Action of buprenorphine.

QuestionsCategory: OpioidsAction of buprenorphine.
Jacqueline asked 4 months ago

Dr. Fudin, you mention in an article buprenorphine works at the spinal level unlike in the brain as traditional opioids. Can you please elaborate on that? Does that have any bearing on it relieving pain better? Are there other pain medications that have similar action?

As always, my deepest gratitude for educating us!

1 Answers
Jeffrey FudinJeffrey Fudin Staff answered 4 months ago

Jacqueline, Please see Gudin J, Fudin J. A narrative pharmacological review of buprenorphine: a unique opioid for the treatment of chronic pain. Pain and Therapy. 2020. It is available at