WARNING: ONLY EXPERIENCED CLINICIANS SHOULD ATTEMPT TO CONVERT TO OR FROM METHADONE, AND IN ALL CASES, THE CALCULATED DOSE IS ONLY INTENDED TO PROVIDE A POSSIBLE TARGET DOSE AFTER SLOW TITRATION. PATIENTS SHOULD NEVER BE CONVERTED WITHOUT A SLOW TITRATION AND CAREFUL ADJUSTMENT.
METHADONE DOSING and CONVERSION
- Opioid Conversion Calculator
- Methadone EKG Monitoring Recommendations
- Mathematical Model For Methadone Conversion Examined or PPM HTML Version
- Methadone Dose Conversion Unscrambled (related blog post)
- Fudin Factor (methadone conversion equation)
See also, METHADONE Rx & Safety at Pain-topics.org.
Related Articles:
1. Krantz MJ, Lowery CM, Martell BA, Gourevitch MN, Arnsten JH. Effects of Methadone on QT-Interval Dispersion. Pharmacotherapy. 2005;25 (11):1523–1529.
2. Kuehn Bridget M. Methadone Overdose Deaths Rise With Increased Prescribing for Pain. JAMA, August 22/29, 2012—Vol 308;8;749-750.
“In Washington state, … the state’s decision to list methadone as a preferred painkiller to cut costs contributed to increasing numbers of overdoses among patients covered by Medicaid.”
“In Washington state, … the state’s decision to list methadone as a preferred painkiller to cut costs contributed to increasing numbers of overdoses among patients covered by Medicaid.”