high dose I had terrible withdrawal, I couldn’t get off the shit. The I got pregnant and knew I had to get off of it. I tried all the rehabs first so they could taper me off the Ultram but none would take me b/c I was pregnant. The only one that would take me was Methadone clinic. They said if I just went cold turkey off the Ultram I could miscarry and they told me the methadone was proven safe for pregnancy. I am an addict, I crave that feeing of contentment you get when you are on pain meds. However I will never go over the 95, I am in the process of cutting the methadone down using Gabapentin , but now they are starting to say Gabapentin can be addictive, I swear you can’t win.
        But anyone in enough pain you will have more luck going to a methadone clinic then a regular family dr. they are so scared of the DEA.

        1. Wendy,
          I would NEVER refer anyone to a methadone clinic. As you, an addict , are well aware, Methadone is one of the worse meds to get off. I would suggest Dawn stick out the meds they are putting her on until she is able to start dosing down regardless of how long it takes.

          1. If you really want off Methadone, Why not ask your doctor to switch to oxycodone Instant release formula , And then slowly wean down by no more than 5 Mg per week or less even dropping 10-mg per Month. If you have the will power to step down slowly

          2. Actually, Wendy was just trying to be helpful. If you read Dawn’s post you will see they changed her from methadone against her will and didn’t tell her why. Dawn isn’t necessarily trying to get off the opiates because now that they changed her meds she is in more pain than ever which is why she has been going to the ER. She’s using the methadone for pain not addiction and methadone tends for many people to be a much better pain reliever than oxycodone, which is why Dawn is experiencing much more pain. So it’s not about getting off the opiates but about finding something that will work for her. The methadone WAS working but now they changed it. So if they are unwilling to put her back on it she should either try to find another doctor or yes, actually go to a clinic. I know clinics stink but if it’s about having a life, I would rather be on a narcotic and experience some pleasure rather than be completely off and have no life due to horrible, intense pain. Trust me I know all about debilitating pain that makes you completely unable to experience any semblance of joy. And going to the ER generally does not help at all.

      2. Every where I go’ I feel they think I’m a drug addict…40 mg methadone 3 times a day for 16 years’ then Jan 2016 doc said I have to take away your zanex and start lowering your methadone to some new standard. well got me down to 20 mg 3 times a day and I started having trouble, couldn’t do much around my home and yard // complained about it. then received a letter from doc saying I failed a drug screen for pot and he would not give me anymore pain meds’ I said no way take a hair sample. but he would not even reply to me… This last year has been hell and so much pain and street drugs’ now I found a doctor but he insisted on a back stimulater. which was a week of hell’ then the 1st of Aug they took my now down too 10 mg methadone 3 x a day too 3 1o mg percocet a day… I called Friday and told them it wasen’t even close I’m taking a 10 perc every 4 hours just not to think about killing my self’ I’m 57 and have been here long enough’ it’s just not worth the fight anymore’ I’m going in Monday to see what they will do’ hanging in there but don’t really care anymore’ sorry for rambling if anyone see’s this //

        1. Please hang in there. I know it’s a hard fight but you and your life are worth the fight. Try looking up new pain management clinics or services if there’s a methadone clinic near you. Please don’t give up. You’re a strong woman. You’ve made it this far for a reason. The storm clouds will pass and the light will shine through.

      3. Wow that’s terrible. My doctor told me methadone is approximately 4 times stronger than morphine. So if you were taking 60mg of methadone then that’s approximately 240 mg of morphine or slightly more. This conversion barely worked for me. I’m on 30mg of methadone from a pain doctor and he briefly switched me to morphine and gave me 120 mg(60mg twice a day) and it just barely help me. I did have withdrawals and could have probably used another 20mg to keep all the withdrawals away. I read that 100mg of morphine is equal to 65mg of oxycodone. So if you were taking approx 240mg of morphine, that’s around 160mg of oxycodone (maybe a little less due to the conversion) but I bet you would actually need more than that. Methadone is a much stronger drug than oxycodone. My doctor offered to switch me to oxycodone— that was when he also offers the morphine— I said hell no to the icy and changed to the morphine because I knew the oxycodone would not hold me and the pain would break through like never before. I believe the pain relieving properties of methadone are much stronger than than oxycodone. You should try to find out why the switched your because that’s just wrong. Did you have a problem with an EKG or something?

    6. I have not been quite suicidal due to my pain but there has been times where I think it was close. I feel for you.

    7. Dave, Thank you so much for your story. It came at an appropriate time. I am at wit’s end with pain and the psychological traumas I’ve had over recent years would be enough for most people to have ended it. I don’t have any close friends, though I have two family members and my faith. God has always helped me at these times and I feel he is waiting to help me now. May God bless you too. Oh, the one suggestion I give everyone is to have a whole arsenal of options to help with pain. It will help.

    8. Thank you for your input. I have been suffering severe pain that is unbearable & with the supposedly opiod crisis. My treatment is so low I am always in unbearable pain. I as well am not aftaid nor fear death & the only eeaaon so far dor not biting a bullet is the repercussions to the living. I have several severe herniated vertebrae that constantly pinch the nerves, discogenic disc disease, OA & RA, retrolethesis of all lumbar vertebrae on & on. I really think with Baby Boomers becoming older & influxing the medical insurance agencies, social security, medicare, etc is the only reason for the supposed opiod crisis. As tylenol 3 was never considered an out od context opiod. It has been used to teeat arthritis pain, lower back pain & because the government & state want to save $’s whether than compassionately treat the aging populace. Shame

    9. My mom and best friend committed suicide and it sucks. My son has been trying for years now with heavy use or misuse of many drugs.

      With that being said…. I do get tired of the pain. I have Lupus and just get tired of being tired and sick…. and pain left from spine surgeries….

      What throws me over the top though is when our stupid government comes up with new changes that hurt so many innocent people.

      I have been on 20mgs of percocet for 5 1/2 years. I have never abused it or taken more. Now because people have abused it and been over prescribed…. even those of us who have fought so hard to stay at the lowest dose possible are being told No… it is not good for you… it is deadly…. it is seriously addicting.

      Seriously has anyone ever died on 20 mgs of Percocet? Now they want to start me on something called butran patches…. No thank you! long lasting… great so when you decide to take that away I get really long withdrawals.

      I am 56 and feel like sticking my head threw the wall…. it wont kill me but might knock me out few hours.

      I admire your strength to hang in there and deal with your pain. I cant believe you were on so much medication. It is horrible that other doctors will not see you because of what your last doctor did. That would be your fault how?

      I use to trust doctors and now I do not trust them or our government at all.

    10. I’m kinda in the samefix . I was on 190mg . Of methadone and got down to 70mg. I moved to Florida and boom they don’t give anything without pulling teeth. I had to get all new x rays and cats , get on a pain clinic and they cut me 10 mg. A month. They tell me that the law says only 35 mg daily but I get 40mg. Now they cut me by half , 20mg. A day and 20mg. Of oxycodone. The only thing that it does is bring back my spine pa I suffer

      1. I thought you can’t feel the oxycodone if your on methadone? I just started methadone I’m on 35 mg once a day and just curious…still trying to get whole facts about methadone

        1. Oxycodone is a full agonist opioid and so is methadone. Taking them together increases the opioid effect and could be dangerous and lead to overdose if not taken as intended or prescribed.

          1. Hello Dr. I am another who has taken methadone for pain. I have stayed on the same dose (70mg) a day for 9 years, unfortunately my doctor (who was an amazing man) just passed away and now I am having unbelievable problems finding a doctor to “take me”. Finally I had to go to the E.R. where I had an incredible doctor who just looked up in some pharmacy database where it shows I have been taking the same dose, same doc etc, he said “do not stop cold turkey, you may die”, and gave me 10 days worth. I am now on my 9th day, still haven’t found a new doctor and I am crying because my next option is to have to drive 2 hours to the nearest methadone clinic where I have to say I’m an addict when I am not, just to keep from possibly dying. Also I have brought myself down to 30mg during this ordeal. My pain is worse, but I am still alive. I have children, grandchildren, a job, a house, animals all that need me. I wish the CDC had statistics on how many deaths are being caused by their recommendations! What is the real reason this is going on? Someone told me hospitals have been having shortages in injectable pain meds more than they’ve ever seen?! I feel for all of you with similar stories. My life was good for awhile so I’m at least happy about that, I just hope the pain never gets the best of me now. But sometimes you think death would end the misery. I hate politicians who think they know better than doctors and patients on how our healthcare should be managed! Evil evil people!

          2. I am on 150 mg of oxycodone a day and my doc wants to switch me to methadone for the reason ” I’m trying to look out for you it’s cheaper, as I am self pay but tomorrow he wants to give me 120 mg of oxycodone a day and I think ,5 mg of methadone a day. Is this a problem?

          3. Teresa, Without knowing your entire medical history or seeing you as a patient, I cannot comment on dosing. It sounds like your doctor has a plan. If methadone is an appropriate option, it generally be introduced at low doses very slowly.

    11. Thank you for your response. I can’t believe you are alive! I wasn’t in a severe accident like you but almost four years ago I came off Prozac and for some reason it had a profound reaction on my body. 8 weeks later I started to experience bad pain on my face…at first in just small areas. Then after three months it was my entire face, eye lids, eye balls, lips and gums. They burn and sting constantly I mean all damn day. I couldn’t talk, eat laugh or cry. I had to stop working and move back in with family. They had to blend my food in the blender to sip through the straw. I baffled doctors… they all agreed it was a severe form of nerve pain like trigeminal neuralgia. Trigeminal is a horrible facial pain condition with one of the highest rates of suicide but it generally only affects one area of the face. My condition didn’t make sense because it affects my entire face and my eye balls constantly burn to the point where my vision is blurry and keeping my eyes open just hurts to the core. It’s like I want to take a knife and stab them.
      I understand about your doctor losing his license— he could have killed you and was way over prescribing. A similar thing happened to my best friend— her doc was giving her 250mg of methadone, 10mg of Xanax and 180 mg of morphine. I used to tell her constantly that she was way over medicated but she wouldn’t listen. Finally the DEA stepped in and she was cut off. So she went to a clinic. However a new doctor should have worked with you given your condition and what your poor body had been through. You were clearly in a lot of pain. It’s good your off I guess but your pain must be so bad. In my state the laws have been totally changed as to the dosages you can now receive. I go to a pain clinic and my doc gives me methadone but 30mg is the MAX. Other stares will soon follow as 90mg of morphine is the max and it’s equivalents to other opioids like Vicodin etc. it’s going to sweep the country but it’s taking some states longer. The methadone helps me so much but I desperately wish I could get a slightly higher dose to be more functional. Before the methadone I couldn’t do anything and was bedridden for 7 months as I tried all these other meds that did not work (non narcotics). I mean I tried everything. It was only after trying everything that I was offered the methadone and I jumped at it because as I said I had no life. At least now I can get out of bed and shower and do small things in my home but I don’t go out much and during the winter I can’t go out at all because the pain is so bad. If I have to go out for an appointment I have to wear a mask. But I could relate so much to your post because I constantly think about taking my life because the pain is so much to bear. I feel like I have no life and as though my life is meaningless because I don’t do much. I can’t work and I barely socialize. Are you very functional? I just wish I could so more. Sorry if there are spelling mistakes it’s my darn phone. Thanks.

  35. I’m having similar thoughts as Danny and I’m sure many others are abt ending things BC of my pain. And the fact is so many of us are treated terribly. Its a tremendously harrowing experience to be cut off of your medications. My current pain Dr. is prescribing 2 5 mg hydrocodone/day when I’ve been on a dose of 180 mg morphine. He took over for a doc who left. Now BC by the time I got in to see him my morphine was no longer in my system he refuses to prescribe it. I am now spending all my money buying morphine on the street. I’m having to panhandle just to keep out of pain. I don’t know what to do or where to turn. I can’t seem to find a Dr. who is willing to treat my very real pain. I’m on disability, fixed income. Even if I have to pay cash to a pain Dr. would be fine. But to pay one and get nothing is breaking me. He doesn’t care at all. I just don’t know where to turn. That’s why I was looking into methadone clinics. BC maybe it would help my pain. I hate the idea of having to lie to get pain relief and really I don’t want to go on methadone and have to go in every day. I’m not an addict. I’m in pain and I need medication. Why can’t we get what we need? Why are good people made to feel so horrible and worthless. It’s too hard and I don’t see an end. I’m in the bay area. My email is if anyone had any ideas. So sorry for any of you out there who may be experiencing this much pain and discrimination and hopelessness.

    1. I take 160 mgs of methadone daily, and it’s a nightmare!! I Doctors, Pharmacy s , people who DONT have pain,I feel ya, and I understand. I live in North Michigan, I drive 3 HOURS TO APPT EACH AND EVERY MONTH! I’m ready to take my own life, because this isn’t life 3 surgery s 6 discs removed, I have severe dergenative bone disease.Everybody thinks your just a dope fine Good luck

      1. Dean. Dean, hi. Please. I know I dobt know your individual pain. I can say that I’m very much able to relate as far as our “alike” surgeries and life long injuries, DJD/DSD/DBD. I was taking 180mgs avinza (time released morph caps) and then 15mg perc 3x’s p day for breakthrough pain. Id been on the same exact dose of morph for 12+ yrs.. It, naturally was not working so well, fair to poor. Backing up, I was taken off the breakthrough meds when i went to new pain management dr bc his P.A was playing God and literally throwing records away. That being said, mine were never seen and the dr discontinued them. 2 yrs later this pain dr couldn’t keep his hands and mouth to himself. Bye bye now you dirty rat bas….. Sorry. So here we go to a female pain dr.. Each visit the assistant asks, is your pain medicine working good fair poor…. I Kept replying, “poor to fair”. I asked dr her thoughts on a “medication vacation” . She agreed, we transitioned in 2 months, tapering the morph and introducing meth. You know this Chinese ancient dr refuses to manage/control my pain properly, as she said we would increase to 1-2 addtl doses per day. Providing me with 30-40mgs p day. Well she had a bit of a, shall we say a Freudian slip! Yup! First she plays on people’s pain and emotions. Says (although shes had no injuries or such) “oh my neck far wurse din yours and i no take no (deep long voice) pill. You disabled and no work on Medicaid you not take medicine only when you want bc people sell…… I kid you not! Shes also refused to continue my muscle relaxers for continued treatment of the aboved mentioned, fibromyalgia and another muscle disease. I was involved in a single car MVA and went misdiagnosed with a broken neck for 20 yrs.. By now…oh gaed! The damage is irreversible and so severe its left me unable to use my upper body. So spine specialist, surgeons and all the other this n that specialist, failed procedures injections and crap, 25 yrs later we FINALLY found a regiment that controlled my pain enough that it increased my quality of life by 60% and then you have my pervert and this off the hook & crazy pain dr thats playing on people’s pain and livelihood. So dont give up! Youve come waaasy to far. So…please help me to understand your input here. Were you previously on different pain meds and they converted you or youve been prescribed the meth all along? That seems like a truly high friggin dose. I dont know you and im concerned to hear you say you’re taming such a high dose. So if its creating this crappy quality of life please express to them that you need to transition to something thats going to better manage your pain. And explain to the dr how it makes you feel. I hear the desperation for help/relief in your “voice”.. Please. Perhaps get a referral from your PCP for a new pain management doctor. Call around and ask, if they take your insurance and do they prescribe. Idk what else to offer and I know im no help here. Just know youre not alone in the daily anquish. I know we’re kinda on opposite ends but its the same. Im really grasping for some helpful and useful positive words to share with you and wish I could offer hope. Just dont you EVEN give up and become a statistic! Become your health advocate. Call your insurance company. Idk.

      2. Hi Dean and Kelly
        You need to taper down as your dose is way to high, I have had 13 ortho surgeries and six fracture including compound fracture in 3 places at 12 years old. I switch to methadone 20 years ago i am 54 now, been on painkillers since 23 years old. I just had shoulder surgery and knee surgery April 19th 2018. Im telling you this so you know i am/was cronic pain. I believe you have real pain and understand your dark thoughts as I have had them too. I have tapered down to 4mg of methadone and have no constant pain ( i do have arthritis and tendonitis so it flair up but learn thats certain food or activities make it worse) which I am very happy about.
        when I was on Vicodin my moment of awakening was watching a movie called Beautiful Minds with Russell Crowe, It is then I realized it was my Brain tricking me into thinking i had pain when I really didn’t. If you watch this movie it will make you look at this possibility. I am not doubting you have real pain and its hard.
        Im just telling you my story in hopes to help you. I also do acupressure as your muscles can be locked up in your back and that hurts like hell. look for alternative medicines as these pharmacuticlals are all bad. I deal with depression everyday but not going to let it beat me. Your mind is the Key as the drug takes it prisoner and puts you/me in a HELL and we do not deserve that as the pain alone is Hell. whenever someone says to me the pain can’t be that bad I tell them they should smash there toe or finger everyday for just a year. They look at me funny and I say thats what it is like. they dont say a word after.
        I wish you the best but if you dont taper down not only will you be in pain but your internal organs will begin to fail and that is worse then pain.
        God bless and I hope this helps. Im not perfect or know all the answers but what to give my story and hope it helps just one person.

        1. Opioids do not damage internal organs, but non opioids do. Good for you that you have no pain. I did everything the pain clinic asked me to do but I was still not functional. I found another pain clinic. I take 180 morphine equivelants and am not out of pain but I am functional. I am able to get through my day and enjoy life. Pain patients should not have to suffer because of the addicts. When you truly have pain you don’t get ugh from these meds. I think it is shameful the way we are being treated. We have not been included in the conversation about opioids. Lawmakers only care about addicts and think we all are addicts.

          1. I would think you’d be a little empathetic towards addicts.
            Have you thought that psychological trauma/psychiatric conditions can cause people to get relief anyway they can. And if you think the politicians and lawmakers give a damn about us, whatever…

      3. U are probably in too high of a dose. I was at 130 and had tons of side effects. I went down 1mg a week- for a long time until I reached 75. There I had pain relief but minimal side effects. Good luck

    2. I hear u exactly. Lied to get in methadone n stayed in for 7 years. Got tired of the lieing. Then soebr 5 years in agony. Spent the last year where a pain Dr prescribed suboxone- but 3 mg daily when recommend dose is 8-16. In cibstanr withdrawal. I am going on wed to the methadone clinic- im buying some drugs so I will be dirty. Then I’ll have to go everyday n to group n individual counseling- it is all such a joke. If u ever want to talk hit me up- hey the methadone kills allll the pain

    3. U sound just like me all but I’m on the methadone an there taking me off my dr had to close an he sent me to this dr an he’s taking me of of methadone fast an nothing else I was great till I went to the new dr my pain was better I feel for u nobody wonts or can I don’t no I may have to go to a client to but that ant right having to get up ever day I’m so sorry for u I no how u feeling u here of any thing please let me no I’m in Alabama

  36. Why is my comment hidden people? WTH? People of this world EVERYDAY are apathetic liars and hateful people who look at peopl in pain like they are scum but the HATING LYING GREEDY people of this world are the true SCUM while they hide behind their wealth and greed and things and keep hating and making it hard for people who are telling the truth!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!

    1. I just had the same experience as you, tried posting a perfectly grammatically and scientifically correct experience (not to mention my 10-year battle with addiction, recovery, replacement medications, and my 2-year successful recovery period). They both didn’t show and gave no offer of explanation or even an error message. I just wanted to ask someone (who had posted to ask him if they needed help with switching to Methadone….) if they had any info at all that could help me. Maybe it’s because the opioid I’ve been so hopelessly chained to for nearly 2 years isn’t sold in a pharmacy? Not like I was trying to claim accurate, ergo, ANY conversion ratio between the two. Very disheartening to people who come here during a period of hope to enhance their lives and get shut down with no explanation. Great job.


      This is a lie. remove it now please or I’ll report it.

    3. It’s called discrimination and it is everywhere I was an addict for 10 years using pills and heroin then I go and try to get help and I find that the methadone treatment program is the best option for me if I go out and try to find a job the employer’s will discriminate and a criminal background no felonies but several misdemeanors I have actually done this and I am having a very hard time trying to find a decent job I’m not talking about McDonald’s or Walmart but like a career I go to a treatment program where I live only about half the people there have jobs and that’s because they had gotten their job before they got on the program it is downright ignorant for people to discriminate when you are trying to get help for yourself that’s all I’m saying…

      1. As an employer, I can tell you that hiring addicts is risky. There is a chance of relapse, not showing for work, stealing, etc… There is no justification for committing crimes. Just because you are addicted to drugs doesn’t mean you have to live like a scumbag. I’ve had plenty of issues with addiction myself, but still tried to live my life like an upstanding member of society. People need to take responsibility for their actions, whether they were messed up on drugs or not during the offense doesn’t matter. Keep working on your life, and if you have to go work at McDonalds for a few years so be it. You got to start somewhere.

        1. James Bowser, I agree with you. Any thing John did in life was of his choice. He blame his problems on society. I didn’t tell Dr. Fudin the length of time on methadone. I want to say, if you want off, then tell your Dr. If he won’t help, keep trying Believe me, I was surprised that 60 mg to 30 mg was tolerable You think not, but try it after talking to your Dr. and ask to get his opinion It feels good, John, to finally have a clear mind. It’s uncomfortable, but with God’s help, your desire to be free, everyone can get off. I’m 3 months short of 70 years old, so there’s no wrong time, but start soon. Life is short and we must stop making excuses.

    4. I’m positive that it’s litteraly easier to find a needle in an kilometres bale of hay. Than to find a Dr., who is truly empathic, and educated enough to tteat those of us who are in real pain. Most of them base a lot of diagnosis by reading thimgs others posted. I personally have had a combination of injuries and illnesses that make extremely difficult to for myself what the origin is.

    1. Toxic; I cannot allow a post giving medical advice. The conversions and information you provided were inaccurate. Equally important is that methadone metabolism is very patient specific so even if there were a universally acceptable conversion ratio, the half-life varies from 15 hours to 60 hours, up to 150 hours in genetic outliers. And, that doesn’t account for the countless drug interactions because of the way it’s metabized.

      1. I have a question that has worried me for some time now..the doctors in TN. Know NOTHING about methadone…I had a spinal cord stimulator put in, last June. I was told that the methadone will be fine to stay on during surgery, and added pain meds will achieve the pain relief i need. They were WRONG!! I laid in the hospital 3 days and nights SCREAMING IN SEVERE PAIN! I am on 120mg…and I’ve had 4 back surgeries, and have significant pain…my question is, should i have stopped the methadone until I got past the “painful period” after the surgery? I feel like the methadone blocked the othere med..they gave me. Morphine, I suppose, in I.v…..and on the second day, they gave hydrocodone every 4 hours…which is like candy to me…I have a BIG SCARY fusion coming up on L3,4,and5 soon….should i DISCONTINUE methadone for a few weeks after surgery to be on normal opiods???? I’m so worried…I don’t wanna be touched, but my pain and weakness is horrid

        1. I had 6 titanium brackets put on my spine “L1-5 and what the doctors did not tell me since I was on methadone that I also would wake up and recovery and feel everything with no pain relief and I also have to undergo a double mastectomy and I rather die while being on methadone I have been titrating down now for one year and I’m only at 51 mg and no rehab will take me and they damn sure don’t accept state insurance so I’d have to pay upfront close to 20 grand to try to get methadone out of my system but the doctor got his $250,000 for doing my surgery didn’t care about the pain I suffered I woke up in recovery screaming I pulled every tube out of me even the sewn in drain tube out of my neck and I walked out of the hospital out of my recovery room!!! Only thing

        2. You do NOT want a Methadone addiction ! Ever! It is Much worse Than Heroin to get off of !Get away from it , at all costs . The doctor should have invited you to research this .

          1. What is the other option from metherdone is morpine any good to come of heroin and roughly how much should I take and what I’d difference please if you could help plz

        3. It didnt block anything. There is no naloxne in methadone so you can take other pain meds on top of your methadone dose but there is increased risk of side effects and respiratory depression. Speak to your doctor. Get well

      2. I have a question that has worried me for some time now..the doctors in TN. Know NOTHING about methadone…I had a spinal cord stimulator put in, last June. I was told that the methadone will be fine to stay on during surgery, and added pain meds will achieve the pain relief i need. They were WRONG!! I laid in the hospital 3 days and nights SCREAMING IN SEVERE PAIN! I am on 120mg…and I’ve had 4 back surgeries, and have significant pain…my question is, should i have stopped the methadone until I got past the “painful period” after the surgery? I feel like the methadone blocked the othere med..they gave me. Morphine, I suppose, in I.v…..and on the second day, they gave hydrocodone every 4 hours…which is like candy to me…I have a BIG SCARY fusion coming up on L3,4,and5 soon….should i DISCONTINUE methadone for a few weeks after surgery to be on normal opiods???? I’m so worried…I don’t wanna be touched, but my pain and weakness is horrid

          1. Methadone does not block other opiods??? Sir i have been attending the clinic since 2005. I am a counselor as well as an experienced dryg addict. I snorted 6 oxy 40,s while on 130mg of methadone and felt nothing.

          2. I have been working in health care for over 25 years. I have a masters in nursing and continued on to become a NP and the information that I’ve always been told is that methadone does block other opioids. I would not take anyone’s advice on a site online. Schedule an appointment with a doctor that works in a methadone clinic and he will give you free advice and at least he will be upfront and honest with you. Please don’t just take anyone’s word. After talking to a methadone doctor then talk with your doctor and if he isn’t willing to make you a promise to keep you out of chronic pain then please find another doctor. Some doctors assume that 120mg is just a extremely high dose of methadone and it is but if you have been on that amount for years then most likely you would definitely need something more for the pain. I am in no way telling anyone to take my word I’m just hoping to give enough information for you to be able to find the correct answers for yourself by going to other doctors. You can go talk to a doctor in a methadone clinic for free and they will be very upfront and honest with you. Don’t settle for one or two opinions get several different opinions from different doctors that deal with methadone and that doesn’t deal with methadone. Just remember every case is different and no one deserves to have to deal with excruciating pain after major surgeries. Good luck to you all and remember it never hurts to get several different opinions. Good luck everyone. And please understand I’m not giving you advice about medication I’m giving you advice about getting different opinions from different doctors that deal with methadone and doctors that don’t deal with methadone. Good luck

          3. It Matters not how many masters degrees you have.Many Methadone Maintenance patients that I have Known Personally simply take methadone and then go get destroyed on Heroin or Morphine tablets. It is a poorly kept secret that an addicts get blasted on all manners of opiates while on a dose as 120 on methadone. It is a fact of life in the recovery community.

          4. Im taking 72 mg of hydromorphone contin per day and want to switch to methadone at a clinic. How much methadone will they prescribe to replace what im taking in hydromorphone contin. Ive red alot on internet and just want to make sure they dont give me too much

          5. ive been on methadone for 8 yrs on various doses and come off of,it twice as well. methadone does not block other opiates. it increases your tolerance to the point it would take a very high level of other opiates to get high or feel relief. i know. ive done my own “personal expirimentations” on this earlier in my treatment.

      3. Suffering addicts who come here to find information on does conversion during possibly their ONLY, brief period eof hope and a light at the end should at least see a comment posted here that tells you what you are allowered to say or not. I was incredibly disheartened when I tried to post 2 personal, scientifically and gramatically correct (without suggesting drug interactions etc. would not influence a major decision like methadone) and greeted with no message explaining why it had not been posted.

      4. Jeffrey, You say there are “countless” drugs that interact with methadone. Would you please list the drugs that reduce the effects of your methadone dose. I am especially interested in the interactions between nicotine and methadone. Please explain the pharmacodynamics of these two drugs as to if and how nicotine can reduce the effects of your methadone dose.

        1. Methadone is metabolized in the liver by several different enzymes known as cytochrome (CYP) enzymes. They are designated as CYP 3A4, 2D6, 2C9, and others. Certain drugs encourage the liver to make more of these enzymes – such drugs are called enzyme inducers. Any drug that is metabolized by an enzyme is a SUBSTRATE to that enzyme. Any drugs that induce the same enzymes responsible for methadone metabolism can lower the methadone levels. A list of substrates, inducers, and inhibitors may be found at

          1. Thanks but what am I looking at? So every drug listed makes methadone not work as good? Thanks

  37. I am writing this on behalf of my mate as he cannot use his phone,he has been prescribed methadone now for over a year,he was getting 60ml daily but due to a mix up with the doctor his prescription was not wrote out correctly and he missed the three day window,he was given an appointment to C the doctor and theye only gave him 20ml for two days and 30ml until he sees the doctor again,is this legaly moral and correct use of his powerstuff to prescribe as my mate is suffering and had to use opiates to overcome the massive drop in dose. Thanks for taken the time to read this.

    1. Chronic pain patients should be in a separate category for prescribed opiates. One’s ability to lessen pain, or better yet, controlling pain, should not be taken away! Reduction of prescribed amounts is only thee first step in taking all opiates away. I’ve yet to hear what their idea is as an alternative plan for people in chronic pain? Is our quality of life only of value to ourselves & those who love us?! It’s become clear, it is, we are, NOT important to “the powers that be?!” What is our alternative choice? This isn’t an alternative but it may be helpful. A drug called: Cymbalta, marketed to people who’ve become depressed with chronic pain. (There are generic brands available now too. I was originally prescribed it when there wasn’t.) It’s basically an anti-depressant that also helps with some pain relief.
      It’s too bad all thee chronic pain sufferers couldn’t come together, make a stand, & to be heard, it might make a difference!!?! I know if I didn’t have a Son, it’d be just too much! Hanging around here, every single day & night in pain…that’s not a life of quality, The knowing that tomorrow won’t be better, that today & all your tomorrow’s will be debilitated with pain…unbearable! I hope & pray we’re not left with only the raw nerve endings of our all encompassing pain! For me, losing my only sibling (a Brother 3 years my senior) to ALS & both Parents to cancer with-in 17 months of each other, (just 7 months ago),certainly doesn’t help. Denied any type of anxiety medicine because ” I take opiates” accumulated into a nervous breakdown. We must all find courage to have Hope for the Future! (And see about getting a Rx for generic Cymbalta!) I hope my post helps with relatability & a new idea to battle “being bummed out, that you’re stuck with chronic pain” prescription,

      1. I was on methadone, hydos, and clonazepam for over 16 years and had them just taken away from me and was placed on Suboxone. I am one of the few that suboxone and buprenorphine tablets just didn’t help and made me feel so damn sick all the time. This occurred in March of 2017 and just June 1st, 2018 I was changed back to methadone — to 5 mg once per day. I was on 40 mg of methadone. Obviously 5 mg is not enough as for some reason I feel as though I am in withdrawal – I could tolerate about 1 mg of Buprenorphine a day and that’s it…would the buprenorphine still be blocking the effects? From my research I don’t think it should be.
        I feel like being taken off of all these drugs at once has given me permanent brain injury — very serious here – as I literally cannot wake the hell up mentally – I forget everthing and anything. This has been a nightmare. I know that Benzo’s can cause this, but I was on the Benzo for all these years and now they suddenly are taking them away from pain patients and are causing severe long term cognitive decline and brain injuries. I know from using a benzo with my methadone that I was never in any danger of respiratory of heart failure — they have to look at Quality of Life instead of Longevity. Screw longevity when the quality of my life is this low I have no desire to live long – in fact I joke and say it is my curse to live long.
        I just feel for the Pain Patients who are totally being ignored — I cannot even write a coherrent paragraph here, but I am suffering big time right now and the major problem besides pain has been complete Lack of Motivation and not being able to think – it appears I just can’t Wake Up. Does anyone else understand? I know I am likely a very rare case. Thanks

        1. Abrupt withdrawal from meds like Ativan ie: benzodiazepines can cause permanent psychosis according to PDR. You obviouslly were spared that but the physician who committed such an awful action & risked such an outcome needs education and review from his licensing Board..please report him or her to AMA & his particular Board for his pain mgmt specialty I’ve always been too scared to do anything against the physicians who have harmed me but we have to fight back.We should get a patient advocate to help get the care needed . Try your local large hospitals for in or outpatient programs. Supposedly they help us with all care when suffering severe chronic illnesses that cause pain and exhaustion. Heh… my area programs turned me away but you may have better luck…do zipcode search… Nonprofit site- .It is so evil, to pretend to be caring professionals who seem to hate those of us who require opiates to survive incurable, unendurable pains despite exhausting other options. I think the gov’t is trying to eliminate us pretending to stop deaths by overdose. Suicide rates have increased 29% since they’ve been witch hunting good pain doctors & restricting chronic pain care.

        2. I just want to connect with someone. This is the first place I have ever found people with similar experiences to mine. I’ve had chronic pain since I was 32 I m 47 now- and feel old before my time. Brief history- was on large amounts of narcotics- fentanyl oxoycitton with some psin relief. My Dr got into trouble prescribing pain killers so I went into refill n she just told me we should wait n see how I was without the pain killers. I started crying- knowing how much withdrawal n pain would hit me but she wouldn’t change her mind. I had never failed a drug test. After the worse week of my life a friend let me have 30mg of his methadone. Couldn’t find a Dr to prescribe for pain so o learned what I had to say to get into a drug program. It worked but at 130mg i had tons of side effects n didn’t know that reducing would make it better. Plus after 7 years I was tired of “being a drug addict”. I went off- a mg each week n hot off with no withdrawal (of anyone wants info about that let me know). Then I spent 5 years wuth only lyrica n cymbalta for pain relief. It would hardly be fair to say I was living. I couldn’t go to the grocery store much less lead a life. I found a pain Dr willing to help- He put me on suboxone- 2 to 3 mg a day. Unfortunately I went through withdrawal continuously. So here I am about to enter a methadone program- again as a drug addict. Sometimes I can’t find a reason to keep trying. I have no quality of life right now. My email is Would love any advice or even to talk. Hope u all find some relief- take care

    2. I don’t understand why you can’t voice ones opinion or fact to ones experience in methadone. If you are not being treated fairly or right, voices should be heard and comments should be made. Others needs your help to feel or believe they are not alone in this cycle or battle of addiction. I myself wants to be weined off.

  38. Can someone experienced please help me? I’m on 75 mg of methadone. I was on 150 but tapered down and have been on 75mg for about 8 months. I want to get off & I went too fast & tried going from 75-65 in 1 week and for some reason I threw myself into withdrawl &had to go up from 65-75mg so have been afraid to decrease anymore after that happened. I’ve been clean since 2/9/16 started methadone 2/2/16. I want move to mexico and there is no methadone there so would like to come completely off. I’m so weak when it comes to withdrawals &handle them terribly. A Lil sweating will over the edge. What is the quickest smoothest way to come off with as lil withdrawal as possible? My email is
    Thanks so much

    1. Hey Seneca,
      I was on 55mg for two years and started tapering not long ago. I was able to taper down 1 mg per week down to 23 with absolutely no withdrawls or discomfort. Everyone’s body reacts differently so I would just make sure you’re consistently talking to your doctor about any negative symptoms and don’t be afraid to put the taper on hold until your body adjusts. Just go slow and steady.
      Now that I’m at 22 I’ve slowed it down to 1 mg decrease every other week or so depending on how Im feeling.

      Trust me, if you find a taper rate that’s right for your body you shouldn’t be feeling any discomfort. I’ve been able to continue working and going to school all through mine.

      Good Luck with your taper and move to Mexico, im trying to get clean so I can move down to Costa Rica myself 🙂
      You got this

  39. my name is Danny I have been on oxycodone 30 mg an oxycontin 80 mg for 15 years from the same doctor do to my chronic pain my main question here is I do not be need to be weaned off of medication I need my medication for my pain my main question is if I take 40 or 45 oxycodone 30 mg at once will it in this pain and suffering I’m going through that’s my option right now and I plan on doing so but I don’t want to do it if it’s not going to work I want to end my life at this point as soon as possible thank you and God bless see you on this side of the other or the other

    1. I hope you don’t do it.. I’m sorry withdrawal sucks and chronic pain people get the shit end of the stick most of the time..

    2. Awe,please don’t say that but I understand your pain. I had a back spinal fusion and I am crippled now. Barely can walk for 5 minutes now when before the surgery the pain was there but Nothing like THIS PAIN I feel every damn moment of my days,I wouldn’t be here if it wasn’t for my daughter…but please hang in there,it Will get better. My family has had several suicides and it just hurts everyone! Xoxo

    3. I hope you do not consider doing this, let me just say that opioid medications do complicate your emotions and what you are feeling may not really be you…it may be the result of years of medication suppressing your endorphin system causing a depression. As time goes on while using these types of medications it suppresses your natural ability to be genuinely happy thus causing adverse thought or action. I would definitely talk to your doctor about what your going through, and maybe a family member or friend. Its not worth doing what your thinking of. I would hate to hear this happen. Everybody deserves to live, and happily. My thoughts and prayers go out to you. God Bless.

      1. I have been on methadone for a week on a split dose of 15mg in. Am and 15 mg 12 h later have missed. Dose do to the hospital not sending my records to clinic i have call the hospital and the methadone clinics as still nonothing i mean i have sweats. They have also call cps and flu my son to icu due to the methadone and herion in his system. I feel as i have made a bad move will i lose my son

    4. Hi Danny,
      I hope you didn’t en your life! I know how it feels to b in pain every day all day that you can barley move or want to get out of bed. I was taking pain pills for the last 15 years for lupus and Crohn’s disease , I was on Fentanyl patches 200 mcgs and oxycodone 80mg 4x a day and I just got off of all of it little over 30 days ago and my doctor now has me on methadone and right now I’m at 110mg and I still have pain but it’s so much better than it was when I was on the pills and patch. I go up ever couple days by 10mg . There’s such a stereotype when people talk about methadone they think of attics and so it took me a long time to accept that my doctor wanted to put me on it for chronic pain and I’m telling you it was the best decision I’ve ever made in my life. Please talk to your doctor first before you think about taking your life I had those thoughts at one point too and I was open with my doctor and he thought methadone would be the best thing for me and it has been. I know taking your life seems like the best decision to make but it’s not talk to your doctor you can be almost pain-free with methadone and you can start living your life again I have and I didn’t get out of bed for months at a time so please talk to you Doctor.

    5. I would hope you didn’t end your life. I know the real pain and your life is worth it. No matter what. Message me

  40. Hi I’m at a clinic for about 6 months now, been on 120mgs for a while now. I can’t afford to go anymore so they have to be dropped 10mg every day…… So in 12 days im done. Been on it before I wrnt there to for a few years. I’ve never dropped that fast and I’m scared what I’m going to go through. Can anyone give me any tips or help please, thank you .

    1. Stay focused and you should be fine. I imagine there may well be some discomfort but be prepared with the right meds and KNOW you can do it.

      1. Hi I’ve been trying desperately to find a methadone mg to morphine mme. I’m afraid my husband is going to die. The charts don’t make sense. Some charts say 90mme is equal to 20mg others said it’s 5 mg equal 90mme. There must be an estimate. Thank you

        1. I’m going thru the same thing,switching from methadone to an opiate and the charts are all different, it’s ridiculous bc I’m dying in pain and it’s been 3 long years. The fact is there isn’t much data on it and what there is varies so widely for Tons of variables. I’m so sorry that your both going thru this,I wish you hope!

    2. Email me, I can help guide you, free, I don’t want $ , 17 years experience on meyhadone… won’t beleive me when I suggest …….. I wish 15 years ago I knew this. Easy off! ….

      1. Any tips on how to come off a 150mg Oxycodone habit a day? I don’t have any methadone or anything else 4 that matter. Any tips would be appreciated

        1. I know there is a lot of negative clout about methadone but it saved me, I was at 180-300 mg oxy and I couldn’t taper myself no matter how much I tried. So I went to a clinic where they switched me to methadone, no withdrawal, then I have been tapering 2mg a week so I don’t experience any withdrawal. But stay on a low dose because it can cause weight gain, blood sugar problems as well as high blood pressure..

        2. Take it one day at a time. get a solid support team, especially whenever you go haywire and really need someone there. To coach you or hug you. If you can get a couple of different levels of the same pill this could help alot . If you find you not understanding how. To do the doses in smaller, it is no shame asking a doctor for help i have never heard of one tossing out for asking for help to come of pain meds , unless you were filed a restraining order that stay away. sometimes you find a nice doctor that will help you come down off the medications over a couple months. This isn’t likely the case in most situations. These are my suggestions:
          Week 1: 4 each day as you have been taking normally.
          Week 2: Lower to 3 each day it is your exactly when and how much but only 3 a day.
          Week 3: Lower to 2 each day and like week 2 all of the when and how is your decision.
          Week 4 and on: here on you might have different dosage of different kinds of pain medicine to also help you come down. If not then just keep taking 1 a of day until you’re fully out or until you’re just saying why am I taking us finally and throw it away down the toilet you are stronger than anything else you will survive this over anybody. Put in your head and u tell your heart and sometimes you have to keep repeating it that you are stronger and you can and will do this! Just telling yourself this can be the biggest battle!
          Any advice taken I am not liable for I do so without vicious will, i do this bc so many wanted knowledge.

        3. Hey I noticed your post. Have you been able to kick it? Did you ever get any good advice for withdrawal? If not feel free to hit me up. Ian

      2. So what’s your “easy off”? I’d love to know. I take methadone with Norco as back up, buy my state has decided that my pain management doctor can’t give me this combo anymore. It’s been 2 weeks and instill feel like I’m going through withdrawals. My joints each any help would be appreciated!
        Thanks, Sami

      3. Hi Greg,
        Could you please provide me with your email address? I took 120mg’s of methadone per day for two years for severe chronic pain, and I began having so many side effects and/or other health problems (however it worked better than any other opiate for relief of my chronic pain).
        I weaned myself off of it a year ago, lasted about three months, but I still had all the same negative effects.
        I’ve been taking only about 10-15mgs per day over the last year, plus a load of dilaudid, and I’m still stuck with the side effects I developed over the first couple of years from the high dose of methadone.

        My doctor is baffled about it, says he’s never seen anyone as bad as me. He is licensed to prescribe, although he has very few patients on Methadone

        I’ve been desperate for help for over three years now.

        Best regards,

        Any advice would be greatly appreciated.

      4. Please email me the easy off info you know of. I just got started on methadone and im prepared to be on it no more than a year because i want to be free from drugs! Obviously im afraid of being sick but i realize i will probably be a little uncomfortable unless you know of a miracle remedy for weaning off.please help me.Thankyou!

      5. I’m getting clean from heroin I am on 45 mg of methadone A-day when will I be able to go down and is 45 mg a high dose? It keeps the withdrawals completely gone and to be honest I don’t think I need to be this high of mg. Help I just want to be clean and free of it all

      6. Hi, I’m trying to help my husband. I’m worried about him. He has been on methadone for 3 years 80mg. He decided 3 days ago he was done, just done. I’m really proud of him but I’ve heard terrible things about coming off cold turkey. But many things on the internet are conflicting. Can you email me and help me so I can help him. I would really appreciate it.

      7. I’ve been in chronic pain since August of 1996. Looking for the best methadone to MME equivalent IS frustrating. It’s the “half-life” of it in your system that’s complicated & confused any sort of accurate conversion for MG’s to MME’s. Regardless, my half-life is residue of the drug in our bodies, not pain relieving amounts. (Like THC in your blood/urine long after consumption.)The benefit of pain reduction from Rx only lasts about 4 hrs. My dosage went from alotted 20mg 3xday to 10mg 3xday. Yesterday my Rx was written for 10mg for entire day!!?! Debilitating pain day in day out isn’t (can’t be?) understood by people that haven’t experienced it! Our pain relief is being controlled by the gov’t. Worse, they’re not Doctor’s or even Insurance adjusters that (*key) don’t bother to look into our medical history’s. Everyone is lumped together into the same category, opioid users. It’s become obvious their end game is total elimination of opioid use!!? With chronic pain knowledge of; tomorrow won’t be better, How can it be a good idea to take pain relief away?!
        I’d like to know what you did to no longer take methadone & have any sort of quality of life?!

      8. My Dr wants to switch me to methadone because insurance will not pay for the OxyContin I have been taking. I take 60 mg of OxyContin three times a day. I take it for my back. He says insurance will pay for methadone but not OxyContin. Thank you in advance for your time

      9. Can you please send me your contact info? My fiance are both tapering down from methadone and are reaching a point where the detox symptoms are causing us to slow our pace. We would like to continue at the same pace if we can find a way to manage our symptoms. My email is

    3. I have chronic pancreatitis and have had it since right after the birth of our 3rd daughter. I have tried so many different pain meds but nothing works like methadone. I am now finding that doctors are cutting my dose for no reason at all and I am having the hardest time. All I want is to go to the grocery store without crying at home for hours after because I hurt so bad. I just feel like giving up!! I have 4 teen daughters and they still need me to be their mom!!! I feel helpless!!!! Is 90mg a day insane I have been on it for 8+ years?

      1. Hun 90mg isn’t definite not an insane dose people are on as high as in the 1 and 2 hundreds for pain. Not talking about methadone clinics where addicts unfortunately need high doses i.e 100mg and above and it’s like taking a tylenol to them. Any way there is a lot of wiggle room for dose adjustments for the meth but tell your pain dr. Exactly how u feel on the 90mg dose which I assume is 30mg 3×daily…. if u want to talk more email me at

        1. Agreed, im on 150 a
          Day, was 200mg at one point. Pick up once
          A week and away we go! Some elple meed more, some less. These amounts are not reserved for hospice settings. I work full time 10 hours a day 5 days a week. If the methadone hit me that hard, I wouldn’t be able to sit at my desk and type all day.

        2. I have an inoperable vertebrae collapse condition since 1993. I was born with my spine only partially connected at bottom. When I move, my spine moves and this causes severe sciatica. A neurosurgeon diagnosed me via a cervical kilogram test after many other doctors could not diagnose me from 1993 until neurosurgeon found my problem in 1997. He said surgery was not an option and said to find pain management with pain medications. I went to a pain clinic in 1998 and was put on 120 mgs of methadone per day. Took it for 14 years plus morphine prn for breakthrough pain. The idea was to keep on top of the pain. Still I had severe sciatica and it would wake me up and last all day until I finally passed out from exhaustion due to crawling around on the floor, pounding parts of my body that didn’t hurt to detract from the pain. It was like toothache pain the worst pain and constant. Once it came, nothing I did it took helped. I could not stay still yet moving around didn’t help either. Luckily, I would only get it for a day at a time and I had bouts of it approximately 5 days per month. Once I slept I would wake next day and sciatica was gone but my body was sore for 2 to 3 days. Then I would be so worried about when it would come again. It was no way to live, but the methadone did help me not get sciatica as often as I had it prior to being diagnosed. From 1993 (onset) until I was diagnosed on 1998, I was told I just wanted narcotics and it was imagined all in my head. I never liked drugs that clouded my mind and prior to this problem, I was athletic and I got my highs from running. In 1981, I ran the mission bay marathon in San Diego after training for it for three years. I was the 22nd woman to finish the 26 mile run out if approximately 1000 women and I felt the best ever then through exercise, both physically and mentally. I had no idea I would have this horrible thing happen to me, but in 1993 after moving to northern Michigan, I began to have pain deep in my lower spine and buttox that was hard to explain and I had just found a job in my field (hard to find in a small town) and then onset of collapse of spine began. It took 4 years of tests and not being believed until I was referred to a doctor who found my problem. He said surgery would never be an option. So I took methadone after trying many other meds that did not help at all. I did feel 130 mgs was excessive but I did what I was directed to do by pain specialist. After 14 years I heard of another specialist and after consulting with him I left first clinic and began going to this other doctor as he felt I would do just as well with 90 mgs and he had other suggestions like good shoes, Pilates ball and a wonderful back brace. He helped me to wean to 90 mgs and I had a great 2-1/2 years with only rare bouts of severe pain with this Dr. Unfortunately, he closed his clinic in Jan. 2014. Then my primary care physician had to take over prescribing my methadone, a med she did not normally write for. She got me down to 70 mgs in about 18 months. Then, all Hell broke loose here in Michigan and all doctors are scared to write for pain meds. I kept weaning and got to 40 mgs, which was really just as effective as 130 mgs I started with in 1998. I always have low back pain, but have learned to cope with it even at 40 mgs a day. Then I was told I could not get the methadone and in Jan of 2018, not only was I abruptly cutoff but am now treated as a drug addict and my sciatica plus nerve pain has returned but I can not find any help and have looked all over the state. I am 67 years old and now someone else gets to decide I can live with the pain. Too bad for me. Doctors are afraid to give any narcotics at all. In April of 2017, I went to see neurosurgeon who diagnosed me with a fresh MRI in hand. He said no way could I survive a surgery that, at best, would only relieve 20% of my pain and 4 months of what he said would be horrific pain, post op, would not be something I could get through. He said I would need rods, screws, and cages and my body would most likely reject the steel so he said surgery would never happen for me. Too risky and I believe him. So here I am still looking for someone to prescribed methadone. Even 20 mgs a day would be fine. I have tried shots, many other meds, physical therapy, acupuncture, and nothing works like the methadone. It just seemed to be the best med and I did not get a high from it. I am worried what I may do now that I can’t find it, even at a low dose. I never misused it or abused it and can not understand why I can’t have it. I do not ever drink alcohol or street drugs so what is the risk. If doctors had been more proactive with those they gave methadone to, kids and others would not have abused this med by mixing it with bensos and alcohol and would not have died as a result. By proactive I mean counting pills and urine tests every 28 days or more. I would insist on a doctor testing me and counting my pills and even calling me in before scheduled appointments to make sure I am adhering to the rules. Instead I fell between the cracks and my life is going downhill. I still have bad withdrawal symptoms even though I have not had methadone since January 2018. I feel I will never get back to who I was before I took methadone and I am angry that I worked 34 years only to retire into a life of Hell. I am considering ending my life at this point because of how I feel, the pain, and being treated like a drug addict. Let me finish by saying I have other medical problems like ADHD, PTSD, ANXIETY NOS and OCD. Now I have agoraphobia and just sit here alone and pray to not wake up tomorrow. Why did this happen when I was willing to wean down? I would love any advice you may have. I took too much for too long to get over it. I want this drug only because it was what helped me and I have tried too many others to mention. Now I can’t even enjoy my retirement. My family are all dead. My marriage died in 2015. Yes, I see no reason to be here anymore except I have two cats whom I love and do not want to leave. I needed to return to work as I owe 50 thousand dollars on the home we bought in 1997. I can not work if I can’t count on when I will or will not wake up with sciatica. I kayak and bike ride for exercise occasionally, but could not run once around my house now. Maybe all that running was not such a good idea as I am filled with arthritis, fall down a lot and just hide in my house afraid to even go for groceries. Since no methadone, I have gone from 135 to 104 pounds. That would be good but I lost weight because I do not care to fix food anymore. I think the doctor who gave me 130 mgs a day of methadone, should have his license taken away because I now know 40 mgs would have been just as effective for me. That is my story and may not have been the same for others, but using it for so long and being abruptly stopping was a bad thing to do to me and no one in medical profession seems to care. Any thoughts or advice would be appreciated here or to my email.
          Thanks for reading my words.

          1. Hello I’m so sorry about what you’re going through I know the feeling all too well. Is there not a methadone clinic in your town or nearby city that you can go to right now the law just passed and all methadone clinics are free and state-funded. I would try that and hopefully you will get some results. my prayers and thoughts are with you!

          2. My comment to another person applies to you, too so since it is still here,
            So many of us are going though this Hell as govt via Fascist dictates have scared good pain physicians into doing harm by weaning or discontinuing life saving opiates….but we have to fight back.We should get a patient advocate to help get the care needed . Try your local large hospitals for in or outpatient programs. Supposedly they help us with all care when suffering severe chronic illnesses that cause pain and exhaustion. Heh… my area programs turned me away but you may have better luck…do zipcode search… Nonprofit site- .It is so evil, to pretend to be caring professionals who seem to hate those of us who require opiates to survive incurable, unendurable pains despite exhausting other options. I think the gov’t is trying to eliminate us pretending to stop deaths by overdose. Suicide rates have increased 29% since they’ve been witch hunting good pain doctors & restricting chronic pain care.
            Do get helo if truly suicidal but if you mention that or ANY past or current anxiety, abuse, depression or also any problems with falling …. they will use it against you to deny pain meds. Especially if sent to psychologist for testing…. they are not on your side. Get help seperately without any chance of it getting back to pain clinic. This is a crazy, evil time when pain patients are seen as weak, crazy, junkie, useless, time/money wasters by most doctors & govt is pushing regulations to push us over the edge. Fight.

      2. Hi,
        Doctors are now cutting doses because of the new federal
        Limits that state patients can only be on 90mg of morphine or it’s equivalents. I’m not allowed to say what those equivalents are but ask your doctor and he will tell you as it ranges and there is no definite number with regards to methadone. But in my state the max amount of methadone a pain patient can receive is 30mg in one day. Actually the max is 25mg but if a doctor feels the patient needs 5mg more he can write a letter justifying it. If doctors prescribe more than this they can lose their license which is why doctors are lowering doses like crazy and in some cases, not prescribing certain opiates. I talked to my pain doctor in depth about this. His hands are literally tied and he cannot raise the dose anymore. If you want more info look up the new federal limits with regards to opiates. This is all due to the opiate crisis and politicians trying to make a “change” so these new limits have all been imposed. I’m not sure how many states it has affected yet but soon it will affect them all so if you are on a high dose of opiates don’t be surprised if your doctor starts lowering it. It’s terrible that they are penalizing pain patients. Meanwhile if you go to a methadone clinic, which is supposed to be for addiction, there is absolutely no limit on how much you can be on. I know someone who is on 300mg which is crazy, meanwhile we are limited to 30mg?! They say that pain patients are the ones selling their meds which is why this new limit is being imposed but I know people on the clinic who sell their take homes so it really is ridiculous.

    4. By now you should be feeling the full effects of that fast of a drop, it takes about 1 month, you will have intense back pain and lethargy, your temperatures will rise and fall, and you might even get the typical wd stomach pains but it lasts forever!! Don’t drop that fast, spend the money on going every 3 days if you have to or even every week just to keep it in your system for at least another month to stabilize:

    5. Dear trouble girl,
      Unfortunately ,i am a walking dictionary of information and my information is good and accurate in my opinion better than anyone i know. You’re right and some of these people here [i would like to say something else] should keep their mouth closed.

    6. I had to do the same. 120mg to 0 in 18 days. My withdrawals were so bad that I went on suboxone 8mg and weaned down to 1mg over two months and now two weeks off the subs and still feel like crap. However, staying busy, walking, kratom and a natural sleep aid is helping. I hope you are hanging in there! We can do it!

  41. Everyone is different. Everyone handles and feels pain differently. Due to chronic pain, I have tried a lot of meds, at one point I was taking 3 Lortab and 1 10mg methadone….dropped all other meds and took 40mg of methadone a day in two does. It worked so well I had banner years with my business. Methadone is also cheap. The so-called opioid crisis is NOT due to real patients taking pain meds to have some sort of quality of life. I strongly suggest anyone who has trouble with addiction and does not need so many mg of anything and is simply strung out by their own doing should simply go to a methadone clinic where the pros are who know what they are doing. I changed every doctor who wanted to prescribe MS Contin…Morphine and would not give me methadone I simply acted as professional as the doctor did and continue to seek what worked. BTW I do not know how to buy drugs on the street. In the last 20 years that I have been on pain meds, I got married raised two children sent them to college bought a home, some Harleys, started a business and so on, I am still married…my kids are doing well.

    For me methadone did it well and I would have never lasted on anything else. One thing methadone does that most doctors don’t like is methadone raises your blood pressure. So, remember this different for everyone….things are changing for me due to I was born with heart disease (murmur) now I need two valves fixed…the first thing that happened is I was discharged from my pain clinic for using CBD oil…the clinic cleared house after it was sold to a huge company…so its clear that clinic did not have my health in mind at all.
    I needed a pain doctor….I will have open heart surgery to correct my valves…since the first doc I saw at the clinic I was going to was so good to me in 2013 I found him again and wemt to see him…..he was the one to start me on methadone…since he can no longer prescribe methadone in the state of VA where his new office is I live in MD….now the bad part for some reason he thought 10mg of oxycodone will keep the withdrawal away and help my pain…I waws on 40mg of methadone a day with 20mg of oxycodone a day…he wrote me up for 4 10mg oxycondone a day…OK that worked for the first 12 hours….OK I found another went there was treated so well…..they put me on th eOpana 15s X 2 aday and 4 15mg oxycodones a day…OK this worked…no withdrawal and pain levels back down…work back up life is good again now for the surgery in two weeks.

    1. Thank you for sharing your story. I have been on methadone for a couple years and it is the only thing that helped me with pain and it is very consistent. Not sure what I am going to do now bc my Dr. said New York State is changing the law here starting 1-1-19 and will only allow a maximum of 90 mg of per day of morphine equivalent. I am taking a total of 50g of metheone per day now and don’t know what that equals in morphine. I am also going to get my medical Mary Jane card next month. I hope it will help so I can reduce my pain meds.

    2. As a chronic pain patient for 20yrs and as someone that worked in health care until last year I feel maybe I need to say this. I want to preface this by saying I don’t think this is fair and god knows I have went through my own hell. You have been very, very lucky up to this point going from one doctor to another and another. I’m guessing you crossed state lines somewhere. Unfortunately this is considered “Drug Seeking” behavior. Yes I know you are looking for a doctor that will keep you on what works, but you can thank the drug abusers for this and it’s been this way for many years. I would love to seek out another pain doctor, but I don’t dare do that. You can’t even mention what medication has worked for you. If you go to a new doctor and say pain drug “b” works best this is another drug seeking behavior. Those that actually abuse drugs do this wherever they go. They will be “allergic” to every drug, but the one they want. It’s not fair, but life is not fair. If a doctor, which probably won’t happen today asks you specifically what has worked in the past then its fine to mention drug “b”. It has always been this way, but with this daily attack on opiod addiction the doctors are feeling the pressure. Most chronic pain patients never abuse meds something like fewer than 5%. You and I should be able to go to another doctor when your doctor only uses one medication, or in my case treats all patients with the same drug and actually does no pain management. Oh and by the way. All of this opiod abuse is NOT prescription meds. It is Heroin and fentanyl. The 600% surge in overdoses was caused when all the family doctors sent their chronic pain patients to pain specialist and they quit writing loratab and percocet to everyone that said they hurt. This ultimately dried up the availability of these drugs on the street (which was alot safer to abuse) and this caused all those on the street abusing oxycodone to switch to heroin/fentanyl. This ain’t oxycodone and that has led to the massive amount of overdoses. So it was the lack of prescription drugs that caused todays problems and it started around 2012.

      1. I certainly hope you mean to say this is your opinion based on your experience in whatever part of country you live, because the statements don’t pan out to the facts.
        While Heroin and Fentanyl are what’s causing the deaths, it’s dubious to say the reduction of lortab “caused all those on the street abusing oxycodone to switch to heroin/fentanyl”. The problem is the low cost of illicit, Chinese Fentanyl is laced into Heroin and even knock-off internet Lortab and the Fentanyl is killing people.

    3. What did you tell the new pain clinics as to the reason you were there. They had to know that you left another doc and came there, which by the way gets you labeled a drug seeker even though you just want what works

    4. Mark,, loved the comment, everyone is different! Take me I’m a full blown pill addict who always has a job but would be broke not only on payday but two weeks prior thanks to yo being able to go on the books… anywho
      I am on 90 mg of dome since 2012 I can tell you my quality of life skyrocketed have a fiance a vehical that is paid off which I completely get is second nature for most!! However in the seven years I have witnessed more than my fair share of waiting in line at the clinic hearing stories of how bad it’s going to be and how you’re going to be on it the rest of your life… I mean it was like many soap operas also here people say that you won’t even be able to think from the pain of yours hallowed aching joints for as many years as you’ve been on it if not more. Trust me I’m down playing the story I mean it’s been seven years you hear a lot of things.. to make a long story even longer I had run into a situation where I missed 17 days of dosing!!! Oh crap here we go 7 years of stories and and scary thoughts pouring through my head!!!OHHH here we go its been long time but I could never forget you misery you where such a big part of my life for so long.. now I’ve read about a hundred comments and I’m still unsure what this sites really about, I’m not here to condone or promote methadone,, truly I’m really here trying to find out ways to come by my treatment a little cheaper I mean 7 years that adds up just cuz for the majority of my life I would spend it within 30 minutes of cashing my pacheck it never got easier to see it go. But after reading Mark comments I felt I needed to say for the third time that everybody is different it wasn’t fun I had a crappy days I don’t need to go to the list of stuff everybody knows that always comes with abruptly stopping such a high dose of anything.. alright I’m going to wrap it up I’m back at the clinic now thank my lucky stars everything’s back to normal I missed it so much, I don’t lie to myself it’s going to more than likely be a daily thing the rest of my life Im fool apart from my run along sentences incorrect punctuation and horrible grammar I mean they did take a toll but I know my happiness comes at a cost probably will take 10 if not more years off my life but that’s years I didn’t have before… man that was a long story just to say don’t read into all the hype and trust me you will make it, Maybe. Have a good night

  42. I just left the office of my new PM doctor. I was with my previous PM doctor for 7yrs. He retired @64, good for him, not me. I’ve been on oxycodone 30mg plus neurontin & topamax. My lowest pain level since a surgeon cut the nerves on wrong side lumbar spine, on meds, is a 4. I’m fine with that as I don’t feel anything will take the pain away. At any rate, the new DOC wants to switch me to methadone, pending a DNA marker test. The DNA test has me aghast. The thought of switching to methadone has me afraid. I saw how my ex responded to a short stint for pain. Then there’s the horror stories in the media. I moved to take care of my grandson. I’m also confused as to why a doctor would switch someone not tolerant or an abuser. This was my first appt! To me, he’s immediately questioning my other Dr. He stopped letting his patients use the CVS around the corner because the pharmacist questioned a prescription. Should I be worried? When you’re on this medicine, you feel like you’ve got a huge sign saying ADDICT. For me, I can live without oxycodone if I thought it was for better pain control. I can’t stand to take any more of them than is prescribed or I get sick. There’s no high effect for me so I’m not taking them for that. Any opinions, suggestions, or advice? Thanks in advance.

    1. Deborah, I really can’t comment on your case specifically without all the information, and if if I had it, I can’t give advice via this forum. But I will say this; if your new doctor is very familiar with methadone dosing, it generally works better than oxycodone for burning / shooting pain because it blocks a chemical called NMDA. If your new doctor is testing you genetic type for cytochrome 2B6, that is a cautious approach to ensure you aren’t at higher risk of accumulating the “S” form of methadone. Perhaps things will get better for you with the new doctor, as it sounds to me like he/she may be on the right track. See 31.Zorn KE, Fudin J. Treatment of Neuropathic Pain: the Role of Unique Opioid Agents. Practical Pain Management. 2011 May; 11 (4): 26-33.

      1. Please help me i am On 50mg metadone and 24mg Dilaudid for Break Though Pain Well I Am going To Be Out For 2 Days Of my Dilaudid because My Pain Was out of Control Bc i was Diagnosed With a new Painful Dieases called GOUT.PAIN Hands feet plus have CRPS RA PSORIATIC ARTHRITIS LUNG DISEASE NEUROPATHY NERVE PAIN ANXIETY AND PANTIC ATTACKS AND CHRONIC FATIGUE CHRONIC NAUSEA CHRONIC PAIN ON OXYGEN Just want to know will that Help plus on 0.5Ativan and Phenergan 25mg thank You

        1. Methadone changed my life for the better. Well, for the best. I know these drugs work different for different individuals. For me, I was on Norco 10mg 4x daily and after being on that for years, it stopped working almost all together. The methadone made my life normal again. I could function so much better since I wasn’t focusing on the pain anymore. To each their own, but for me it worked great.

          1. Thanksthat just happened to me last month. I was looking for how others felt after awhile and if methadone worked better than 4 Norco a day. I get 3norco for in between a ten methadone morning and same at night…. Thank you…. from Judy Zbleski Linder.

    2. Don’t get on methadone! I’ve had 2 back surgeries and was on everything from oxycontin to fentanyl. Methadone is horrible! The stigma of it is awful and I wished I’d never switched. It’s the hardest thing to get off of too. Way worse than any other opiate I’ve been on. You should be worried and switch doctors now before he changes amything bc you wont get it back! Been thru this and the stigma really sucks! Dr’s talk to you like your scumbag drug user,very unfair but it’s how it is. Please read about methadone, it wasn’t supposed to be used forever or to manage pain. Thats just my experience, good luck!

      1. U,don’t know what U R TALKING ABOUT! It doesn’t work for everyone but it works better for a burning stabbing pains WHICH I Gave CUZ I have A disease called INTERSTITIAL CYSTITIS. 60% of People with my disease Commit Suicide CUZ the pain is so…. horrible! Methadone GAVE ME MY LIFE BACK!

        1. I am in the same boat. I have pain in the thoracic area of my back. 40 mg. Of methadone and I have my life back. The last Dr reduced me to 25 mg. Per day and its just awful. I try to save them up so I can take the 40 mg per day but its just about impossible. When I do save them up I just stop taking them and I do not have bad systems to this day. I wish I knew where to go for the fill amount. By the way, 40mg is not a lot and the first Dr that put me on it did EKG’s with a note ” for long term methadone use”. I wish he was still around.

        2. Lori rn I totally agree with you. I also have a horrible very painful disease r.s.d and I hate when people don’t know what they are talking about. First of all they probably don’t even know methadone was made primarily as a pain killer during ww2 bc allies cut off the German opium supply so they had to come up with a synthetic pain med now known as methaone,dolophine,or methadone but a lot of PM dr.s use methadone for pain not bc ne or she thinks of u as a junkie or whatever ever else deziray put. It’s a essential tool in PM dr.s arsenal and if pharmacies give u a look or whisper to one another bc of your script $%&* them

        3. Thanks Lori cuz I was going to say the same thing I have Crohn’s and lupus disease and methadone has saved my life and it also has given me my life back not having to worry about changing the patch on my body every 3 days or taking pills every 3 hours it’s one dose a day and I’m not paying free but I can live with the pain I do have. thanks and good luck to you in the future

      2. This is so true. As wonderful methadone is for pain it is also evil. When i went to my first pain doc i was on oxycontin and it worked fine, but he uses methadone. I had no choice. Now 7yrs later of 20mg a day of methadone he switches everyone to the lowest dose of Embeda 20mg and 9 wks later im still having severe restlessness period from being taken off Methadone. They don’t care. “it will get better”

      3. Been on methadone for 18 years ..went from 40mg a day to 25mg , it was no cake walk.I cut it back from 15mg to 10mg because of constipation problems from Colon cancer.After I got past 15 mg I entered a living HELL now for 26 months with PAWS..Methadone and Suboxone the 2 drugs made by man to help addicts is a worse and harder addiction to withdraw from than the drug people are addicted to.I know people who craved for 3 years straight every day like me and they went cold turkey. I am still taking 10mg and have had PAWS for 2 years ..This stuff is poison. Most will never get off either .it’s harder than opiates.

    3. Get a different doc. Do not switch to methadone if you are not addicted. Methadone has helped me a lot but with methadone you have to go get it EVERYDAY. Only addicts should need that structure…it would be unfair to make a non addict go through that. And I am pretty sure a doctor cannot tell you which pharmacies you may or may not use. I would report this doc if I were you…

      1. If you are a pain patient, you shouldn’t have to go to a methaodne “clinic” daily? Your pain doc or primary doc should be treating your pain, even with methadone. Those daily clinics are for heroine or drug abuser/users, who need something to get off of heroine (usually, although some may be addicted to and buying other opiates off of the street. Any real patient in pain should be at the government “metbaodne clinic.” This is absurd, your primary doc should be competent enough to treat your pain by gauging it through MRI, X-ray, your quality of life, etc. I would call my primary doc if I was you, because he is the one who switched you, right?